Article
Chemistry, Analytical
Yan Wu, Rongnan Yi, Honghui Zang, Jing Li, Rong Xu, Fang Zhao, Junli Wang, Cuicui Fu, Jinyang Chen
Summary: In this study, a sensitive, simple, and reliable approach for measuring xanthine in biological liquids was developed using a ratiometric surface-enhanced Raman spectroscopy (SERS) sensing strategy. By measuring the ratio of specific Raman peaks, the xanthine concentration could be quantitatively detected. This novel sensor showed high sensitivity and reliability, providing a new direction for the analysis of other biomolecules.
Article
Chemistry, Physical
Abdelaziz Elgamouz, Abdelnasser Kawde, Salman S. Alharthi, Marwa Laghoub, Dina Miqlid, Chahlaa Nassab, Khalid Bajou, Shashikant P. Patole
Summary: This study describes a green and cost-effective technique for preparing silver nanoparticles stabilized with cinnamon's phytochemicals, which can act as catalysts for hydrogen peroxide and xanthine oxidase, with good catalytic activity and detection performance.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Multidisciplinary
Rui Shi, Qiaoling He, Shiqi Cheng, Bolin Chen, Yilin Wang
Summary: MoS2 nanosheets prepared by the hydrothermal method exhibited peroxidase-like activity and could catalyze the oxidation of TMB. A colorimetric method for measuring glucose concentration was established based on the MoS2 NS-catalyzed reaction, with satisfactory results shown in urine samples.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Gudipati Neeraja Sinha, Palyam Subramanyam, Vanjari Sivaramakrishna, Challapalli Subrahmanyam
Summary: The study presents copper bismuth oxide as a potential electrochemical sensor for the oxidation of uric acid and reduction of hydrogen peroxide, with high sensitivities achieved for both analytes. Structural and morphological studies were conducted to confirm the potential of CuBi2O4 for sensing applications.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Chemistry, Analytical
Chiyu Ma, Liubing Kong, Xianyou Sun, Yanchi Zhang, Xinyi Wang, Xinwei Wei, Hao Wan, Ping Wang
Summary: In this study, an enzyme-free and wide-range colorimetric sensor for uric acid (UA) and hydrogen peroxide (H2O2) detection was developed. By reacting with mercaptosuccinic acid (MSA) modified copper nanoparticles (CuNPs), small Cu particles can be further aggregated into larger particles with a purple-blue color under the action of UA or H2O2. Using a multi-channel handheld automatic photometer (MHAP), the concentration of UA and H2O2 can be determined on-site based on absorbance measurement by photodiodes. This approach has been successfully applied to the detection of UA in human urine, providing possibilities for non-invasive home health monitoring, community medical diagnosis, and on-site disease detection.
Article
Chemistry, Analytical
Khursheed Ahmad, Mahesh A. Shinde, Haekyoung Kim
Summary: The evolution of nanomaterials has played a significant role in tuning material structures and developing applications, with MoS2 and rGO standing out for their excellent properties and wide range of applications. Hybrid structures of MoS2 and rGO, such as MoS2/rGO, have been extensively studied and utilized in electrochemical sensing, energy storage, energy conversion, and photocatalysis applications in recent years.
MICROCHEMICAL JOURNAL
(2021)
Article
Nanoscience & Nanotechnology
Fengna Shi, Jingfang Li, Cheng Chen, Fang Wang, Naipin Chen, Ziqi Xu, Jiajun Wang
Summary: In this paper, a novel non-enzyme electrochemical sensor was developed for the detection of glucose, uric acid (UA), and hydrogen peroxide (H2O2). The sensor exhibited excellent performance in terms of wide linear range, low detection limit, and high selectivity, which can be attributed to the synergistic effect of zinc oxide nanorods and carbon nanotubes. The sensor also demonstrated good reproducibility, stability, and selectivity, and it was successfully applied for the detection of glucose, UA, and H2O2 in human serum.
