Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 188, Issue -, Pages 1235-1240Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2013.08.030
Keywords
Rodamine B; Fluorescent probe; Copper ions; HeLa cells; Image
Funding
- 973 Program [2010CB933504]
- National Natural Science Foundation of China [20972088, 90813022]
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An efficient turn-on rodamine-based fluorescent probe for intracellular Cu2+ image in living HeLa cells has been developed. The fluorescent probe exhibits high Cu2+ selectivity and excellent sensitivity (limit of detection is 1.2 x 10(-8) M) in CH3CN/HEPES (1/1, v/v) buffered solution and an immediate fluorescent response toward Cu2+ under physiological conditions. Moreover, the fluorescent probe effectuates the naked-eye detection of Cu2+. (C) 2013 Elsevier B. V. All rights reserved.
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