Article
Chemistry, Inorganic & Nuclear
Kamilla M. Alves, Joao Honorato, Luciano M. Liao, Vivianne S. Velozo-Sa, Adriana P. M. Guedes, Jocely de L. Dutra, Alejando P. Ayalla, Javier Ellena, Alzir A. Batista, Pablo J. Goncalves
Summary: This study synthesized, characterized, and tested the cytotoxicity of four new palladium/pyridylporphyrin complexes. The complexes showed selective indexes close to 1.2 against breast cancer cells, and interacted moderately with CT-DNA through hydrogen bonding, π-π stacking, and electrostatic interactions.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Multidisciplinary
Timofey P. Martyanov, Sergey A. Tovstun, Sergey G. Vasil'ev, Elena G. Martyanova, Maxim G. Spirin, Alexey Kozlov, Lyubov S. Klimenko, Sergey B. Brichkin, Vladimir F. Razumov
Summary: In this study, the interaction between InP/ZnS core/shell colloidal quantum dots and mesotetra(3-pyridyl)porphyrin was investigated using fluorescence and NMR spectroscopy. The formation of QD-TPyP associates led to an increase in dye fluorescence intensity and quenching of nanocrystal photoluminescence, primarily due to Forster resonance energy transfer. It was also found that the adsorption kinetics of the dye was not dependent on its concentration, suggesting a limitation in the rate of ligand detachment from the QD surface. NMR data revealed the presence of two different types of QD-TPyP associates, with the former type being more abundant.
JOURNAL OF NANOPARTICLE RESEARCH
(2022)
Article
Chemistry, Physical
J. M. S. Lopes, A. E. H. Machado, A. A. Batista, P. T. Araujo, N. M. Barbosa Neto
Summary: This study presents a new pathway for generating hexaprotonated porphyrins through excited-state absorption, and reveals the formation of a new species during this process. The results show that the photo-protonation mechanism is driven by oxi-reduction reactions catalyzed by the porphyrin itself. Spectroscopic analysis further demonstrates that the emission lifetimes of the pristine and hexaprotonated porphyrins are quenched by chloride ions.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Nelli H. Karapetyan, Gayane V. Ananyan, Yeva B. Dalyan
Summary: The complex formation between ZnTOEPyP4 and cancer DNA was studied compared to healthy DNA, showing that the binding constant and exclusion parameter are pH-dependent, with a higher value observed for cancer DNA.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2021)
Article
Chemistry, Physical
M. A. Gradova, O. V. Gradov, A. V. Bychkova, M. V. Motyakin, I. S. Ionova, A. V. Lobanov
Summary: The interactions between meso-tetra(4-hydroxyphenyl)porphyrin (THPP) and anionic sodium n-dodecyl sulfate (SDS) were studied at different concentrations, revealing the formation of J-type aggregates and changes in fluorescence and light scattering signals. Binding of THPP to SDS micelles and aggregate formation were observed using DLS and EPR spectroscopy. Microscopic observation showed rod-like morphology of microparticles crystallized from dried suspensions of THPP J-aggregates.
Article
Chemistry, Physical
Guo-Lei Zhang, Tian-Yi Yang, Jijie Zhang, Ying-Hui Zhang
Summary: Three types of free base meso-carboxyphenylporphyrins were compared for their photocatalytic activity in water splitting. The presence of -COOH groups was found to significantly enhance the H-2 evolution rate. The study elucidated the mechanism of H-2 evolution and proposed a new approach to design high-performing organic photocatalysts.
Article
Materials Science, Multidisciplinary
M. M. Makhlouf, M. M. Shehata
Summary: This study investigated the effect of introducing metal ion (Zn2+) into the center cavity of macrocyclic meso-tetra(4-pyridyl)porphine, H2TPyP, on its spectroscopic features, showing perturbations in the absorption spectroscopy of H2TPyP due to Zn complexation. The values of optical band gaps increased and dispersion parameters exhibited an increase in their values due to the insertion of Zn atom into H2TPyP. Nonlinear optical parameters such as third-order susceptibility, nonlinear refractive index, and nonlinear absorption coefficient showed a decrease in their values for ZnTPyP films compared to H2TPyP films.
