1 Integrin Inhibition Elicits a Prometastatic Switch Through the TGF -miR-200-ZEB Network in E-Cadherin-Positive Triple-Negative Breast Cancer

Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β

(2013) Jenny G. Parvani et al.   MOLECULAR BIOLOGY OF THE CELL

Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination

(2012) Veerander P. S. Ghotra et al.   PLoS One

An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state

(2012) C. Polytarchou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model

(2012) Kim Moran-Jones et al.   Scientific Reports

Automated microinjection of cell-polymer suspensions in 3D ECM scaffolds for high-throughput quantitative cancer invasion screens

(2011) Hoa H. Truong et al.   BIOMATERIALS

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer

(2011) Michael K. Wendt et al.   MOLECULAR BIOLOGY OF THE CELL

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

(2011) Philip A. Gregory et al.   MOLECULAR BIOLOGY OF THE CELL

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

(2011) Manav Korpal et al.   NATURE MEDICINE

Cross Talk among TGF-  Signaling Pathways, Integrins, and the Extracellular Matrix

(2011) J. S. Munger et al.   Cold Spring Harbor Perspectives in Biology

Roles for the type III TGF-β receptor in human cancer

(2010) Catherine E. Gatza et al.   CELLULAR SIGNALLING

The α2β1 integrin is a metastasis suppressor in mouse models and human cancer

(2010) Norma E. Ramirez et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrins as therapeutic targets: lessons and opportunities

(2010) Dermot Cox et al.   NATURE REVIEWS DRUG DISCOVERY

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Adhesion signaling - crosstalk between integrins, Src and Rho

(2009) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

(2009) Silvia Giampieri et al.   NATURE CELL BIOLOGY

An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression

(2009) Jay S Desgrosellier et al.   NATURE MEDICINE

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrin  1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

(2009) T. Shibue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 1 Integrin Inhibition Dramatically Enhances Radiotherapy Efficacy in Human Breast Cancer Xenografts

(2008) C. C. Park et al.   CANCER RESEARCH

Inhibition of Metastatic Outgrowth from Single Dormant Tumor Cells by Targeting the Cytoskeleton

(2008) D. Barkan et al.   CANCER RESEARCH

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY