Article
Chemistry, Analytical
Mohammad Reza Jalali Sarvestani, Tayyebeh Madrakian, Abbas Afkhami
Summary: In this study, a highly sensitive electrochemical sensor was developed for the detection of ultra-trace levels of Pb2+. The sensor was modified with an in-situ electroplated bismuth film and a nanocomposite of a recently synthesized melamine based covalent organic framework and Fe3O4 nanoparticles. The combination of Fe3O4@SNW1 and the bismuth film significantly enhanced the sensitivity of the sensor towards Pb2+. The optimized sensor showed a linear response in the concentration range of 0.003-0.3 μmol L-1 with a detection limit of 0.95 nmol L-1. The sensor demonstrated good selectivity towards Pb2+ and was successfully applied for the determination of Pb2+ in different edible specimens.
Article
Electrochemistry
Marzena Adamczyk, Malgorzata Grabarczyk
Summary: A novel solid bismuth microelectrode combined with adsorptive stripping voltammetry was used to develop a simple and fast method for tin determination. The method involved the formation of a tin complex with cupferron in solution and deposition on the solid bismuth microelectrode. Optimal parameters were determined to achieve a linear response and a low detection limit for Sn(II), and interferences from foreign ions and organic matrix were studied.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Article
Chemistry, Analytical
Joanna Wasag, Malgorzata Grabarczyk
Summary: This work introduces a new fast and sensitive method for voltammetric determination of Al(III) as Al(III)-cupferron complexes, which was used for analyzing solutions from exposed aluminum alloy AA2024. Optimized experimental conditions and procedures led to promising results, with a linear calibration graph and good accuracy demonstrated through analysis of synthetic samples.
Article
Chemistry, Analytical
Merzak Doulache, S. Irem Kaya, Ahmet Cetinkaya, Nurgul K. Bakirhan, Mohamed Trari, Sibel A. Ozkan
Summary: In this study, an electrochemical sensing platform was prepared for the determination of regorafenib using multi-walled carbon nanotubes modified glassy carbon electrodes. The platform showed improved response signal and successful detection of regorafenib in various samples, including human serum and pharmaceutical tablet dosage forms.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Ceren Yildiz, Dilek Eskikoy Bayraktepe, Zehra Yazan, Muserref Onal
Summary: This study presents a electrochemical sensor based on pencil graphite electrode and its application in the quantification of heavy metals. The sensor has a high conductive surface area, capable of producing high signals, making it more suitable for electrochemical analysis compared to unmodified electrodes.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Hui Li, Jie Zhao, Shifan Zhao, Guofeng Cui
Summary: A novel three-electrode sensor was developed for simultaneous detection of Pb(II), Cd(II), and Zn(II) by depositing a bismuth film on a screen-printed gold working electrode. The sensor showed a wide linear range, low detection limits, good anti-interference ability, and stability. Such sensors are expected to be useful for portable heavy metal detection applications.
MICROCHEMICAL JOURNAL
(2021)
Article
Electrochemistry
Nelia A. Sanga, Nazeem Jahed, Zandile Leve, Emmanuel I. Iwuoha, Keagan Pokpas
Summary: This study developed a novel method for simultaneous detection of Cd2+, Cu2+, Pb2+, and Zn2+ concentrations using electrochemically reduced graphene oxide (ERGO) sheets in combination with low-cost disposable pencil graphite rods and in situ plated thin mercury films (HgF). The technique showed improved sensitivity and negligible intermetallic interferences, and was successfully applied to trace metal determination in tap water.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Article
Electrochemistry
Eman A. Al-Harbi
Summary: A highly sensitive SW-ASV methodology combined with a BiF/GCE electrode was successfully employed to detect CTZ drug at trace levels in aqueous media at pH 8.0, with a linear range of 5.0 x10(-9) - 1.2x10(-6) mol L-1 and high accuracy in detection.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2021)
Article
Chemistry, Analytical
Debora A. R. Moreira, Dilton M. Pimentel, Mariane O. B. Arrieiro, Sandro L. Barbosa, Rodrigo A. B. da Silva, Wallans T. P. dos Santos
Summary: This study reports the voltammetric behavior and determination of clonidine (CLO) using an unmodified glassy carbon electrode (GCE) for the first time. CLO exhibited only an irreversible oxidation process on the GCE at pH 12 (vs Ag/AgCl). The determination of CLO was optimized in 0.1 mol L-1 phosphate buffer solution at pH 12.0 using differential pulse voltammetry (DPV), providing a good linear range and low limit of detection for quality control of this drug in pharmaceutical samples. The proposed GCE-DPV method demonstrated good accuracy and analytical performance for CLO determination in pharmaceutical samples, offering a faster, simpler, and lower-cost alternative for quality control compared to other methods.
