Cell Carriage, Delivery, and Selective Replication of an Oncolytic Virus in Tumor in Patients

Clinical development directions in oncolytic viral therapy

(2011) R M Eager et al.   CANCER GENE THERAPY

Internalization of Oncolytic Reovirus by Human Dendritic Cell Carriers Protects the Virus from Neutralization

(2011) E. J. Ilett et al.   CLINICAL CANCER RESEARCH

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans

(2011) Caroline J. Breitbach et al.   NATURE

Recent deal highlights hopes for cancer-killing viruses

(2011) Jon Evans   NATURE MEDICINE

A Phase I Study of the Combination of Intravenous Reovirus Type 3 Dearing and Gemcitabine in Patients with Advanced Cancer

(2010) M. P. Lolkema et al.   CLINICAL CANCER RESEARCH

REO-10: A Phase I Study of Intravenous Reovirus and Docetaxel in Patients with Advanced Cancer

(2010) C. Comins et al.   CLINICAL CANCER RESEARCH

Clinical trials with oncolytic reovirus: Moving beyond phase I into combinations with standard therapeutics

(2010) K.J. Harrington et al.   CYTOKINE & GROWTH FACTOR REVIEWS

OPTIM trial: a Phase III trial of an oncolytic herpes virus encoding GM-CSF for unresectable stage III or IV melanoma

(2010) Howard L Kaufman et al.   Future Oncology

In situ detection of microRNAs in paraffin embedded, formalin fixed tissues and the co-localization of their putative targets

(2010) Gerard J. Nuovo   METHODS

Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Oncolysis and Replication

(2009) R. J. Prestwich et al.   CLINICAL CANCER RESEARCH

Reovirus-based therapy for cancer

(2009) Kevin Kelly et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity

(2009) E J Ilett et al.   GENE THERAPY

Intravenous administration of Reolysin®, a live replication competent RNA virus is safe in patients with advanced solid tumors

(2009) Radharani Gollamudi et al.   INVESTIGATIONAL NEW DRUGS

Redundant and Synergistic Mechanisms Control the Sequestration of Blood-born Adenovirus in the Liver

(2009) Nelson C Di Paolo et al.   MOLECULAR THERAPY

Cell Carriers for Oncolytic Viruses: Fed Ex for Cancer Therapy

(2009) Candice Willmon et al.   MOLECULAR THERAPY

A methodology for the combined in situ analyses of the precursor and mature forms of microRNAs and correlation with their putative targets

(2009) Gerard J Nuovo et al.   Nature Protocols

A Phase I Study of Intravenous Oncolytic Reovirus Type 3 Dearing in Patients with Advanced Cancer

(2008) L. Vidal et al.   CLINICAL CANCER RESEARCH

Enhanced In vitro and In vivo Cytotoxicity of Combined Reovirus and Radiotherapy

(2008) K. Twigger et al.   CLINICAL CANCER RESEARCH

Oncolytic viruses: a novel form of immunotherapy

(2008) Robin J Prestwich et al.   Expert Review of Anticancer Therapy

Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial

(2008) C L White et al.   GENE THERAPY

Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma

(2008) F Errington et al.   GENE THERAPY