Blocking Macrophage Leukotriene B4 Prevents Endothelial Injury and Reverses Pulmonary Hypertension

Sodium Tanshinone IIA Sulfonate Inhibits Canonical Transient Receptor Potential Expression in Pulmonary Arterial Smooth Muscle from Pulmonary Hypertensive Rats

(2013) Jian Wang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pulmonary artery smooth muscle cell proliferation and migration in fetal lambs acclimatized to high-altitude long-term hypoxia: role of histone acetylation

(2012) Qiwei Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Immune and Inflammatory Cell Involvement in the Pathology of Idiopathic Pulmonary Arterial Hypertension

(2012) Rajkumar Savai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Balance between Regulatory T and Th17 Cells in Systemic Lupus Erythematosus: The Old and the New

(2012) Alessia Alunno et al.   Clinical & Developmental Immunology

Leptin and regulatory T-lymphocytes in idiopathic pulmonary arterial hypertension

(2012) Alice Huertas et al.   EUROPEAN RESPIRATORY JOURNAL

Early Macrophage Recruitment and Alternative Activation Are Critical for the Later Development of Hypoxia-Induced Pulmonary Hypertension

(2011) Eleni Vergadi et al.   CIRCULATION

Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension

(2011) Rasa Tamosiuniene et al.   CIRCULATION RESEARCH

The Role of Inflammation and Autoimmunity in the Pathophysiology of Pulmonary Arterial Hypertension

(2011) Nada Kherbeck et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways

(2011) Vinicio A. de Jesus Perez et al.   JOURNAL OF CELL BIOLOGY

Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival

(2011) Tero-Pekka Alastalo et al.   JOURNAL OF CLINICAL INVESTIGATION

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

(2011) Anca Sindrilaru et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms of disease: pulmonary arterial hypertension

(2011) Ralph T. Schermuly et al.   Nature Reviews Cardiology

Leukotriene A4Hydrolase Inhibition Attenuates Allergic Airway Inflammation and Hyperresponsiveness

(2010) Navin L. Rao et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Central Role for CD68(+) Macrophages in Hepatopulmonary Syndrome

(2010) Thenappan Thenappan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis

(2010) Olof Rådmark et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intrapulmonary Administration of Leukotriene B4 Enhances Pulmonary Host Defense against Pneumococcal Pneumonia

(2010) P. Mancuso et al.   INFECTION AND IMMUNITY

Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis

(2010) Nobuyo Higashi-Kuwata et al.   ARTHRITIS RESEARCH & THERAPY

Leukotriene B4-induced changes in vascular permeability are mediated by neutrophil release of heparin-binding protein (HBP/CAP37/azurocidin)

(2009) Antonio Di Gennaro et al.   FASEB JOURNAL

Inflammation, Growth Factors, and Pulmonary Vascular Remodeling

(2009) Paul M. Hassoun et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Leukotriene B4 regulates proliferation and differentiation of cultured rat myoblasts via the BLT1 pathway

(2009) Ru Sun et al.   MOLECULES AND CELLS

Increased Frequency and Compromised Function of T Regulatory Cells in Systemic Sclerosis (SSc) Is Related to a Diminished CD69 and TGFβ Expression

(2009) Timothy R. D. J. Radstake et al.   PLoS One

The Cancer Paradigm of Severe Pulmonary Arterial Hypertension

(2008) Pradeep R. Rai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Phosphorylation of Serine 271 on 5-Lipoxygenase and Its Role in Nuclear Export

(2008) Nicolas Flamand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of vascular permeability by sphingosine 1-phosphate

(2008) Lichun Wang et al.   MICROVASCULAR RESEARCH