Article
Chemistry, Analytical
Heleni Panagopoulou, Anastasios Economou, Christos Kokkinos
Summary: This paper introduces a 3D-printed microfluidic device for the determination of Pb(II) and Cd(II) using SIA-ASV method. The device enables online preconcentration and static solution detection, achieving low detection limits and good repeatability.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Vrysiida Partheni, Konstantinos Svarnias, Anastasios Economou, Christos Kokkinos, Peter R. Fielden, Sara J. Baldock, Nicholas J. Goddard
Summary: This work presents a sequential injection analysis method for simultaneous determination of Pb(II), Cd(II) and Zn(II) using an injection-moulded electrochemical fluidic chip. The method demonstrates high sensitivity and reliability, with quantification limits of 2.8 μg L-1 for Pb(II), 3.6 μg L-1 for Cd(II) and 4.2 μg L-1 for Zn(II). Additionally, the method was successfully applied to trace metal determination in fish food samples.
Article
Chemistry, Analytical
Zandile D. Leve, Nazeem Jahed, Nelia A. Sanga, Emmanuel I. Iwuoha, Keagan Pokpas
Summary: A simple, highly sensitive, accurate, and low-cost electrochemical sensor was developed for the determination of over-the-counter painkiller, paracetamol (PC). The enhanced sensing capabilities of the developed sensor were fabricated by the single-step modification of disposable pencil graphite electrodes (PGEs) with the simultaneous electrochemical reduction in graphene oxide and antimony (II) salts.
Article
Biochemistry & Molecular Biology
Malgorzata Grabarczyk, Marzena Adamczyk, Edyta Wlazlowska
Summary: This paper presents the first use of an environmentally friendly solid bismuth microelectrode for quantifying V(V) in natural water samples. The proposed procedure replaces the use of highly toxic mercury-based sensors, utilizing electroactive complexes with cupferron for preconcentration of V(V) at the electrode surface. Activation of the solid electrode surface significantly improves analytical parameters. The method is highly selective and accurate.
Article
Chemistry, Analytical
Reyhan Dincer, Sukriye Ulubay Karabiberoglu, Zekerya Dursun
Summary: This study proposes a dependable approach for the selective and sensitive identification of zinc, cadmium and lead in different sample matrices using an over-oxidized poly(xylenol blue) film glassy carbon electrode coated with bismuth (Bi/PXBov.ox/GCE). The best conditions for determining these elements were found to be a 0.1 mol L-1 acetate buffer solution as supporting electrolyte (pH 4.5), -1.5 V accumulation potential, and 180 s accumulation duration. Under these conditions, the detection limits of Zn(II), Cd(II) and Pb(II) were 3.20 μg L-1, 0.21 μg L-1 and 1.98 μg L-1, respectively. Moreover, this novel, cheap and easy-to-prepare Bi/PXBov.ox/GCE was successfully used for the analysis of Zn(II), Cd(II) and Pb(II) in lipstick samples, with consistent results compared to inductively coupled plasma mass spectrometry.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Anton A. Ciucu, Mihaela Buleandra, Tatiana Ciurea, Vlad N. Stoica, Cristian D. Stefanescu, Adela Ciobanu
Summary: A new linear sweep voltammetric method using an electrochemically pre-treated pencil graphite electrode (PGE*) for quantitative determination of lamotrigine (LMT) was presented. The method showed a wide linear range of 2.5 . 10(-5)-1.0 . 10(-3) M with a detection limit of 1.94 . 10(-5) M, and successfully applied for LMT determination in a pharmaceutical formulation.
