Huwe1-Mediated Ubiquitylation of Dishevelled Defines a Negative Feedback Loop in the Wnt Signaling Pathway
Published 2014 View Full Article
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Title
Huwe1-Mediated Ubiquitylation of Dishevelled Defines a Negative Feedback Loop in the Wnt Signaling Pathway
Authors
Keywords
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Journal
Science Signaling
Volume 7, Issue 317, Pages ra26-ra26
Publisher
American Association for the Advancement of Science (AAAS)
Online
2014-03-19
DOI
10.1126/scisignal.2004985
References
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Note: Only part of the references are listed.- Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants
- (2013) Magdalena J. Lorenowicz et al. CELLULAR SIGNALLING
- RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt- -Catenin Signaling
- (2013) C.-M. Cruciat et al. SCIENCE
- Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
- (2013) H Jung et al. Oncogenesis
- The E3 Ubiquitin Ligase ITCH Negatively Regulates Canonical Wnt Signaling by Targeting Dishevelled Protein
- (2012) W. Wei et al. MOLECULAR AND CELLULAR BIOLOGY
- The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans
- (2011) A J Ross et al. CELL DEATH AND DIFFERENTIATION
- Sequential Activation and Inactivation of Dishevelled in the Wnt/β-Catenin Pathway by Casein Kinases
- (2011) Ondrej Bernatik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion
- (2011) Martin Harterink et al. NATURE CELL BIOLOGY
- Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis
- (2011) H Nikki March et al. NATURE GENETICS
- A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription
- (2010) K. Ewan et al. CANCER RESEARCH
- Loss of the Tumor Suppressor CYLD Enhances Wnt/β-Catenin Signaling through K63-Linked Ubiquitination of Dvl
- (2010) Daniele V.F. Tauriello et al. MOLECULAR CELL
- COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
- (2010) S. A. Forbes et al. NUCLEIC ACIDS RESEARCH
- Dishevelled: The hub of Wnt signaling
- (2009) Chan Gao et al. CELLULAR SIGNALLING
- The N-Myc-DLL3 Cascade Is Suppressed by the Ubiquitin Ligase Huwe1 to Inhibit Proliferation and Promote Neurogenesis in the Developing Brain
- (2009) Xudong Zhao et al. DEVELOPMENTAL CELL
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Nonproteolytic Functions of Ubiquitin in Cell Signaling
- (2009) Zhijian J. Chen et al. MOLECULAR CELL
- Protein structure prediction on the Web: a case study using the Phyre server
- (2009) Lawrence A Kelley et al. Nature Protocols
- The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein
- (2008) Xudong Zhao et al. NATURE CELL BIOLOGY
- Imaging individual mRNA molecules using multiple singly labeled probes
- (2008) Arjun Raj et al. NATURE METHODS
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