Article
Chemistry, Analytical
Kangkang Wang, Tingting Yao, Jiayu Xue, Yanqiu Guo, Xiaowei Xu
Summary: Hydrogen peroxide (H2O2), an important reactive oxygen species (ROS), is closely related to various pathological and physiological processes in living organisms. Excessive H2O2 can lead to diseases such as cancer, diabetes, and cardiovascular diseases, necessitating the detection of H2O2 in living cells. This study designed a new fluorescent probe that effectively detects H2O2 with high selectivity and measures cellular ROS levels, providing a potential monitoring tool for various diseases caused by H2O2 excess.
Article
Chemistry, Multidisciplinary
Jinxing Chen, Qian Ma, Zhixuan Yu, Minghua Li, Shaojun Dong
Summary: Researchers have developed a new alloy material, Pt-Au, for synthesizing hydrogen peroxide through the oxidation of formic acid, mimicking the catalytic function of natural enzymes. The alloy exhibits higher catalytic activity and can be used for efficient hydrogen peroxide production, as well as oxidation reactions in an acidic environment.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Engineering, Chemical
Luping Xiao, Lei Ji, Changsheng Yin, Ailiang Chen, Xingyu Chen, Xuheng Liu, Jiangtao Li, Lihua He, Fenglong Sun, Zhongwei Zhao
Summary: A novel method has been developed to dissolve tungstic acid and scheelite hydrochloric acid decomposition residue using hydrogen peroxide, reducing the amount of ammonia wastewater produced during traditional tungsten metallurgy. The research showed that hydrogen peroxide can dissolve tungstic acid and scheelite hydrochloric acid decomposition residue, and the peroxotungstic acid obtained can be easily decomposed into tungstic acid, allowing for clean and efficient leaching of scheelite.
MINERALS ENGINEERING
(2022)
Article
Multidisciplinary Sciences
Ryosuke Watanabe, Shiori Tanaka, Godai Miyaji, Daisuke Yoshino
Summary: Plasma medicine, using atmospheric-pressure plasma, is an innovative therapy attracting attention in the medical field. It can directly or indirectly affect lesions, promoting transdermal absorption for pharmaceutical and cosmetic applications.
SCIENTIFIC REPORTS
(2022)
Article
Environmental Sciences
Shaorui Wang, Qiaowen Li, William A. Stubbings, Lili Li, Junhao Qin, Huashou Li
Summary: The study found that adding Fenton solution can reduce the accumulation of arsenic speciation in rice tissues, while the concentration of iron plaque is enhanced by the presence of Fenton solution and flooded conditions. This suggests the role of Fenton solution in guiding the distribution of arsenic speciation within the soil-rice system and its impact on arsenic accumulation in rice tissues.
Article
Chemistry, Multidisciplinary
Yushuang Liu, Furong Chen, Layue Bao, Wenfeng Hai
Summary: In this study, a label-free and ultrasensitive electrochemical sensor based on graphitic nitride nanosheets was developed for the detection of procalcitonin. The sensor showed a wide dynamic range and a low limit of detection, and demonstrated potential for clinical application in human serum samples.
Article
Green & Sustainable Science & Technology
Peiyao Wen, Jie Chu, Junjun Zhu, Yong Xu, Junhua Zhang
Summary: In this study, a novel hydrogen peroxide-ethyl acetate (HPEA) pretreatment method was developed for the selective removal of poplar lignin at room temperature, while retaining a high percentage of the original carbohydrates. Compared to the traditional hydrogen peroxide-acetic acid (HPAA) pretreatment, HPEA pretreatment exhibited higher safety and stronger delignification capacity.
Article
Chemistry, Analytical
Fanny Girard-Sahun, Pauline Lefrancois, Vasilica Badets, Stephane Arbault, Franck Clement
Summary: This study aims to detect the in situ production of reactive oxygen and nitrogen species (RONS), specifically superoxide anion (O-2(center dot-)), in aqueous buffer solutions exposed to cold atmospheric plasmas (CAPs). The production and accumulation of RONS in the liquids were found to depend on the plasma composition, with N-2-based shieldings providing the highest concentrations of superoxide. The study provides valuable insights into the interactions between CAPs and physiological solutions for biomedical applications.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)