Heteromeric MT1/MT2 Melatonin Receptors Modulate Photoreceptor Function

GPR179 Is Required for Depolarizing Bipolar Cell Function and Is Mutated in Autosomal-Recessive Complete Congenital Stationary Night Blindness

(2012) Neal S. Peachey et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human cytomegalovirus-encoded UL33 and UL78 heteromerize with host CCR5 and CXCR4 impairing their HIV coreceptor activity

(2012) K. Tadagaki et al.   BLOOD

Restructuring G-Protein- Coupled Receptor Activation

(2012) Martin Audet et al.   CELL

Melatonin: An underappreciated player in retinal physiology and pathophysiology

(2012) Gianluca Tosini et al.   EXPERIMENTAL EYE RESEARCH

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

(2012) Amélie Bonnefond et al.   NATURE GENETICS

Apo-Ghrelin Receptor Forms Heteromers with DRD2 in Hypothalamic Neurons and Is Essential for Anorexigenic Effects of DRD2 Agonism

(2012) Andras Kern et al.   NEURON

Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland

(2012) Sergio González et al.   PLOS BIOLOGY

Unidirectional Cross-Activation of GRPR by MOR1D Uncouples Itch and Analgesia Induced by Opioids

(2011) Xian-Yu Liu et al.   CELL

Trends in the exploitation of novel drug targets

(2011) Mathias Rask-Andersen et al.   NATURE REVIEWS DRUG DISCOVERY

Facilitation of μ-Opioid Receptor Activity by Preventing δ-Opioid Receptor-Mediated Codegradation

(2011) Shao-Qiu He et al.   NEURON

Removal of melatonin receptor type 1 increases intraocular pressure and retinal ganglion cells death in the mouse

(2011) Susana Alcantara-Contreras et al.   NEUROSCIENCE LETTERS

Localization of Melatonin Receptor 1 in Mouse Retina and Its Role in the Circadian Regulation of the Electroretinogram and Dopamine Levels

(2011) Anamika Sengupta et al.   PLoS One

Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects

(2010) Lin Pei et al.   NATURE MEDICINE

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

(2010) M. L. Dubocovich et al.   PHARMACOLOGICAL REVIEWS

Receptor heteromerization and drug discovery

(2010) Raphael Rozenfeld et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

G protein-coupled receptor hetero-dimerization: contribution to pharmacology and function

(2009) Graeme Milligan   BRITISH JOURNAL OF PHARMACOLOGY

Light-dependent translocation of arrestin in rod photoreceptors is signaled through a phospholipase C cascade and requires ATP

(2009) Wilda Orisme et al.   CELLULAR SIGNALLING

Oligomerization of G-protein-coupled receptors: A reality

(2009) Sergi Ferré et al.   CURRENT OPINION IN PHARMACOLOGY

Dimerization in GPCR mobility and signaling

(2009) Martin J Lohse   CURRENT OPINION IN PHARMACOLOGY

Inhibition of Heterotrimeric G Protein Signaling by a Small Molecule Acting on Gα Subunit

(2009) Mohammed Akli Ayoub et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

Melatonin modulates visual function and cell viability in the mouse retina via the MT1 melatonin receptor

(2009) K. Baba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?

(2008) R Jockers et al.   BRITISH JOURNAL OF PHARMACOLOGY

The PDZ Protein Mupp1 Promotes GiCoupling and Signaling of the Mt1Melatonin Receptor

(2008) Jean-Luc Guillaume et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melatonin potentiates rod signals to ON type bipolar cells in fish retina

(2008) Yong Ping et al.   JOURNAL OF PHYSIOLOGY-LONDON

Identification of a serotonin/glutamate receptor complex implicated in psychosis

(2008) Javier González-Maeso et al.   NATURE