A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

Imaging-Based High-Throughput Screening Assay To Identify New Molecules with Transmission-Blocking Potential against Plasmodium falciparum Female Gamete Formation

(2015) Celia Miguel-Blanco et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A combination of new screening assays for prioritization of transmission-blocking antimalarials reveals distinct dynamics of marketed and experimental drugs

(2015) J. M. Bolscher et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Multicolor Bioluminescence Boosts Malaria Research: Quantitative Dual-Color Assay and Single-Cell Imaging in Plasmodium falciparum Parasites

(2014) Luca Cevenini et al.   ANALYTICAL CHEMISTRY

Effect of Fluorescent Dyes onIn Vitro-Differentiated, Late-Stage Plasmodium falciparum Gametocytes

(2014) Tamirat Gebru et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Male and Female Gametocyte Functional Viability Assay To Identify Biologically Relevant Malaria Transmission-Blocking Drugs

(2014) A. Ruecker et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Scalable Assessment of Plasmodium falciparum Transmission in the Standard Membrane-Feeding Assay, Using Transgenic Parasites Expressing Green Fluorescent Protein–Luciferase

(2014) Will J. R. Stone et al.   JOURNAL OF INFECTIOUS DISEASES

A Flow Cytometry-Based Quantitative Drug Sensitivity Assay for All Plasmodium falciparum Gametocyte Stages

(2014) Zenglei Wang et al.   PLoS One

Gametocytocidal Screen Identifies Novel Chemical Classes with Plasmodium falciparum Transmission Blocking Activity

(2014) Natalie G. Sanders et al.   PLoS One

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

(2014) S. Mok et al.   SCIENCE

Antiapicoplast and Gametocytocidal Screening To Identify the Mechanisms of Action of Compounds within the Malaria Box

(2013) Jessica D. Bowman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay

(2013) Leonardo Lucantoni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Male and Female Plasmodium falciparum Mature Gametocytes Show Different Responses to Antimalarial Drugs

(2013) Michael J. Delves et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection

(2013) Sarah D'Alessandro et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Identification of inhibitors of Plasmodium falciparum gametocyte development

(2013) Sandra Duffy et al.   MALARIA JOURNAL

Plasmodium falciparum gametocytes: with a view to a kill

(2013) ALICE S. BUTTERWORTH et al.   PARASITOLOGY

The Open Access Malaria Box: A Drug Discovery Catalyst for Neglected Diseases

(2013) Thomas Spangenberg et al.   PLoS One

Development and Optimization of a Novel 384-Well Anti-Malarial Imaging Assay Validated for High-Throughput Screening

(2012) Sandra Duffy et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

In VitroActivity of Fluorescent Dyes against Asexual Blood Stages of Plasmodium falciparum

(2012) Fanny Joanny et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activity of Clinically Relevant Antimalarial Drugs on Plasmodium falciparum Mature Gametocytes in an ATP Bioluminescence “Transmission Blocking” Assay

(2012) Joël Lelièvre et al.   PLoS One

The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites

(2012) Michael Delves et al.   PLOS MEDICINE

Vector control: a cornerstone in the malaria elimination campaign

(2011) K. Karunamoorthi   CLINICAL MICROBIOLOGY AND INFECTION

Epidemiology and Infectivity of Plasmodium falciparum and Plasmodium vivax Gametocytes in Relation to Malaria Control and Elimination

(2011) T. Bousema et al.   CLINICAL MICROBIOLOGY REVIEWS

Drug-resistant malaria: Molecular mechanisms and implications for public health

(2011) Ines Petersen et al.   FEBS LETTERS

A malaria gametocytocidal assay using oxidoreduction indicator, alamarBlue

(2011) Takeshi Q Tanaka et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

(2011) S. H. Adjalley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Coming-Out of Malaria Gametocytes

(2010) Andrea Kuehn et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Flow cytometry for the evaluation of anti-plasmodial activity of drugs on Plasmodium falciparum gametocytes

(2010) Severine Chevalley et al.   MALARIA JOURNAL

Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs

(2010) Teun Bousema et al.   MALARIA JOURNAL

Promiscuous Expression of α-Tubulin II in Maturing Male and Female Plasmodium falciparum Gametocytes

(2010) Samana Schwank et al.   PLoS One

The Malaria Parasite Cyclic GMP-Dependent Protein Kinase Plays a Central Role in Blood-Stage Schizogony

(2009) Helen M. Taylor et al.   EUKARYOTIC CELL

Effect of Antimalarial Drugs onPlasmodium falciparumGametocytes

(2009) Christopher L. Peatey et al.   JOURNAL OF INFECTIOUS DISEASES

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Disruption of aPlasmodium falciparumcyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis

(2008) Cathy J. Taylor et al.   MOLECULAR MICROBIOLOGY

Gametogenesis in Malaria Parasites Is Mediated by the cGMP-Dependent Protein Kinase

(2008) Louisa McRobert et al.   PLOS BIOLOGY