4.1 Article

Hirschsprung-associated enterocolitis: prevention and therapy

Journal

SEMINARS IN PEDIATRIC SURGERY
Volume 21, Issue 4, Pages 328-335

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1053/j.sempedsurg.2012.07.007

Keywords

Hirschsprung disease; Enterocolitis; Trisomy 21; Aganglionosis; Rectal stricture

Funding

  1. NIH [1K08DK090281-01]

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Hirschsprung-associated enterocolitis remains the greatest cause of morbidity and mortality in children with Hirschsprung disease. This chapter details the various approaches used to treat and prevent this disease process. This includes prevention of complications, such as stricture formation, prophylaxis with rectal washouts, and identification of high-risk individuals. The chapter also details approaches to diagnose Hirschsprung-associated enterocolitis as well as to exclude other etiologies. (C) 2012 Elsevier Inc. All rights reserved.

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