Article
Agronomy
Ju-Young Jung, Cheol Woo Min, So Wun Kim, Ravi Gupta, Woojong Jang, Kyong-Hwan Bang, Yu-Jin Kim, Ick-Hyun Jo, Sun Tae Kim
Summary: Ginseng, which is often exposed to environmental stresses such as heat, salt, and drought, has been found to have potential salt-responsive proteins through fluid proteomic analysis. These proteins are associated with photosynthesis, protein synthesis, cell binding, and various metabolisms.
Review
Pharmacology & Pharmacy
Jing Li, Qingxia Huang, Jinjin Chen, Hongyu Qi, Jiaqi Liu, Zhaoqiang Chen, Daqing Zhao, Zeyu Wang, Xiangyan Li
Summary: This review summarizes the effects and mechanisms of Panax ginseng in Alzheimer's disease, as well as its potential use in the prevention and treatment of AD.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Immunology
Dandan Wang, Shuai Shao, Yanqiu Zhang, Daqing Zhao, Mingxing Wang
Summary: The study isolated and studied a polysaccharide from Panax ginseng, finding that it exhibits significant intestinal anti-inflammatory activity by modulating gut microbiota structure and restoring autophagic function to suppress inflammation.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Plant Sciences
Md. Jahirul Islam, Byeong Ryeol Ryu, Md. Obyedul Kalam Azad, Md. Hafizur Rahman, Md. Soyel Rana, Jung-Dae Lim, Young-Seok Lim
Summary: The study demonstrated that exogenously applied putrescine can enhance salt tolerance in Panax ginseng by promoting the accumulation of certain substances and increasing antioxidant enzyme activity. Additionally, the effects of putrescine on ginsenoside levels in ginseng vary depending on the type of ginsenosides and plant parts. These findings provide valuable insights for utilizing putrescine to modulate salt tolerance and ginsenoside content in ginseng sprouts.
Article
Agronomy
Jung-Woo Lee, Jang-Uk Kim, Kyong-Hwan Bang, Dong-Hwi Kim, Ick-Hyun Jo, Young-Doo Park
Summary: This study investigated the regeneration of Panax ginseng through somatic embryogenesis and evaluated the genetic stability of the regenerated plantlets. The results showed that MS medium supplemented with 5% sucrose was optimal for somatic embryo induction, while 1/2 MS medium containing low concentrations of sucrose ranging from 1 to 2% was optimal for maturation. Germination and plant regeneration were optimal in germination medium supplemented with 2% sucrose. Molecular marker analysis indicated that the regenerated plants had comparable genetic fidelity with the control. This study provides valuable insights into the optimization of genetically stable micropropagation of P. ginseng.
Article
Biotechnology & Applied Microbiology
Hongjie Li, Jing Chen, Qi Zhao, Yilai Han, Li Li, Chunyu Sun, Kangyu Wang, Yanfang Wang, Mingzhu Zhao, Ping Chen, Jun Lei, Yi Wang, Meiping Zhang
Summary: A total of 91 bZIP genes were identified in ginseng, grouped into ten clusters and found to express differently across tissues and under drought stress. The study suggests that PgbZIP genes in ginseng play crucial roles in response to drought stress.
Review
Food Science & Technology
Guanyu Lu, Zhuoting Liu, Xu Wang, Chunling Wang
Summary: Panax ginseng has been used as both food and medicine in China for years, and is effective in treating fatigue by enhancing energy metabolism, antioxidant, and anti-inflammatory activity.
Article
Chemistry, Multidisciplinary
Sung Jin Kim, Myoung-Sook Shin, Minyeong Kim, Seung-Hoon Baek, Ki Sung Kang
Summary: The study found that the polysaccharide fraction SGP from ginseng can activate macrophages through the MAPK and NF-kappa B signaling pathways, increasing the production of nitric oxide and cytokines. This may help in maintaining homeostasis during viral and bacterial infections.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Multidisciplinary
Kiyoon Kim, Hyun Jun Kim, Dae Hui Jeong, Jeong Hoon Huh, Kwon Seok Jeon, Yurry Um
Summary: Soil properties play a crucial role in determining vegetation growth, influencing the dominant bacterial community profiles and soil chemical properties. The study focuses on deciphering bacterial community profiles in correlation with soil properties to identify optimal growing conditions for medicinal plants like Wild-simulated ginseng.
APPLIED SCIENCES-BASEL
(2021)
Review
Plant Sciences
Van-Long Truong, Woo-Sik Jeong
Summary: This review provides an overview of red ginseng oil (RGO), focusing on its extraction technologies, chemical composition, health benefits, and safety. The molecular mechanisms underlying the bioactivity of RGO are discussed, along with its potential applications in nutraceuticals, functional foods, and functional cosmetics. Further studies should aim to deepen our understanding of the underlying molecular mechanisms, explore the composition-functionality relationship, and verify the bioactivities of RGO in clinical models.
JOURNAL OF GINSENG RESEARCH
(2022)
Article
Agricultural Engineering
Huixia Lei, Haifeng Zhang, Zhenghai Zhang, Hai Sun, Meijia Li, Cai Shao, Hao Liang, Huping Wu, Yayu Zhang
Summary: Drought stress hinders the increase in ginseng root biomass but promotes ginsenoside accumulation. Physiological analysis showed increased levels of MDA, osmoregulatory substances, and ABA, as well as enhanced activities of SOD, POD, and CAT in ginseng roots under drought stress. Transcriptional analysis revealed DEGs enriched in the plant hormone signal transduction pathway, with twelve DEGs from the ABA signaling pathway identified as key mediators of the drought stress response. Additionally, key enzyme genes involved in ginsenoside synthesis were identified, indicating their role in the response to drought stress in ginseng.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Plant Sciences
Jingli Yang, Jinnan Song, Jayabalan Shilpha, Byoung Ryong Jeong
Summary: Nowadays, ginseng is not only valued for its roots, but also for its leaves and flowers in the supplement and traditional medicine industries. The study found that a combination of top and side lighting directions was the most effective in promoting the growth and development of ginseng.
Article
Plant Sciences
Yue Huo, Jong Pyo Kang, Jong Chan Ahn, Yeon Ju Kim, Chun Hong Piao, Dong Uk Yang, Deok Chun Yang
Summary: The study demonstrated that the siderophore-producing Mesorhizobium panacihumi DCY119(T) has the potential to reduce oxidative stress, enhance heavy metal resistance, and be used for bioremediation of heavy metal contamination.
JOURNAL OF GINSENG RESEARCH
(2021)
Article
Oncology
Hui Jia, Bin Zhao, Fangfang Zhang, Ramesh Kumar Santhanam, Xinying Wang, Jincai Lu
Summary: Polysaccharides extracted from mountain cultivated ginseng showed significant cytotoxic effects against HepG2 cells, particularly with the fraction MTPS-1. Among the seven acidic polysaccharides isolated, MCGP-3 polysaccharide was found to possess a significant cytotoxic effect with low IC50 value against HepG2 cells.
FRONTIERS IN ONCOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Xiaoxue Fang, Manqi Wang, Xinteng Zhou, Huan Wang, Huaying Wang, Hongxing Xiao
Summary: This study investigated the effects of growth years on gene expression in cultivated ginseng and wild ginseng through transcriptome sequencing. The results showed that the growth years significantly affected gene expression in cultivated ginseng, especially in the MAPK signaling pathway and terpenoid backbone biosynthesis pathway. Moreover, the growth years had significant effects on genes related to ginsenoside synthesis in cultivated ginseng but had little influence on wild ginseng.
