Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment

TNF-α and Th2 Cytokines Induce Atopic Dermatitis–Like Features on Epidermal Differentiation Proteins and Stratum Corneum Lipids in Human Skin Equivalents

(2014) Mogbekeloluwa O. Danso et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

LC–MS Metabolomics of Psoriasis Patients Reveals Disease Severity-Dependent Increases in Circulating Amino Acids That Are Ameliorated by Anti-TNFα Treatment

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Oral ponesimod in patients with chronic plaque psoriasis: a randomised, double-blind, placebo-controlled phase 2 trial

(2014) Andrea Vaclavkova et al.   LANCET

Hexosylceramides as intrathecal markers of worsening disability in multiple sclerosis

(2014) Antonio Checa et al.   Multiple Sclerosis Journal

The important role of stratum corneum lipids for the cutaneous barrier function

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NF-κB and STAT3 Inhibition as a Therapeutic Strategy in Psoriasis: In Vitro and In Vivo Effects of BTH

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Incidence of Cardiovascular Disease in Individuals with Psoriasis: A Systematic Review and Meta-Analysis

(2013) Eleanor J. Samarasekera et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Psoriasis Is Not Associated with Atherosclerosis and Incident Cardiovascular Events: The Rotterdam Study

(2013) Emmilia A. Dowlatshahi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Interferon-γ Decreases Ceramides with Long-Chain Fatty Acids: Possible Involvement in Atopic Dermatitis and Psoriasis

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Ceramides in the Skin Lipid Membranes: Length Matters

(2013) Barbora Školová et al.   LANGMUIR

Abnormal lipoprotein particles and cholesterol efflux capacity in patients with psoriasis

(2012) Nehal N. Mehta et al.   ATHEROSCLEROSIS

Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

(2012) Jie Liang et al.   CANCER CELL

Sphingolipid Signaling in Metabolic Disorders

(2012) Timothy Hla et al.   Cell Metabolism

Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients

(2012) Michelle Janssens et al.   JOURNAL OF LIPID RESEARCH

Bioactive lipid mediators in skin inflammation and immunity

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Analysis of mammalian sphingolipids by liquid chromatography tandem mass spectrometry (LC-MS/MS) and tissue imaging mass spectrometry (TIMS)

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Sphingosine 1-phosphate (S1P): Physiology and the effects of S1P receptor modulation

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Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

(2011) C. Christoffersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sphingosine 1-phosphate in coagulation and inflammation

(2011) Hideru Obinata et al.   Seminars in Immunopathology

Sphingosine 1-phosphate levels in plasma and HDL are altered in coronary artery disease

(2010) Katherine J. E. Sattler et al.   BASIC RESEARCH IN CARDIOLOGY

Effect of ceramide acyl chain length on skin permeability and thermotropic phase behavior of model stratum corneum lipid membranes

(2010) Barbora Janůšová et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Effects of the novel immunosuppressant FTY720 in a murine rheumatoid arthritis model

(2010) Sachi Tsunemi et al.   CLINICAL IMMUNOLOGY

C-Myc is a Nrf2-interacting protein that negatively regulates phase II genes through their electrophile responsive elements

(2010) Smadar Levy et al.   IUBMB LIFE

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

(2010) Sergio E. Alvarez et al.   NATURE

Interplay between keratinocytes and immune cells—Recent insights into psoriasis pathogenesis

(2008) Giulia Tonel et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Characterization of overall ceramide species in humanstratum corneum

(2008) Yoshinori Masukawa et al.   JOURNAL OF LIPID RESEARCH