Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium

Dickkopf-1, the Wnt antagonist, is induced by acidic pH and mediates epithelial cellular senescence in human reflux esophagitis

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Sulforaphane Accelerates Acetaldehyde Metabolism by Inducing Aldehyde Dehydrogenases: Relevance to Ethanol Intolerance

(2013) Yusuke Ushida et al.   ALCOHOL AND ALCOHOLISM

Acetaldehyde and the genome: Beyond nuclear DNA adducts and carcinogenesis

(2013) Philip J. Brooks et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Loss of SMAD4 From Colorectal Cancer Cells Promotes CCL15 Expression to Recruit CCR1+ Myeloid Cells and Facilitate Liver Metastasis

(2013) Yoshiro Itatani et al.   GASTROENTEROLOGY

Oesophageal carcinoma

(2013) Arjun Pennathur et al.   LANCET

Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde-derived DNA damage in the blood of Japanese alcoholics

(2012) Yoshiyuki Yukawa et al.   CANCER SCIENCE

ALDH2 Activator Inhibits Increased Myocardial Infarction Injury by Nitroglycerin Tolerance

(2011) L. Sun et al.   Science Translational Medicine

Formation of acetaldehyde-derived DNA adducts due to alcohol exposure

(2010) Hsu-Sheng Yu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

NOTCH1 and NOTCH3 Coordinate Esophageal Squamous Differentiation Through a CSL-Dependent Transcriptional Network

(2010) Shinya Ohashi et al.   GASTROENTEROLOGY

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

Functional Variants in ADH1B and ALDH2 Coupled With Alcohol and Smoking Synergistically Enhance Esophageal Cancer Risk

(2009) Ri Cui et al.   GASTROENTEROLOGY

Aldehyde Dehydrogenase 2 Ameliorates Acute Cardiac Toxicity of Ethanol

(2009) Heng Ma et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A review of human carcinogens—Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish

(2009) Béatrice Secretan et al.   LANCET ONCOLOGY

The Alcohol Flushing Response: An Unrecognized Risk Factor for Esophageal Cancer from Alcohol Consumption

(2009) Philip J Brooks et al.   PLOS MEDICINE

Salivary Acetaldehyde Concentration According to Alcoholic Beverage Consumed and Aldehyde Dehydrogenase-2 Genotype

(2008) Akira Yokoyama et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Histone H2AX phosphorylation as a molecular pharmacological marker for DNA interstrand crosslink cancer chemotherapy

(2008) P.H. Clingen et al.   BIOCHEMICAL PHARMACOLOGY

Increased formation of gastric N2-ethylidene-2′-deoxyguanosine DNA adducts in aldehyde dehydrogenase-2 knockout mice treated with ethanol

(2008) Haruna Nagayoshi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

(2008) Che-Hong Chen et al.   SCIENCE