Article
Chemistry, Physical
Vitoria Pistori Guimaraes, Julio Nandenha, Luiz Otavio Orzari, Orlando Fatibello-Filho, Almir Oliveira Neto, Bruno Campos Janegitz, Fernando Campanha Vicentini, Monica Helena Marcon Teixeira Assumpcao
Summary: This study investigates the use of Pd nanoparticles supported on physical mixtures of Vulcan carbon and TiO2 in different ratios. The presence of TiO2 promotes formate oxidation, and the proportion of 75:25 of carbon and TiO2 shows the highest efficiency.
Article
Chemistry, Multidisciplinary
Mohsin Amin, Badr M. M. Abdullah, Stephen R. R. Wylie, Samuel J. J. Rowley-Neale, Craig E. E. Banks, Kathryn A. A. Whitehead
Summary: This study developed a MWCNT-based enzymatic biosensor for the voltammetric detection of cadaverine. The biosensor exhibited high sensitivity and linear concentration dependence, and it was also effective when tested in artificial saliva.
Article
Green & Sustainable Science & Technology
Phatsawit Wuamprakhon, Robert D. Crapnell, Evelyn Sigley, Nicholas J. Hurst, Rhys J. Williams, Montree Sawangphruk, Edmund M. Keefe, Craig E. Banks
Summary: This study reports the first recycled conductive poly(lactic acid) filament derived from post-industrial waste sources for additive manufacturing. The filament utilizes recycled PLA, carbon black, and polyethylene glycol to produce aqueous AM symmetric supercapacitor platforms with capacitance values 75 times higher than commercially available conductive PLA filaments. By changing the electrode architecture from solid to a mesh with additional inter-layer spacing, the electrode performance can be further enhanced.
ADVANCED SUSTAINABLE SYSTEMS
(2023)
Article
Chemistry, Analytical
Rodrigo Vieira Blasques, Paulo Roberto de Oliveira, Cristiane Kalinke, Lais Canniatti Brazaca, Robert D. D. Crapnell, Juliano Alves Bonacin, Craig E. E. Banks, Bruno Campos Janegitz
Summary: In this study, a flexible disposable printed electrode based on a platinum thin film on bio-based poly (ethylene terephthalate) (Bio-PET) was developed for the monitoring of COVID-19 biomarkers. The electrode, combined with 3D printing technology, allowed for portable and easy analysis with low sample volume. The effectiveness of the electrode was demonstrated through the detection of L-cysteine and the SARS-CoV-2 spike protein, showing its potential as an alternative platform for COVID-19 diagnosis in the future.
Article
Chemistry, Analytical
Lismery P. Souza, Alan R. F. Lima, Thomas A. C. Martins, Fernando Campanha Vicentini, Luiz Humberto Marcolino Jr, Marcio F. Bergamini
Summary: A simple and effective electrochemical sensor using mercury nanodroplets supported on montmorillonite (MMT) was developed for cobalt detection. Physical analyses confirmed the presence of mercury structures in MMT-Hg2+ with nanometric dimensions between 3 and 11 nm. The sensor exhibited a low detection limit, high sensitivity, and wide linear range for cobalt determination.
ANALYTICAL LETTERS
(2023)
Article
Chemistry, Analytical
Bruno C. Janegitz, Robert D. Crapnell, Paulo Roberto de Oliveira, Cristiane Kalinke, Matthew J. Whittingham, Alejandro Garcia-Miranda Ferrari, Craig E. Banks
Summary: The development and increase in crop production have led to the need for greater efficiency and pesticide consumption. The widespread use of pesticides has caused a decrease in pollinating insects and food contamination. Therefore, simple, low-cost, and quick analytical methods are needed to check food quality, such as honey.
