Article
Biochemistry & Molecular Biology
Noah Neidigh, Alyssa Alexander, Parker van Emmerik, Allison Higgs, Logan Plack, Charles Clem, Daniel Cater, Nadzeya Marozkina, Benjamin Gaston
Summary: A noninvasive device using ultraviolet light was developed to measure S-nitrosothiols in mammalian tissues. The method was sensitive, specific, and reproducible in rats and humans. This approach may have implications for studying human diseases.
Article
Spectroscopy
Artem A. Mikhailov, Theo Woike, Axel Gansmuller, Dominik Schaniel, Gennadiy A. Kostin
Summary: Photoinduced NO-linkage isomers in a labelled trans-[Ru((NO)-N-14/15)(py(4))F](ClO4)(2) complex were investigated in the solid state using IR-spectroscopy and DFT calculations. The experimental data and calculations allowed for a complete assignment of vibrational bands and provided insights into the structural changes leading to the downshift of certain bands. Long-time irradiation may induce irreversible reactions, such as the release of NO or nitrous oxide N2O.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Horticulture
Sitthisak Intarasit, Bualuang Faiyue, Jamnong Uthaibutra, Kobkiat Saengnil
Summary: The research aimed to investigate the impact of chlorine dioxide (ClO2) on the browning of longan pericarp. The findings indicated that ClO2 fumigation reduced the activities of RNS producing enzymes, resulting in lower nitrosative stress levels and reduced pericarp browning.
SCIENTIA HORTICULTURAE
(2022)
Article
Chemistry, Applied
Ri Han, Rachel Andrews, Christopher O'Rourke, Stephanie Hodgen, Andrew Mills
Summary: The study examined the impact of photocatalytically generated surface HNO3 on NOx and VOC removal activity using different photocatalytic films, showing varied performance. The STO paint and P25 films exhibited decreased activity after irradiation, while the IKEA fabric retained its activity due to its fibrous nature. The presence of a HNO3 film had a negative effect on NOx removal activity, but did not significantly affect the oxidation activity of acetaldehyde.
Article
Chemistry, Physical
Hongying Li, Bicheng Zhu, Jian Sun, Haiming Gong, Jiaguo Yu, Liuyang Zhang
Summary: Compared to hydrogen production through pure water photocatalysis, utilizing seawater directly for hydrogen production is more in line with the principles of sustainable development. RuO2 and TiO2 have been widely recognized to exhibit good stability in seawater. This study investigates hydrogen production in simulated seawater using a RuO2-modified TiO2 model system. The results show that the hydrogen production activity of TiO2/RuO2 nanofibers in simulated seawater is comparable to that in pure water.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2024)
Article
Engineering, Environmental
Libin Tan, Qiaomei Yang, Longpeng Peng, Can Xie, Kun Luo, Liyi Zhou
Summary: This study reports a dual-response fluorescent sensor CGT for simultaneous detection of bisulphites and nitrites. The results show that CGT has good detection capability for HSO3- and NO2- in complex aqueous samples and biosystems.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Engineering, Environmental
Michal Baudys, Rachel Andrews, Ri Han, Christopher O'Rourke, Stephanie Hodgen, Josef Krysa, Andrew Mills
Summary: Three commercial exterior photocatalytic paints and one In-house paint were tested using NO ISO method, showing little or no photocatalytic activity without weathering. Different paints require different weathering conditions for activation, with the STO paint showing fast and durable activation through condensation-only weathering. The presence of surface HNO3 affects the NOx removal activity of all paints towards the end of the irradiation period.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Medicinal
Maryam Akhtar, Jiabin Niu, Yujie Zhu, Zhaoyi Luo, Ting Tian, Yuanliang Dong, Yuan Wang, Muhammad Subaan Fareed, Li Lin
Summary: In this study, a combination of design, synthesis, computational study, in-vitro screening, and in-vivo evaluation was used to accelerate the discovery of anti-inflammatory drugs. The newly synthesized compounds exhibited strong dose-dependent inhibitory effects on nitric oxide (NO) release, with no obvious cytotoxicity. Several model compounds (7a, 7b, 7d, 7f, and 7g) showed promising anti-inflammatory activity in the in-vitro assay, with IC50 values ranging from 20.76 mu M to 47.8 mu M. Furthermore, these compounds demonstrated inhibition of ear edema in mice, indicating their potential as anti-inflammatory agents.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Engineering, Environmental
Jithin Gopakumar, Pal Martin Benum, Ingeborg-Helene Svenum, Bjorn Christian Enger, David Waller, Magnus Ronning
Summary: This study summarizes the use of a gamma-Al2O3 supported Ru catalyst for the oxidation of NO to NO2 in industrial nitric acid production. The catalyst exhibited high activity and kinetic parameters under nitric acid plant conditions, and the apparent activation energy and reaction mechanism were investigated.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Analytical
Giacometta Mineo, Kaveh Moulaee, Giovanni Neri, Salvo Mirabella, Elena Bruno
Summary: This article reports the hydrothermal synthesis of WO3 nanorods and their application in NO sensing. The study found that WO3 nanorods have fast response and recovery times, which opens the possibility for the development of fast NO sensors based on WO3.
