Journal
SENSOR LETTERS
Volume 6, Issue 6, Pages 873-877Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/sl.2008.521
Keywords
Biosensor; Antibody; Capacitive; Cardiovascular; C-Reactive Protein
Funding
- Scientific and Technological Research Council of Turkey (TUBITAK) [107E014]
- RF Transmitter-Based Transducer for Biosensor Applications
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This paper presents a biosensor implementation for the detection of protein molecules using specific antibodies. Affinity sensors allow the detection and quantification of target molecules in complex mixtures by affinity-based interactions. Immobilized antibody molecules are the probes that bind to specific protein molecules (targets) in biological fluids. In this study, inter-digitated electrodes in the form of capacitance on glass slide were designed, fabricated and used to measure the changes in the dielectric properties of the inter-digitated capacitances. Our results in this study present that with a careful design of micro-interdigitated capacitors, a wider dynamic range and higher sensitivity can be achieved for the detection and quantification of C-Reactive Protein.
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