Article
Physics, Multidisciplinary
J. M. S. Lopes, S. N. Costa, E. Silveira-Alves Jr, A. A. Batista, L. R. Dinelli, P. J. Goncalves, P. T. Araujo, N. M. Barbosa Neto
Summary: In this study, we investigated the effects of [RuCl2(PPh3)(2)(CO)(DMF)] and [RuCl2(dppb)(CO)(DMF)] ruthenium complexes on the spectroscopic properties and singlet oxygen generation efficiency of zinc tetra(4-pyridyl) porphyrin (ZnTPyP). Our results showed that these metallic compounds could significantly impact the electronic and vibronic B- and Q-bands, excited-state deactivation processes, and singlet oxygen generation quantum yield of the porphyrin, with their influence being influenced by the ligands present in the ruthenium complexes.
BRAZILIAN JOURNAL OF PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
E. A. Efimova, N. L. Pechnikova, A. V. Lyubimtsev, V. V. Aleksandriiskii, T. A. Ageeva
Summary: New 5,10,15,20-tetra(4-pyridyl)porphyrin- and C-6-C-9 alkyl bromide-based ionic liquids were synthesized with yields of 23-49%. These compounds will serve as key building blocks for creating functional hybrid materials with a defined hydrophilic-hydrophobic balance, allowing for expanded applications of their useful properties. The biological activity of the synthesized porphyrinic ionic liquids was predicted. The cationic porphyrins obtained hold potential interest in medicine, specifically in the development of drugs for ischemic heart disease and cerebral palsy treatment. The purity and structure of the synthesized compounds were confirmed using electronic absorption and H-1 NMR spectroscopy, as well as mass spectrometry methods.
RUSSIAN JOURNAL OF GENERAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Yuriy Zatsikha, Briana R. Schrage, Tanner S. Blesener, Laurel A. Harrison, Christopher J. Ziegler, Victor N. Nemykin
Summary: In this study, a sterically strained 32 pi-electron antiaromatic bis-BODIPY macrocycle was prepared and characterized. The fluorescence in this macrocycle was quenched, unlike regular BODIPYs. The NMR spectra of the macrocycle showed broad signals due to the vibronic freedom of the p-divinylbenzene fragments. EPR spectra in solution and in solid state confirmed the closed-shell quinoidal structure of the macrocycle, ruling out its possible diradicaloid nature.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Syeda Aqsa Batool Bukhari, Habib Nasir, Effat Sitara, Tehmina Akhtar, Muhammed Ramazan Oduncu, Sadia Iram, Lujun Pan
Summary: In this study, a nanocomposite composed of carbon nanocoils and copper tetra(p-methoxyphenyl)porphyrin was reported for the efficient electrochemical detection of dopamine. The sensor exhibited good detection performance and stability in clinical samples.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Editorial Material
Chemistry, Multidisciplinary
Mariya V. Tesakova, Sergey A. Syrbu, Vladimir I. Parfenyuk
Summary: The polyporphyrin films were synthesized through the electrooxidative polymerization of 5,10,15,20-tetra(4-pyridyl)porphyrin, which was obtained by condensation of pyrrole with pyridine-4-carboxaldehyde. The resulting polyporphyrin films form an electroconductive coating with semiconductor properties, exhibiting a band gap of 1.76 eV.
MENDELEEV COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Pan Li, Xiaorui Jia, Jinping Zhang, Jieqiong Li, Jinqiang Zhang, Lijing Wang, Junmei Wang, Qingfeng Zhou, Wei Wei, Xiaoli Zhao, Shuaijun Wang, Hongqi Sun
Summary: The construction of hybrid catalysts composed of inorganic semiconductors and molecular catalysts shows great potential for achieving high photocatalytic carbon dioxide (CO2) conversion efficiency. This study investigates the roles of different noble metal nanoparticles in charge separation and interfacial electron transfer, and reveals the mechanisms behind the improved photocatalytic performance of the composite material.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Eric M. Kohn, David J. Shirley, Nicole M. Hinds, H. Christopher Fry, Gregory A. Caputo
Summary: Electronics made from biological materials have unique properties that current inorganic technologies cannot achieve. Researchers have developed a series of cationic peptides that can self-assemble with anionic porphyrins into supramolecular light-harvesting wires known as J-aggregates. The J-aggregates can readily interconvert with soluble monomers upon cycling the pH, which has practical and conceptual relevance to the development of new bioelectronic materials.
