The pathogenic potential of autoreactive antibodies in rheumatoid arthritis

The concentration of anticitrullinated protein antibodies in serum and synovial fluid in relation to total immunoglobulin concentrations

(2013) Annemiek Willemze et al.   ANNALS OF THE RHEUMATIC DISEASES

MRI of hand and foot joints of patients with anticitrullinated peptide antibody positive arthralgia without clinical arthritis

(2013) Annemarie Krabben et al.   ANNALS OF THE RHEUMATIC DISEASES

Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis

(2013) Aleeza J. Roth et al.   JOURNAL OF CLINICAL INVESTIGATION

Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

(2013) Khaled Amara et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Prevalence of Anti-Peptidylarginine Deiminase Type 4 Antibodies in Rheumatoid Arthritis and Unaffected First-degree Relatives in Indigenous North American Populations

(2013) E. D. Ferucci et al.   JOURNAL OF RHEUMATOLOGY

Erosive Rheumatoid Arthritis Is Associated with Antibodies That Activate PAD4 by Increasing Calcium Sensitivity

(2013) E. Darrah et al.   Science Translational Medicine

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

The rheumatoid arthritis synovial fluid citrullinome reveals novel citrullinated epitopes in apolipoprotein E, myeloid nuclear differentiation antigen, and β-actin

(2012) Joyce J. B. C. van Beers et al.   ARTHRITIS AND RHEUMATISM

Presence and Role of Anti-Citrullinated Protein Antibodies in Experimental Arthritis Models

(2012) Tineke Cantaert et al.   ARTHRITIS AND RHEUMATISM

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

(2012) Ulrike Harre et al.   JOURNAL OF CLINICAL INVESTIGATION

Heterogeneity of Anticitrullinated Peptide Antibodies and Response to Anti-Tumor Necrosis Factor Agents in Rheumatoid Arthritis

(2012) B. A. FISHER et al.   JOURNAL OF RHEUMATOLOGY

Antibodies to citrullinated  -enolase peptide 1 and clinical and radiological outcomes in rheumatoid arthritis

(2011) B. A. Fisher et al.   ANNALS OF THE RHEUMATIC DISEASES

The ACPA recognition profile and subgrouping of ACPA-positive RA patients

(2011) Annemiek Willemze et al.   ANNALS OF THE RHEUMATIC DISEASES

Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis

(2011) H. U. Scherer et al.   ANNALS OF THE RHEUMATIC DISEASES

B cell activation biomarkers as predictive factors for the response to rituximab in rheumatoid arthritis: A six-month, national, multicenter, open-label study

(2011) Jérémie Sellam et al.   ARTHRITIS AND RHEUMATISM

Development of the anti-citrullinated protein antibody repertoire prior to the onset of rheumatoid arthritis

(2011) Lotte A. van de Stadt et al.   ARTHRITIS AND RHEUMATISM

Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis

(2011) P. Suwannalai et al.   ARTHRITIS AND RHEUMATISM

Carbamylation-Derived Products: Bioactive Compounds and Potential Biomarkers in Chronic Renal Failure and Atherosclerosis

(2011) S. Jaisson et al.   CLINICAL CHEMISTRY

Genetics of rheumatoid arthritis: what have we learned?

(2011) Marieke Bax et al.   IMMUNOGENETICS

Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells

(2011) Jamie M. Ireland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

(2011) J. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibodies of IgG, IgA and IgM isotypes against cyclic citrullinated peptide precede the development of rheumatoid arthritis

(2011) Heidi Kokkonen et al.   ARTHRITIS RESEARCH & THERAPY

Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis

(2010) D. van der Woude et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-citrullinated protein antibodies have a low avidity compared with antibodies against recall antigens

(2010) P. Suwannalai et al.   ANNALS OF THE RHEUMATIC DISEASES

The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia

(2010) L. A. van de Stadt et al.   ANNALS OF THE RHEUMATIC DISEASES

The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis

(2010) D. van der Woude et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities

(2010) A. Ioan-Facsinay et al.   ANNALS OF THE RHEUMATIC DISEASES

2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) D. Aletaha et al.   ANNALS OF THE RHEUMATIC DISEASES

Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis

(2010) Jason R. Kolfenbach et al.   ARTHRITIS AND RHEUMATISM

Anticitrulline antibodies can be caused by homocitrulline-containing proteins in rabbits

(2010) Sanna Turunen et al.   ARTHRITIS AND RHEUMATISM

Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: A meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein

(2010) Diane van der Woude et al.   ARTHRITIS AND RHEUMATISM

Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid

(2010) Hans U. Scherer et al.   ARTHRITIS AND RHEUMATISM

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

(2010) Pingxin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Carbamylation-Dependent Activation of T Cells: A Novel Mechanism in the Pathogenesis of Autoimmune Arthritis

(2010) P. Mydel et al.   JOURNAL OF IMMUNOLOGY

Rheumatoid arthritis

(2010) David L Scott et al.   LANCET

Arthritis development in patients with arthralgia is strongly associated with anti-citrullinated protein antibody status: a prospective cohort study

(2009) W. H. Bos et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

(2009) L. A. Trouw et al.   ARTHRITIS AND RHEUMATISM

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis

(2009) Hüseyin Uysal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pretreatment serum levels of anti-cyclic citrullinated peptide antibodies are associated with the response to methotrexate in recent-onset arthritis

(2008) K Visser et al.   ANNALS OF THE RHEUMATIC DISEASES

Serum IgG antibodies to peptidylarginine deiminase 4 predict radiographic progression in patients with rheumatoid arthritis treated with tumour necrosis factor-  blocking agents

(2008) E H Halvorsen et al.   ANNALS OF THE RHEUMATIC DISEASES

The Immunopathogenesis of Rheumatoid Arthritis

(2008) John B. Imboden   Annual Review of Pathology-Mechanisms of Disease

Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis

(2008) Michelle L. Harris et al.   ARTHRITIS AND RHEUMATISM

Progression of joint damage in early rheumatoid arthritis: Association with HLA–DRB1, rheumatoid factor, and anti–citrullinated protein antibodies in relation to different treatment strategies

(2008) J. K. de Vries-Bouwstra et al.   ARTHRITIS AND RHEUMATISM

Marked differences in fine specificity and isotype usage of the anti-citrullinated protein antibody in health and disease

(2008) Andreea Ioan-Facsinay et al.   ARTHRITIS AND RHEUMATISM

Induction of macrophage secretion of tumor necrosis factor α through Fcγ receptor IIa engagement by rheumatoid arthritis–specific autoantibodies to citrullinated proteins complexed with fibrinogen

(2008) Cyril Clavel et al.   ARTHRITIS AND RHEUMATISM

Detecting shared pathogenesis from the shared genetics of immune-related diseases

(2008) Alexandra Zhernakova et al.   NATURE REVIEWS GENETICS

Immunoglobulin 1 (IgG1) Fc-glycosylation profiling of anti-citrullinated peptide antibodies from human serum

(2008) H. Ulrich Scherer et al.   Proteomics Clinical Applications