Variants in the Regulatory Region of WNT5A Reduced Risk of Cardiac Conotruncal Malformations in the Chinese Population

Loss of Wnt5a disrupts second heart field cell deployment and may contribute to OFT malformations in DiGeorge syndrome

(2014) Tanvi Sinha et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16

(2013) Heather J Cordell et al.   NATURE GENETICS

Cardiac outflow tract anomalies

(2013) Zachary Neeb et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Wnt5a and Wnt11 are essential for second heart field progenitor development

(2012) E. D. Cohen et al.   DEVELOPMENT

Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice

(2012) Elvira R.M. Bakker et al.   DEVELOPMENTAL BIOLOGY

Transcriptional Control in Cardiac Progenitors: Tbx1 Interacts with the BAF Chromatin Remodeling Complex and Regulates Wnt5a

(2012) Li Chen et al.   PLoS Genetics

Wnt5a: its signalling, functions and implication in diseases

(2011) A. Kikuchi et al.   Acta Physiologica

Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2

(2011) Bo Gao et al.   DEVELOPMENTAL CELL

Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls

(2011) Rachel Soemedi et al.   HUMAN MOLECULAR GENETICS

Birth Prevalence of Congenital Heart Disease Worldwide

(2011) Denise van der Linde et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Heterogeneity of Genetic Modifiers Ensures Normal Cardiac Development

(2010) Julia B. Winston et al.   CIRCULATION

The Multiple Phases and Faces of Wnt Signaling During Cardiac Differentiation and Development

(2010) Susanne Gessert et al.   CIRCULATION RESEARCH

Genetic factors in non-syndromic congenital heart malformations

(2010) MW Wessels et al.   CLINICAL GENETICS

Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors

(2010) L. Grumolato et al.   GENES & DEVELOPMENT

Signaling Pathways Controlling Second Heart Field Development

(2009) Francesca Rochais et al.   CIRCULATION RESEARCH

Wnt3a Regulates the Development of Cardiac Neural Crest Cells by Modulating Expression of Cysteine-Rich Intestinal Protein 2 in Rhombomere 6

(2008) Xiaojing Sun et al.   CIRCULATION RESEARCH