Article
Chemistry, Multidisciplinary
Su-Hong Peng, Li-Li Wang, Sha-Sha Cai, Hui-Qing Xiao, Xin-Tong Zhao, Hui Wang, Hai-Yang Liu
Summary: UV, FL and IR spectra of different N-confused porphyrin isomers were investigated, showing significant red shifts in UV-vis absorption and fluorescence spectra from o-isomer to p-isomer. The fluorescence lifetime, quantum yield and absorption frequency were influenced by the position of the substituents.
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
(2022)
Article
Chemistry, Analytical
P. Arul, Sheng-Tung Huang, N. S. K. Gowthaman, G. Mani, Nithiya Jeromiyas, Sekar Shankar, S. Abraham John
Summary: In this study, controlled growth of Ni-MOF on amino acid-functionalized graphene nanoplatelets was achieved by a solvothermal approach. The resulting nanocomposite showed a stable response and wide linear range for the oxidation of bisphenol A. The presence of hydroxyl and epoxy functional groups restricted the uncontrolled growth of Ni-MOF, leading to improved electrochemical properties.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Sim Siew Ming, N. S. K. Gowthaman, H. N. Lim, P. Arul, E. Narayanamoorthi, I. Ibrahim, H. Jaafar, S. Abraham John
Summary: In this study, an electrochemical sensor based on Al-MOF (CAU-1-MOF) fabricated glassy carbon electrode (GCE) was utilized for the detection of hydroquinone (HQ), an environmental pollutant. The synthesized CAU-1-MOF showed promising results in HQ detection, demonstrating good sensitivity and anti-interference properties. The proposed sensor also exhibited excellent recovery rates in the determination of HQ in water samples, indicating its practicality and reliability in real-life applications.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Jincymol Kappen, Sinduja Bharathi, S. Abraham John
Summary: The galvanic reaction between graphene quantum dot (GQD)-stabilized silver nanoparticles (AgNP)-modified glassy carbon (GC) surface and Hg(II) leads to the complete dissolution of AgNPs within 15 minutes and the subsequent growth of Hg(0) as a flower on the GQD surface. This unique anti-amalgamation reaction is caused by direct deposition of Hg(0) by available oxygen functional groups and strong adsorption on the GQD graphene surface, followed by subsequent growth of Hg(0) as a flower due to the galvanic reaction between AgNPs and Hg(II).
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Analytical
C. Loganathan, N. S. K. Gowthaman, S. Abraham John
Summary: This study presents a detection method for the organophosphate pesticide quinalphos using ATA-AuNPs, which showed excellent anti-interference ability and high sensitivity. The developed colorimetric and spectrophotometric methods demonstrated good linearity in detection and practicality in determining quinalphos levels in field water and fruit samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
C. Loganathan, K. Muthukrishnan, S. Abraham John
Summary: A simple colorimetric method using graphene oxide-silver nanoparticles (GO-AgNPs) composite solution was developed for the determination of Saccharin (SAC) concentration in food stuffs and soft drinks. Emission intensity increases linearly with SAC concentration and the method was able to selectively determine SAC in the presence of interferents. Real sample analysis of SAC in candies and soft drinks was carried out successfully utilizing this method.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Biotechnology & Applied Microbiology
Manikka Kubendran Aravind, Perumal Varalakshmi, Swamidoss Abraham John, Balasubramaniem Ashokkumar
Summary: The study focused on the first investigation into the C12O gene from Paracoccus sp. MKU1, successfully cloned and expressed in E. coli for ccMA production. The recombinant C12O enzyme showed high affinity to catechol and a unique structure. The whole-cell catalyzed bioconversion of catechol to ccMA by expressing C12O from MKU1 in E. coli demonstrated high efficiency and purity without generating by-products.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Physical
Jincymol Kappen, Manikka Kubendran Aravind, Perumal Varalakshmi, Balasubramaniem Ashokkumar, S. Abraham John
Summary: A sustainable strategy using graphene quantum dots coated carbon cloth is introduced for the remediation of Hg(II) as Hg(0) and its use as a sensor for nitrobenzene. The method shows efficient removal of Hg(II) and sensitive sensing performance.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Electrochemistry
E. Narayanamoorthi, P. Arul, N. S. K. Gowthaman, S. Abraham John
Summary: Morphology controlled synthesis of Cu-MOFs was achieved by using ligands with different aliphatic chain lengths and metal ions with different counterions. The AZA-Cu-MOF showed better electrocatalytic activity for glucose oxidation and can be used for glucose quantification in real samples.
