Angiotensin-Converting Enzyme-Induced Activation of Local Angiotensin Signaling Is Required for Ascending Aortic Aneurysms in Fibulin-4-Deficient Mice

Dysregulated Renin–Angiotensin–Aldosterone System Contributes to Pulmonary Arterial Hypertension

(2012) Frances S. de Man et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Direct Angiotensin II Type 2 Receptor Stimulation in N ω -Nitro- l -Arginine-Methyl Ester–Induced Hypertension

(2012) Ludovit Paulis et al.   HYPERTENSION

Decreased aortic diameter and compliance precedes blood pressure increases in postnatal development of elastin-insufficient mice

(2011) Victoria P. Le et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin Type 2 Receptor Agonist Compound 21 Reduces Vascular Injury and Myocardial Fibrosis in Stroke-Prone Spontaneously Hypertensive Rats

(2011) Asia Rehman et al.   HYPERTENSION

The Ghent Marfan Trial — A randomized, double-blind placebo controlled trial with losartan in Marfan patients treated with β-blockers

(2011) Katarina Möberg et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

A Nonpeptide Angiotensin II Type 2 Receptor Agonist Does Not Attenuate Postmyocardial Infarction Left Ventricular Remodeling in Mice

(2011) Alexander B. Jehle et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis

(2011) Ingrid M B H van de Laar et al.   NATURE GENETICS

Lethal Osteogenesis Imperfecta–Like Condition with Cutis Laxa and Arterial Tortuosity in MZ Twins Due to a Homozygous Fibulin-4 Mutation

(2011) Lance K. Erickson et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

Impaired Vascular Contractility and Aortic Wall Degeneration in Fibulin-4 Deficient Mice: Effect of Angiotensin II Type 1 (AT1) Receptor Blockade

(2011) Els Moltzer et al.   PLoS One

Noncanonical TGF  Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

(2011) T. M. Holm et al.   SCIENCE

Angiotensin II Type 2 Receptor Signaling Attenuates Aortic Aneurysm in Mice Through ERK Antagonism

(2011) J. P. Habashi et al.   SCIENCE

New insights into angiotensin receptor actions: from blood pressure to aging

(2010) Johannes Stegbauer et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Non-peptide AT2-receptor agonists

(2010) U Muscha Steckelings et al.   CURRENT OPINION IN PHARMACOLOGY

Losartan therapy in adults with Marfan syndrome: study protocol of the multi-center randomized controlled COMPARE trial

(2010) Teodora Radonic et al.   Trials

Are There Effects of Renin–Angiotensin System Antagonists Beyond Blood Pressure Control?

(2009) George Bakris   AMERICAN JOURNAL OF CARDIOLOGY

Causes and histopathology of ascending aortic disease in children and young adults

(2009) Deepali Jain et al.   CARDIOVASCULAR PATHOLOGY

Reduced Vessel Elasticity Alters Cardiovascular Structure and Function in Newborn Mice

(2009) Jessica E. Wagenseil et al.   CIRCULATION RESEARCH

Fibulin-4 Deficiency Results in Ascending Aortic Aneurysms

(2009) Jianbin Huang et al.   CIRCULATION RESEARCH

Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase

(2009) Masahito Horiguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Basis of Thoracic Aortic Aneurysms and Dissections: Focus on Smooth Muscle Cell Contractile Dysfunction

(2008) Dianna M. Milewicz et al.   Annual Review of Genomics and Human Genetics

Pulsatile Mechanical Pressure Promotes Angiotensin-Converting Enzyme Expression in Aortic Smooth Muscle Cells

(2008) Kenji Iizuka et al.   CARDIOVASCULAR DRUGS AND THERAPY

Angiotensin II Type 2 Receptor Stimulation

(2008) Elena Kaschina et al.   CIRCULATION