Intravenous multipotent adult progenitor cell treatment decreases inflammation leading to functional recovery following spinal cord injury

The Glia-Derived Alarmin IL-33 Orchestrates the Immune Response and Promotes Recovery following CNS Injury

(2015) Sachin P. Gadani et al.   NEURON

Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

(2015) J. Ruschel et al.   SCIENCE

The paradox of chronic neuroinflammation, systemic immune suppression, autoimmunity after traumatic chronic spinal cord injury

(2014) Jan M. Schwab et al.   EXPERIMENTAL NEUROLOGY

Lymphocytes and autoimmunity after spinal cord injury

(2014) T. Bucky Jones   EXPERIMENTAL NEUROLOGY

High-resolution intravital imaging reveals that blood-derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury

(2014) Teresa A. Evans et al.   EXPERIMENTAL NEUROLOGY

CNS Repair Requires Both Effector and Regulatory T Cells with Distinct Temporal and Spatial Profiles

(2014) C. Raposo et al.   JOURNAL OF NEUROSCIENCE

Modulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injury

(2014) Bradley T. Lang et al.   NATURE

TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord

(2014) Antje Kroner et al.   NEURON

Human Mesenchymal Precursor Cells (Stro-1+) from Spinal Cord Injury Patients Improve Functional Recovery and Tissue Sparing in an Acute Spinal Cord Injury Rat Model

(2013) Stuart I. Hodgetts et al.   CELL TRANSPLANTATION

Mobilisation of the splenic monocyte reservoir and peripheral CX3CR1 deficiency adversely affects recovery from spinal cord injury

(2013) Linda V. Blomster et al.   EXPERIMENTAL NEUROLOGY

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

A Double-Blind Placebo-Controlled Clinical Evaluation of Multistem for the Treatment of Ischemic Stroke

(2013) David C. Hess et al.   International Journal of Stroke

Autonomic Dysreflexia Causes Chronic Immune Suppression after Spinal Cord Injury

(2013) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Nerve Regeneration Restores Supraspinal Control of Bladder Function after Complete Spinal Cord Injury

(2013) Y.-S. Lee et al.   JOURNAL OF NEUROSCIENCE

Intravenous Multipotent Adult Progenitor Cell Therapy Attenuates Activated Microglial/Macrophage Response and Improves Spatial Learning After Traumatic Brain Injury

(2013) Supinder S. Bedi et al.   Stem Cells Translational Medicine

Mechanisms of mesenchymal stromal cell immunomodulation

(2012) Karen English   IMMUNOLOGY AND CELL BIOLOGY

Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population

(2012) Peter A Walker et al.   Journal of Neuroinflammation

Concepts and Methods for the Study of Axonal Regeneration in the CNS

(2012) Mark H. Tuszynski et al.   NEURON

Therapeutic Effects of hMAPC and hMSC Transplantation after Stroke in Mice

(2012) Silvia Mora-Lee et al.   PLoS One

Application of MultiStem® Allogeneic Cells for Immunomodulatory Therapy: Clinical Progress and Pre-Clinical Challenges in Prophylaxis for Graft Versus Host Disease

(2012) Bart Vaes et al.   Frontiers in Immunology

Multipotent Adult Progenitor Cells Prevent Macrophage-Mediated Axonal Dieback and Promote Regrowth after Spinal Cord Injury

(2011) S. A. Busch et al.   JOURNAL OF NEUROSCIENCE

Functional regeneration of respiratory pathways after spinal cord injury

(2011) Warren J. Alilain et al.   NATURE

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Differentiation Potential of Human Postnatal Mesenchymal Stem Cells, Mesoangioblasts, and Multipotent Adult Progenitor Cells Reflected in Their Transcriptome and Partially Influenced by the Culture Conditions

(2011) Valerie D. Roobrouck et al.   STEM CELLS

Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: Preserving the blood brain barrier via an interaction with splenocytes

(2010) Peter A. Walker et al.   EXPERIMENTAL NEUROLOGY

A Systematic Review of Non-Invasive Pharmacologic Neuroprotective Treatments for Acute Spinal Cord Injury

(2010) Brian K. Kwon et al.   JOURNAL OF NEUROTRAUMA

3D Cryo-Imaging: A Very High-Resolution View of the Whole Mouse

(2009) Debashish Roy et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis

(2009) Lillian A Buhler et al.   BMC NEUROSCIENCE

Regulatory T cells: how do they suppress immune responses?

(2009) S. Sakaguchi et al.   INTERNATIONAL IMMUNOLOGY

Stress hormones collaborate to induce lymphocyte apoptosis after high level spinal cord injury

(2009) Kurt M. Lucin et al.   JOURNAL OF NEUROCHEMISTRY

Overcoming Macrophage-Mediated Axonal Dieback Following CNS Injury

(2009) S. A. Busch et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Acute and Chronic Deficits in the Urinary Bladder after Spinal Contusion Injury in the Adult Rat

(2009) Juan J. Herrera et al.   JOURNAL OF NEUROTRAUMA

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

(2009) Arthur Liesz et al.   NATURE MEDICINE

Clinical scale expanded adult pluripotent stem cells prevent graft-versus-host disease

(2008) Magdalena Kovacsovics-Bankowski et al.   CELLULAR IMMUNOLOGY

Another Barrier to Regeneration in the CNS: Activated Macrophages Induce Extensive Retraction of Dystrophic Axons through Direct Physical Interactions

(2008) K. P. Horn et al.   JOURNAL OF NEUROSCIENCE

Neural and anatomical abnormalities of the gastrointestinal system resulting from contusion spinal cord injury

(2008) S. Kabatas et al.   NEUROSCIENCE