Compensatory T-type Ca2+ channel activity alters D2-autoreceptor responses of Substantia nigra dopamine neurons from Cav1.3 L-type Ca2+ channel KO mice

Location matters: somatic and dendritic SK channels answer to distinct calcium signals

(2015) Stephanie Rudolph et al.   JOURNAL OF NEUROPHYSIOLOGY

Gating of dopamine transmission by calcium and axonal N-, Q-, T- and L-type voltage-gated calcium channels differs between striatal domains

(2015) Katherine R. Brimblecombe et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dopamine midbrain neurons in health and Parkinson’s disease: Emerging roles of voltage-gated calcium channels and ATP-sensitive potassium channels

(2015) E. Dragicevic et al.   NEUROSCIENCE

C-Terminal Modulatory Domain Controls Coupling of Voltage-Sensing to Pore Opening in Cav1.3 L-type Ca2+ Channels

(2014) Andreas Lieb et al.   BIOPHYSICAL JOURNAL

Calcium currents regulate dopamine autoreceptors

(2014) Anders Borgkvist et al.   BRAIN

Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons

(2014) Elena Dragicevic et al.   BRAIN

Regulation of Gene Transcription by Voltage-gated L-type Calcium Channel, Cav1.3

(2014) Ling Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aging Decreases L-Type Calcium Channel Currents and Pacemaker Firing Fidelity in Substantia Nigra Dopamine Neurons

(2014) S. Y. Branch et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase

(2014) Javier Sanchez-Padilla et al.   NATURE NEUROSCIENCE

Neuronal Voltage-Gated Calcium Channels: Structure, Function, and Dysfunction

(2014) Brett A. Simms et al.   NEURON

Specific needs of dopamine neurons for stimulation in order to survive: implication for Parkinson disease

(2013) Patrick P. Michel et al.   FASEB JOURNAL

Different Calcium Sources Control Somatic versus Dendritic SK Channel Activation during Action Potentials

(2013) S. L. Jones et al.   JOURNAL OF NEUROSCIENCE

Phase II safety, tolerability, and dose selection study of isradipine as a potential disease-modifying intervention in early Parkinson's disease (STEADY-PD)

(2013)   MOVEMENT DISORDERS

Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production

(2013) Rachel A. Rice et al.   NEUROBIOLOGY OF AGING

Use of Calcium Channel Blockers and Parkinson’s Disease

(2012) Björn Pasternak et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Neuronal vulnerability, pathogenesis, and Parkinson's disease

(2012) David Sulzer et al.   MOVEMENT DISORDERS

T-Type Calcium Channel Blockers That Attenuate Thalamic Burst Firing and Suppress Absence Seizures

(2012) E. Tringham et al.   Science Translational Medicine

CaV1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease

(2012) Soosung Kang et al.   Nature Communications

L-type calcium channel auto-regulation of transcription

(2011) Jonathan Satin et al.   CELL CALCIUM

Dopamine Receptor Interacting Proteins: Targeting Neuronal Calcium Sensor-1/D2 Dopamine Receptor Interaction for Antipsychotic Drug Development

(2011) Nadine Kabbani et al.   CURRENT DRUG TARGETS

The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease

(2011) E. Ilijic et al.   NEUROBIOLOGY OF DISEASE

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

How Modeling Can Reconcile Apparently Discrepant Experimental Results: The Case of Pacemaking in Dopaminergic Neurons

(2011) Guillaume Drion et al.   PLoS Computational Biology

Ageing, neurodegeneration and Parkinson's disease

(2010) J. V. Hindle   AGE AND AGEING

The Origins of Oxidant Stress in Parkinson's Disease and Therapeutic Strategies

(2010) Dalton James Surmeier et al.   ANTIOXIDANTS & REDOX SIGNALING

Contributions of T-type calcium channel isoforms to neuronal firing

(2010) Stuart M. Cain et al.   Channels

Hyperexcitable Substantia Nigra Dopamine Neurons in PINK1- and HtrA2/Omi-Deficient Mice

(2010) Matthew W. Bishop et al.   JOURNAL OF NEUROPHYSIOLOGY

LEF1/ -Catenin Complex Regulates Transcription of the Cav3.1 Calcium Channel Gene (Cacna1g) in Thalamic Neurons of the Adult Brain

(2010) M. B. Wisniewska et al.   JOURNAL OF NEUROSCIENCE

Pacemaking in Dopaminergic Ventral Tegmental Area Neurons: Depolarizing Drive from Background and Voltage-Dependent Sodium Conductances

(2010) Z. M. Khaliq et al.   JOURNAL OF NEUROSCIENCE

Cav1.3 and BK Channels for Timing and Regulating Cell Firing

(2010) David Henry Vandael et al.   MOLECULAR NEUROBIOLOGY

Tolerability of isradipine in early Parkinson's disease: A pilot dose escalation study

(2010) Tanya Simuni et al.   MOVEMENT DISORDERS

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

(2010) Jaime N. Guzman et al.   NATURE

Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease

(2010) Christian Lüscher et al.   NATURE REVIEWS NEUROSCIENCE

Neuronal Calcium Sensor-1 (Ncs1p) Is Up-regulated by Calcineurin to Promote Ca2+Tolerance in Fission Yeast

(2009) Nobuko Hamasaki-Katagiri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous Calcium Buffering Capacity of Substantia Nigral Dopamine Neurons

(2009) R. C. Foehring et al.   JOURNAL OF NEUROPHYSIOLOGY

Robust Pacemaking in Substantia Nigra Dopaminergic Neurons

(2009) J. N. Guzman et al.   JOURNAL OF NEUROSCIENCE

Cav1.3 Channel Voltage Dependence, Not Ca2+ Selectivity, Drives Pacemaker Activity and Amplifies Bursts in Nigral Dopamine Neurons

(2009) I. Putzier et al.   JOURNAL OF NEUROSCIENCE

NCS-1 in the Dentate Gyrus Promotes Exploration, Synaptic Plasticity, and Rapid Acquisition of Spatial Memory

(2009) Bechara J. Saab et al.   NEURON

Molecular and cellular basis of small- and intermediate-conductance, calcium-activated potassium channel function in the brain

(2008) P. Pedarzani et al.   CELLULAR AND MOLECULAR LIFE SCIENCES