Article
Biochemistry & Molecular Biology
Sigal Fleisher-Berkovich, Yvonne Ventura, Maya Amoyal, Arik Dahan, Valeria Feinshtein, Leenor Alfahel, Adrian Israelson, Nirit Bernstein, Jonathan Gorelick, Shimon Ben-Shabat
Summary: Cannabigerol has the potential to be a therapeutic agent for the treatment of Multiple Sclerosis, as it can reduce neuroinflammation and neuronal loss. It acts by inhibiting the production of nitric oxide and tumor necrosis factor-alpha.
Article
Biophysics
Hongen Chang, Mingzhu Huo, Qingxiang Zhang, Mengmeng Zhou, Youlin Zhang, Yuxin Si, Di Zhang, Yi Guo, Yuxin Fang
Summary: Researchers have developed an implantable needle-type microsensor that can monitor the release of adenosine in response to acupuncture in real-time. The sensor can measure adenosine levels at a low applied potential, and has a wide linear range and high sensitivity. Animal studies have demonstrated the positive correlation between acupuncture-induced adenosine release and the intensity levels of the stimulus, showing the potential of the sensor for analyzing the physiological effects of acupuncture.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Energy & Fuels
Chirag Mevada, Mausumi Mukhopadhyay
Summary: The study presented an effective strategy for fabricating AASC with ultra-high mass loading of electroactive materials, utilizing electrodeposited ruthenium oxide on carbon cloth as a current collector. By spin-coating tin oxide and titanium dioxide nanoparticles on the current collector, the AASC exhibited promising electrochemical properties with a maximum areal capacitance of 58 mF cm(-2) and capacitance retention rate of 86.5% after 10,000 charge-discharge cycles.
JOURNAL OF ENERGY STORAGE
(2021)
Article
Biochemistry & Molecular Biology
Luna Song, Hehe Bai, Chenyang Liu, Wenjun Gong, Ai Wang, Li Wang, Yi Zhao, Xuan Zhao, Hongfei Wang
Summary: Two light-activated NO donors [RuCl(qn)(Lbpy)(NO)]X were synthesized and characterized using various spectroscopic techniques. One complex showed higher binding constants with human serum albumin and DNA, with HSA acting as a carrier to facilitate NO release from the complexes upon photoirradiation. Confocal imaging successfully demonstrated photo-induced NO release in living cells.
Article
Peripheral Vascular Disease
Fulye Argunhan, Dibesh Thapa, Aisah Aniisah Aubdool, Emanuele Carlini, Kate Arkless, Erica Ruth Hendrikse, Joao de Sousa Valente, Xenia Kodji, Brentton Barrett, Carlo Alberto Ricciardi, Luigi Gnudi, Debbie Lucy Hay, Susan Diana Brain
Summary: CGRP plays a protective role in cardiovascular function by restoring blood pressure and preventing cardiovascular remodeling when nitric oxide production is diminished. Endogenous CGRP acts to protect cardiovascular function, while exogenous CGRP can rescue affected mice.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)