Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptor

Five amino acid residues in cysteine-rich domain of human T1R3 were involved in the response for sweet-tasting protein, thaumatin

(2013) Tetsuya Masuda et al.   BIOCHIMIE

Dissimilar sweet proteins from plants: Oddities or normal components?

(2012) Delia Picone et al.   PLANT SCIENCE

Identification and Modulation of the Key Amino Acid Residue Responsible for the pH Sensitivity of Neoculin, a Taste-Modifying Protein

(2011) Ken-ichiro Nakajima et al.   PLoS One

Key Amino Acid Residues Involved in Multi-Point Binding Interactions between Brazzein, a Sweet Protein, and the T1R2–T1R3 Human Sweet Receptor

(2010) Fariba M. Assadi-Porter et al.   JOURNAL OF MOLECULAR BIOLOGY

Improved side-chain torsion potentials for the Amber ff99SB protein force field

(2010) Kresten Lindorff-Larsen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Acid-induced sweetness of neoculin is ascribed to its pH-dependent agonistic-antagonistic interaction with human sweet taste receptor

(2008) Ken-ichiro Nakajima et al.   FASEB JOURNAL

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

P-LINCS:  A Parallel Linear Constraint Solver for Molecular Simulation

(2007) Berk Hess   Journal of Chemical Theory and Computation