Pharmacogenomics and Patient Care: One Size Does Not Fit All

Current Trial-Associated Outcomes With Warfarin in Prevention of Stroke in Patients With Nonvalvular Atrial Fibrillation

(2012) Rory Hachamovitch   ARCHIVES OF INTERNAL MEDICINE

Risky Business: Risk Perception and the Use of Medical Services among Customers of DTC Personal Genetic Testing

(2012) David J. Kaufman et al.   Journal of Genetic Counseling

CYP2D6 Genotype and Tamoxifen Response in Postmenopausal Women with Endocrine-Responsive Breast Cancer: The Breast International Group 1-98 Trial

(2012) Meredith M. Regan et al.   JNCI-Journal of the National Cancer Institute

Biomarker Tests Need Closer Scrutiny, IOM Concludes

(2012) J. Kaiser   SCIENCE

Data-Driven Prediction of Drug Effects and Interactions

(2012) N. P. Tatonetti et al.   Science Translational Medicine

Detecting Drug Interactions From Adverse-Event Reports: Interaction Between Paroxetine and Pravastatin Increases Blood Glucose Levels

(2011) N P Tatonetti et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Phenotype Standardization Project: Improving Pharmacogenetic Studies of Serious Adverse Drug Reactions

(2011) M Pirmohamed et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacogenomics: “Noninferiority” Is Sufficient for Initial Implementation

(2011) R B Altman   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing

(2011) M V Relling et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing

(2011) J A Johnson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450-2C19 (CYP2C19) Genotype and Clopidogrel Therapy

(2011) S A Scott et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype

(2011) K R Crews et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

FKBP51 regulation of AKT/protein kinase B phosphorylation

(2011) Liewei Wang   CURRENT OPINION IN PHARMACOLOGY

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

(2011) M. Isabel Lucena et al.   GASTROENTEROLOGY

Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C

(2011) Yasuhito Tanaka et al.   HUMAN MOLECULAR GENETICS

HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

(2011) Mark McCormack et al.   NEW ENGLAND JOURNAL OF MEDICINE

A CFTR Potentiator in Patients with Cystic Fibrosis and theG551DMutation

(2011) Bonnie W. Ramsey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation

(2011) Heather E Wheeler et al.   PHARMACOGENOMICS

Using Multiple Microenvironments to Find Similar Ligand-Binding Sites: Application to Kinase Inhibitor Binding

(2011) Tianyun Liu et al.   PLoS Computational Biology

Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project

(2010) Rudolf Uher et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population

(2010) Takeshi Ozeki et al.   HUMAN MOLECULAR GENETICS

Genome-Wide Associations and Functional Genomic Studies of Musculoskeletal Adverse Events in Women Receiving Aromatase Inhibitors

(2010) James N. Ingle et al.   JOURNAL OF CLINICAL ONCOLOGY

ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C

(2010) Jacques Fellay et al.   NATURE

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

(2010) Kaixin Zhou et al.   NATURE GENETICS

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

Direct-to-consumer genome testing: opportunities for pharmacogenomics research?

(2010) Barbara Prainsack et al.   PHARMACOGENOMICS

Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations

(2010) Mathew J. Barber et al.   PLoS One

Genomewide Association Study of Movement-Related Adverse Antipsychotic Effects

(2009) Karolina Åberg et al.   BIOLOGICAL PSYCHIATRY

Pharmacogenetic testing of CYP2C9 and VKORC1 alleles for warfarin

(2009) David A Flockhart et al.   GENETICS IN MEDICINE

Association Between CYP2D6 Polymorphisms and Outcomes Among Women With Early Stage Breast Cancer Treated With Tamoxifen

(2009) Werner Schroth   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy

(2009) Alan R. Shuldiner   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic Testing Before Anticoagulation? A Systematic Review of Pharmacogenetic Dosing of Warfarin

(2009) Kirsten Neudoerffer Kangelaris et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Survey on warfarin pharmacogenetic testing among anticoagulation providers

(2009) Maha Kadafour et al.   PHARMACOGENOMICS

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

(2009) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose

(2008) G. M. Cooper et al.   BLOOD

Use of Pharmacogenetic and Clinical Factors to Predict the Therapeutic Dose of Warfarin

(2008) BF Gage et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacogenetics: From Bench to Byte

(2008) JJ Swen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

HLA-B*5701 Screening for Hypersensitivity to Abacavir

(2008) Simon Mallal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cytochrome P-450 Polymorphisms and Response to Clopidogrel

(2008) Jessica L. Mega et al.   NEW ENGLAND JOURNAL OF MEDICINE