ELECTROCHIMICA ACTA
(2022)
Article
Chemistry, Multidisciplinary
Jincymol Kappen, Sinduja Bharathi, S. Abraham John
Summary: We conducted a comprehensive study on the interaction between transition and heavy metal ions and graphene quantum dots-capped silver nanoparticles (AgGQDs), using various spectroscopic and microscopic techniques. The results showed that metal ions can interact with AgGQDs through selective coordination, adsorption, and direct interaction with silver nanoparticles. The special interaction between heavy metal ions and the graphene surface determines the mechanistic pathway of the reaction.
Article
Chemistry, Multidisciplinary
Ameer Farithkhan, S. Abraham John
Summary: This study successfully grew three-dimensional coral-like NiFe-based layered double hydroxide (NF-LDH) microstructures on nitrogen-doped carbonized wood (NCW) and demonstrated their voltammetric response for urea. The direct anchoring of catalytically active structures on conductive scaffolds eliminated electron transfer resistance and exhibited excellent sensing performance.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Electrochemistry
Ajay Ajith, S. Abraham John
Summary: Electrochemical sensing of uric acid using nitrogen-rich carbon nanomaterials showed promising results, with electrodeposited graphitic carbon nitride exhibiting the highest oxidation current for UA. The practical application in human blood serum samples yielded accurate results.
ELECTROCHIMICA ACTA
(2022)
Article
Environmental Sciences
Kottaikalai Ganesan, Chelvam Hayagreevan, Ramkumar Rahul, Arockiam John Jeevagan, Thambidurai Adinaveen, Durvas Seshian Bhuvaneshwari, Palanisamy Muthukumar, Murugan Amalraj
Summary: In this study, silica and phosphorylated silica were used as catalysts for the hydrolysis of sodium borohydride to produce hydrogen. The phosphorylated silica exhibited higher catalytic activity, possibly due to its acidic functionalities that enhanced the hydrogen production rate. The activation energy and thermodynamic parameters were also calculated, confirming the high activity of phosphorylated silica and the Langmuir-Hinshelwood type reaction mechanism.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Ajay Ajith, S. Abraham John
Summary: This study prepared graphitic carbon nitride nanosheets (GNNS) through different methods and compared their electrochemical performance, showing that GNNS prepared by water exfoliation method have lower impedance and higher electroactive surface area, exhibiting higher catalytic activity towards the reduction of nitrobenzene.
NEW JOURNAL OF CHEMISTRY
(2022)
Proceedings Paper
Materials Science, Multidisciplinary
M. Kavitha, S. Jeyaraj, P. Muthukumar, A. John Jeevagan
Summary: The study reported the synthesis of silver nanoparticles (AgNPs) using Biophytum Sensitivum (B. Sensitivum) leaf extract. The synthesized AgNPs were confirmed to be spherical with an average diameter of 8 nm. The electrocatalytic activity of B. Sensitivum capped AgNPs on glassy carbon electrode (GCE) was found to be enhanced compared to bare GCE, showing potential for application in dioxygen reduction.
MATERIALS TODAY-PROCEEDINGS
(2021)
Article
Chemistry, Multidisciplinary
P. Arul, N. S. K. Gowthaman, S. Abraham John, Sheng-Tung Huang
Summary: A novel carbide material for urea sensor was synthesized in this study, which exhibited a wide linear range and low detection limit. It also showed good performance in urea determination in human biological fluids and milk samples.
MATERIALS CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