ACS MEASUREMENT SCIENCE AU
(2023)
Article
Chemistry, Multidisciplinary
V. Manikandan, G. Ayyannan, Iulian Petrila, Rajaram S. Mane, Kamil Sobczak, J. Chandrasekaran, Robert D. Crapnell, Craig E. Banks
Summary: Ni-doped alumina nanoflakes show efficient and fast response to target gas SO3 at different concentrations, with improved response and shorter response time at higher temperatures. The sensor demonstrates stability and reproducibility over a long period of testing, making it suitable for practical applications. The Ni-dopant enhances oxygen adsorption and active sites, contributing to the excellent sensing properties.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Pengfei Zhu, Zhipeng Jiang, Wei Sun, Yue Yang, Debbie S. Silvester, Hongshuai Hou, Craig E. Banks, Jiugang Hu, Xiaobo Ji
Summary: By establishing an anionic equilibrium mechanism, 65.6% of lithium was successfully extracted from spent LiFePO4 cathodes and the trapped lithium was further extracted by adding phosphoric acid. 90.19% of lithium and 19.88% of phosphorus were recovered as Li3PO4 products.
ENERGY & ENVIRONMENTAL SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Robert D. Crapnell, Iana V. S. Arantes, Matthew J. Whittingham, Evelyn Sigley, Cristiane Kalinke, Bruno C. Janegitz, Juliano A. Bonacin, Thiago R. L. C. Paixao, Craig E. Banks
Summary: This study reports the production of electrically conductive additive manufacturing feedstocks from recycled poly(lactic acid) (rPLA), carbon black (CB), and bio-based plasticizer castor oil. The produced filament was used to print additively manufactured electrodes (AMEs) and compared with commercially available conductive filament. The castor oil/rPLA AMEs showed improved electrochemical performance and were successfully applied to detect bisphenol A (BPA) in water samples.
Review
Chemistry, Analytical
Prashanth S. S. Adarakatti, Robert D. D. Crapnell, Craig E. E. Banks
Summary: This review summarizes the recent advancements in electroanalysis for the sensing of hydroxylamine, a mutagenic and carcinogenic substance. The portable, quick, affordable, simple, sensitive, and selective nature of electrochemical methods make them suitable for monitoring environmental contaminants.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Robert D. Crapnell, Prashanth S. Adarakatti, Craig E. Banks
Summary: Electroanalytical based sensors for ciprofloxacin offer advantages of cost-effectiveness, rapidity, portability, sensitivity, and selectivity, with great potential for future development.
SENSORS & DIAGNOSTICS
(2023)
Article
Engineering, Environmental
Iuri N. Soares, Luis M. C. Ferreira, Monica H. M. T. Assumpcao, Alex Brown, Fernando C. Vicentini, Gabriel L. C. de Souza
Summary: In this study, the photoinduced degradation of tamsulosin was investigated through experiments and computational methods. The experimental results showed that direct photolysis of tamsulosin is efficient, while the catalytic role of solid catalysts is negligible. The computational results indicated that the photoexcited states of tamsulosin may be responsible for the observed photoinduced degradation, which occurs through excited state chemical reactions rather than direct photolysis.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Applied
Luis M. C. Ferreira, Paulo R. Martins, Cristiane G. Silva, Luiz H. Marcolino-Junior, Marcio F. Bergamini, Fernando C. Vicentini
Summary: A lab-made screen-printed electrode based on poly(ethylene terephthalate) substrate modified with a hybrid film containing gold nanoparticles-decorated graphene was developed for the detection of ROX in chicken purge and river water samples. The electrode exhibited enhanced electroactive area and charge transfer due to the presence of nanostructured matrix. The method achieved a limit of detection of 60 nM and 97 nM for ROX in diluted river water and chicken purge samples, respectively.
Article
Biotechnology & Applied Microbiology
Robert D. Crapnell, Prashanth S. Adarakatti, Craig E. Banks
Summary: This minireview presents recent advances in the electroanalytical sensing of oxalate, including an overview of electrode configurations and real sample analysis, as well as comparisons to other analytical methods. The conclusions and future perspectives of this field are also briefly described.
SENSORS AND ACTUATORS REPORTS
(2023)
Review
Chemistry, Analytical
Robert D. Crapnell, Prashanth S. Adarakatti, Craig E. Banks
Summary: This article mainly introduces the use of broad-spectrum systemic fungicide Carbendazim to control fungal diseases in agriculture, horticulture, and forestry, and discusses the methods and advances in detecting Carbendazim using electroanalytical sensors.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
