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Title
Antidiabetic Sulfonylureas and cAMP Cooperatively Activate Epac2A
Authors
Keywords
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Journal
Science Signaling
Volume 6, Issue 298, Pages ra94-ra94
Publisher
American Association for the Advancement of Science (AAAS)
Online
2013-10-23
DOI
10.1126/scisignal.2004581
References
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Note: Only part of the references are listed.- Epac2 Mediates Cardiac β1-Adrenergic–Dependent Sarcoplasmic Reticulum Ca 2+ Leak and Arrhythmia
- (2013) Laëtitia Pereira et al. CIRCULATION
- -Cell-Specific Protein Kinase A Activation Enhances the Efficiency of Glucose Control by Increasing Acute-Phase Insulin Secretion
- (2013) K. A. Kaihara et al. DIABETES
- Spatial Control of Epac2 Activity by cAMP and Ca2+-Mediated Activation of Ras in Pancreatic Cells
- (2013) O. Idevall-Hagren et al. Science Signaling
- Epac2: a sulfonylurea receptor?
- (2012) Holger Rehmann BIOCHEMICAL SOCIETY TRANSACTIONS
- Mechanism of Intracellular cAMP Sensor Epac2 Activation
- (2011) Sheng Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exchange Protein Directly Activated by Cyclic AMP Isoform 2 Is Not a Direct Target of Sulfonylurea Drugs
- (2010) Tamara Tsalkova et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- cAMP inhibits modulation of airway smooth muscle phenotype via the exchange protein activated by cAMP (Epac) and protein kinase A
- (2010) Sara S Roscioni et al. BRITISH JOURNAL OF PHARMACOLOGY
- Exendin-4 Suppresses Src Activation and Reactive Oxygen Species Production in Diabetic Goto-Kakizaki Rat Islets in an Epac-Dependent Manner
- (2010) E. Mukai et al. DIABETES
- Sulfonylurea action re-revisited
- (2010) Susumu Seino et al. Journal of Diabetes Investigation
- Critical role of the N-terminal cyclic AMP-binding domain of Epac2 in its subcellular localization and function
- (2009) Manabu Niimura et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines
- (2009) Kevin M Woolfrey et al. NATURE NEUROSCIENCE
- The cAMP Sensor Epac2 Is a Direct Target of Antidiabetic Sulfonylurea Drugs
- (2009) C.-L. Zhang et al. SCIENCE
- Epac2: A Molecular Target for Sulfonylurea-Induced Insulin Release
- (2009) S. A. Hinke Science Signaling
- ASEDock-Docking Based on Alpha Spheres and Excluded Volumes
- (2008) Junichi Goto et al. Journal of Chemical Information and Modeling
- Role of the cAMP sensor Epac as a determinant of KATPchannel ATP sensitivity in human pancreatic β-cells and rat INS-1 cells
- (2008) Guoxin Kang et al. JOURNAL OF PHYSIOLOGY-LONDON
- Ras Is Required for the Cyclic AMP-Dependent Activation of Rap1 via Epac2
- (2008) C. Liu et al. MOLECULAR AND CELLULAR BIOLOGY
- Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
- (2008) Holger Rehmann et al. NATURE
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