Sox2-CreER mice are useful for fate mapping of mature, but not neonatal, cochlear supporting cells in hair cell regeneration studies

DNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cells

(2016) Maarja Laos et al.   Aging-US

Gene Expression by Mouse Inner Ear Hair Cells during Development

(2015) D. I. Scheffer et al.   JOURNAL OF NEUROSCIENCE

Characterization of the Transcriptome of Nascent Hair Cells and Identification of Direct Targets of the Atoh1 Transcription Factor

(2015) T. Cai et al.   JOURNAL OF NEUROSCIENCE

Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea

(2015) Juan C. Maass et al.   Frontiers in Cellular Neuroscience

Lgr5+ cells regenerate hair cells via proliferation and direct transdifferentiation in damaged neonatal mouse utricle

(2015) Tian Wang et al.   Nature Communications

Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo

(2014) B. C. Cox et al.   DEVELOPMENT

Sensory hair cell regeneration in the zebrafish lateral line

(2014) Mark E Lush et al.   DEVELOPMENTAL DYNAMICS

 -Catenin Is Required for Hair-Cell Differentiation in the Cochlea

(2014) F. Shi et al.   JOURNAL OF NEUROSCIENCE

Auditory Hair Cell-Specific Deletion of p27Kip1 in Postnatal Mice Promotes Cell-Autonomous Generation of New Hair Cells and Normal Hearing

(2014) B. J. Walters et al.   JOURNAL OF NEUROSCIENCE

In Vivo Generation of Immature Inner Hair Cells in Neonatal Mouse Cochleae by Ectopic Atoh1 Expression

(2014) Zhiyong Liu et al.   PLoS One

HMGA2, the Architectural Transcription Factor High Mobility Group, Is Expressed in the Developing and Mature Mouse Cochlea

(2014) Ibtihel Smeti et al.   PLoS One

Hair Cell Regeneration after ATOH1 Gene Therapy in the Cochlea of Profoundly Deaf Adult Guinea Pigs

(2014) Patrick J. Atkinson et al.   PLoS One

Spontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse

(2014) Marcia M. Mellado Lagarde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway

(2014) Wenyan Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FGFR1-Frs2/3 Signalling Maintains Sensory Progenitors during Inner Ear Hair Cell Formation

(2014) Kazuya Ono et al.   PLoS Genetics

Lgr5-Positive Supporting Cells Generate New Hair Cells in the Postnatal Cochlea

(2014) Naomi F. Bramhall et al.   Stem Cell Reports

Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA

(2013) Xiaoping Du et al.   HEARING RESEARCH

Selective Ablation of Pillar and Deiters' Cells Severely Affects Cochlear Postnatal Development and Hearing in Mice

(2013) M. M. Mellado Lagarde et al.   JOURNAL OF NEUROSCIENCE

Insulin-like growth factor 1 inhibits hair cell apoptosis and promotes the cell cycle of supporting cells by activating different downstream cascades after pharmacological hair cell injury in neonatal mice

(2013) Yushi Hayashi et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Notch Inhibition Induces Cochlear Hair Cell Regeneration and Recovery of Hearing after Acoustic Trauma

(2013) Kunio Mizutari et al.   NEURON

In Vivo Visualization of Notch1 Proteolysis Reveals the Heterogeneity of Notch1 Signaling Activity in the Mouse Cochlea

(2013) Zhiyong Liu et al.   PLoS One

Notch Signaling Limits Supporting Cell Plasticity in the Hair Cell-Damaged Early Postnatal Murine Cochlea

(2013) Soumya Korrapati et al.   PLoS One

Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors

(2013) Fuxin Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cotransfection of Pax2 and Math1 promote in situ cochlear hair cell regeneration after neomycin insult

(2013) Yan Chen et al.   Scientific Reports

A dual function for canonical Wnt/ -catenin signaling in the developing mammalian cochlea

(2012) B. E. Jacques et al.   DEVELOPMENT

In vivo notch reactivation in differentiating cochlear hair cells induces sox2 and prox1 expression but does not disrupt hair cell maturation

(2012) Zhiyong Liu et al.   DEVELOPMENTAL DYNAMICS

Conditional Gene Expression in the Mouse Inner Ear Using Cre-loxP

(2012) Brandon C. Cox et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Regulation of p27Kip1 by Sox2 Maintains Quiescence of Inner Pillar Cells in the Murine Auditory Sensory Epithelium

(2012) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

Age-Dependent In Vivo Conversion of Mouse Cochlear Pillar and Deiters' Cells to Immature Hair Cells by Atoh1 Ectopic Expression

(2012) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

Atoh1 Directs the Formation of Sensory Mosaics and Induces Cell Proliferation in the Postnatal Mammalian Cochlea In Vivo

(2012) M. C. Kelly et al.   JOURNAL OF NEUROSCIENCE

A Novel Atoh1 “Self-Terminating” Mouse Model Reveals the Necessity of Proper Atoh1 Level and Duration for Hair Cell Differentiation and Viability

(2012) Ning Pan et al.   PLoS One

Regeneration of Stereocilia of Hair Cells by Forced Atoh1 Expression in the Adult Mammalian Cochlea

(2012) Shi-Ming Yang et al.   PLoS One

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

(2012) R. Chai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p27Kip1is required to maintain proliferative quiescence in the adult cochlea and pituitary

(2011) Elizabeth C. Oesterle et al.   CELL CYCLE

Sox2+ Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice

(2011) Katrin Arnold et al.   Cell Stem Cell

Atoh1 induces auditory hair cell recovery in mice after ototoxic injury

(2011) Shannon Kraft et al.   LARYNGOSCOPE

Growth Hormone Promotes Hair Cell Regeneration in the Zebrafish (Danio rerio) Inner Ear following Acoustic Trauma

(2011) Huifang Sun et al.   PLoS One

Differential and overlapping expression pattern of SOX2 and SOX9 in inner ear development

(2009) Angel C.Y. Mak et al.   GENE EXPRESSION PATTERNS

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea

(2008) A. Dabdoub et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA