4.7 Article

Persistent organochlorine compounds in fetal and maternal tissues: Evaluation of their potential influence on several indicators of fetal growth and health

Journal

SCIENCE OF THE TOTAL ENVIRONMENT
Volume 409, Issue 15, Pages 2888-2893

Publisher

ELSEVIER
DOI: 10.1016/j.scitotenv.2011.04.031

Keywords

Persistent organic pollutants; Prenatal exposure; Umbilical cord serum; Birth weight; Length of gestation

Ask authors/readers for more resources

Some organochlorine compounds, such as polychlorinated biphenyls (PCBs), have a tendency to bioaccumulate in humans and predators at the top of the food chain. We have recently confirmed the transplacental transfer of these compounds and the present study has been designed on the same material with the aim of investigating their potential health effects on newborns from 70 pregnant women, resident in a Northern Italy industrial town. Organochlorine compounds [namely, p,p'-dichlorodiphenyltrichloroethane (p,p'-DDT), p,p'-dichlorodiphenyldichloroethene (p,p'-DDE), hexachlorobenzene (HCB), and PCBs] have been analyzed both in cord and maternal serum, placenta, and maternal subcutaneous adipose tissue by GC-MSD. p,p'-DDT levels in the adipose tissue resulted significantly (p<0.05) related to birth length. Mothers of neonates born by preterm programmed caesarean delivery showed significantly (p<0.005 for both) higher serum p,p'-DDE serum concentrations and p,p'-DDT levels in the adipose tissue, as compared to mothers delivering at term. (C) 2011 Elsevier B.V. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Review Allergy

Systematic Review and Meta-analysis on the Association of Occupational Exposure to Free Crystalline Silica and Rheumatoid Arthritis

A. Morotti, I. Sollaku, F. Franceschini, I. Cavazzana, M. Fredi, E. Sala, G. De Palma

Summary: Occupational exposure to free crystalline silica and tobacco smoking are associated with an increased risk of rheumatoid arthritis, especially with an interaction in seropositive subjects. Further studies are needed to support this association.

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2022)

Article Immunology

SARS-CoV-2 Breakthrough Infections: Incidence and Risk Factors in a Large European Multicentric Cohort of Health Workers

Stefano Porru, Maria Grazia Lourdes Monaco, Gianluca Spiteri, Angela Carta, Maria Diletta Pezzani, Giuseppe Lippi, Davide Gibellini, Evelina Tacconelli, Ilaria Dalla Vecchia, Emma Sala, Emanuele Sansone, Giuseppe De Palma, Carlo Bonfanti, Massimo Lombardo, Luigina Terlenghi, Enrico Pira, Ihab Mansour, Maurizio Coggiola, Catalina Ciocan, Alessandro Godono, Adonina Tardon, Marta-Maria Rodriguez-Suarez, Guillermo Fernandez-Tardon, Francisco-Jose Jimeno-Demuth, Rafael-Vicente Castro-Delgado, Tania Iglesias Cabo, Maria Luisa Scapellato, Filippo Liviero, Angelo Moretto, Paola Mason, Sofia Pavanello, Anna Volpin, Luigi Vimercati, Silvio Tafuri, Luigi De Maria, Stefania Sponselli, Pasquale Stefanizzi, Antonio Caputi, Fabriziomaria Gobba, Alberto Modenese, Loretta Casolari, Denise Garavini, Cristiana D'Elia, Stefania Mariani, Francesca Larese Filon, Luca Cegolon, Corrado Negro, Federico Ronchese, Francesca Rui, Paola De Michieli, Nicola Murgia, Marco Dell'Omo, Giacomo Muzi, Tiziana Fiordi, Angela Gambelunghe, Ilenia Folletti, Dana Mates, Violeta Claudia Calota, Andra Neamtu, Ovidiu Perseca, Catalin Alexandru Staicu, Angelica Voinoiu, Eleonora Fabianova, Jana Beresova, Zora Kl'ocova Adamcakova, Roman Nedela, Anna Lesnakova, Jana Holcikova, Paolo Boffetta, Mahsa Abedini, Giorgia Ditano, Shuffield Seyram Asafo, Giovanni Visci, Francesco Saverio Violante, Carlotta Zunarelli, Giuseppe Verlato

Summary: This research investigated the incidence of SARS-CoV-2 breakthrough infections and their determinants in a large European cohort of over 60,000 health workers. The study found that age and previous infection significantly modified breakthrough infection rates, and previous SARS-CoV-2 infection and antibody titer were inversely related to the risk of breakthrough infection.

VACCINES (2022)

Article Biochemistry & Molecular Biology

Bi-Allelic Mutations in Zebrafish pank2 Gene Lead to Testicular Atrophy and Perturbed Behavior without Signs of Neurodegeneration

Luca Mignani, Daniela Zizioli, Deepak Khatri, Nicola Facchinello, Marco Schiavone, Giuseppe De Palma, Dario Finazzi

Summary: This research explores the phenotypic characteristics of PANK2 gene mutations in a zebrafish animal model, identifying higher vulnerability of selected cell and tissue types to pank2 deficiency. These findings provide important clues for better understanding and treating PKAN.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Environmental Sciences

Arsenic may be a carcinogenic determinant of a subset of gallbladder cancer: A pilot study

Giuseppe De Palma, Gonzalo Carrasco-Avino, Enrica Gilberti, Moris Cadei, Tatiana Pedrazzi, Ivan M. Gallegos Mendez, Alejandra Roman, Nicolas Demartines, Paolo Boffetta, Ismail Labgaa

Summary: Gallbladder cancer (GBC) is a deadly malignancy with limited treatment options. The role of arsenic (As) in GBC carcinogenesis is debated, and there are no data on As measurement in GBC samples. This pilot study measured As concentrations in GBC tissue samples compared to non-cancerous gallbladder (NCGB) samples and found higher levels of arsenic in GBC samples, suggesting a potential impact of arsenic on GBC and the need for further studies.

ENVIRONMENTAL RESEARCH (2023)

Article Biochemistry & Molecular Biology

Ceruloplasmin-Deficient Mice Show Dysregulation of Lipid Metabolism in Liver and Adipose Tissue Reduced by a Protein Replacement

Sara Raia, Antonio Conti, Alan Zanardi, Barbara Ferrini, Giulia Maria Scotti, Enrica Gilberti, Giuseppe De Palma, Samuel David, Massimo Alessio

Summary: This study investigates the role of ceruloplasmin in iron and lipid metabolism. It reveals that deficiency of ceruloplasmin leads to obesity, adipose tissue accumulation, liver iron deposition, and steatosis. Ceruloplasmin replacement therapy is found to be effective in limiting liver iron accumulation and steatosis.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Article Toxicology

HBM4EU chromates study-the measurement of hexavalent and trivalent chromium in exhaled breath condensate samples from occupationally exposed workers across Europe

Elizabeth Leese, Kate Jones, Beatrice Bocca, Radia Bousoumah, Argelia Castano, Karen S. Galea, Ivo Iavicoli, Marta Esteban Lopez, Veruscka Leso, Sophie Ndaw, Simo P. Porras, Flavia Ruggieri, Paul T. J. Scheepers, Tiina Santonen

Summary: The aim of this study was to investigate the practicality of using exhaled breath condensate (EBC) as a biological matrix for detecting and measuring hexavalent chromium (Cr(VI)) and trivalent chromium (Cr(III)) in occupational workers. EBC samples were collected from workers in various countries and analyzed using hyphenated chromatography systems with inductively coupled plasma - mass spectrometry (ICP-MS). The results showed that occupationally exposed workers had significantly higher levels of Cr(VI) and Cr(III) compared to the control group. Chrome platers had the highest levels of Cr(VI) in their EBC samples, and both Cr(VI) and Cr(III) levels increased significantly after working. This study suggests that EBC can be a valid and non-invasive biological matrix for assessing occupational exposure to Cr(VI) and Cr(III).

TOXICOLOGY LETTERS (2023)

Article Virology

Determinants of Anti-S Immune Response at 9 Months after COVID-19 Vaccination in a Multicentric European Cohort of Healthcare Workers-ORCHESTRA Project

Giulia Collatuzzo, Vittorio Lodi, Daniela Feola, Giuseppe De Palma, Emanuele Sansone, Emma Sala, Christian Janke, Noemi Castelletti, Stefano Porru, Gianluca Spiteri, Maria Grazia Lourdes Monaco, Francesca Larese Filon, Corrado Negro, Luca Cegolon, Jana Beresova, Eleonora Fabianova, Lucia A. Carrasco-Ribelles, Pere Toran-Monserrat, Marta Maria Rodriguez-Suarez, Guillermo Fernandez-Tardon, Shuffield S. Asafo, Giorgia Ditano, Mahsa Abedini, Paolo Boffetta

Summary: This study analyzed the antibody levels after 9 months of COVID-19 vaccination and identified factors influencing these levels. The results showed that antibody levels were associated with gender, age, time since vaccination, previous infection, number of vaccine doses, and vaccine type. Additionally, the study observed a declining trend in antibody levels over time.

VIRUSES-BASEL (2022)

Article Immunology

Temporal trends of COVID-19 antibodies in vaccinated healthcare workers undergoing repeated serological sampling: An individual-level analysis within 13 months in the ORCHESTRA cohort

Giulia Collatuzzo, Giuseppe De Palma, Francesco S. Violante, Stefano Porru, Francesca Larese Filon, Eleonora Fabianova, Concepcion Violan, Luigi Vimercati, Mihaela Leustean, Marta Maria Rodriguez-Suarez, Emanuele Sansone, Emma Sala, Carlotta Zunarelli, Vittorio Lodi, Maria Grazia Lourdes Monaco, Gianluca Spiteri, Corrado Negro, Jana Beresova, Lucia A. Carrasco-Ribelles, Silvio Tafuri, Shuffield S. Asafo, Giorgia Ditano, Mahsa Abedini, Paolo Boffetta

Summary: We investigated changes in serologic measurements after COVID-19 vaccination and found that age, infection, vaccine doses, time between doses and serologies, and vaccine type were associated with changes in serologic levels within 13 months.

FRONTIERS IN IMMUNOLOGY (2023)

Article Immunology

Immune Responses to SARS-CoV-2 Infection and Vaccine in a Big Italian COVID-19 Hospital: An 18-Month Follow-Up

Emanuele Sansone, Carlo Bonfanti, Emma Sala, Stefano Renzetti, Luigina Terlenghi, Alberto Matteelli, Mara Maria Tiraboschi, Tatiana Pedrazzi, Massimo Lombardo, Camillo Rossi, Anna Maria Indelicato, Arnaldo Caruso, Giuseppe De Palma

Summary: This study aims to assess the trends of anti-SARS-CoV-2 antibodies over a 9-month period after vaccination with an anti-SARS-CoV-2 vaccine in a COVID-19 hospital in Northern Italy. The results showed that vaccination significantly reduced the infection rate and elicited a specific humoral response that lasted throughout the observational period. Pre-vaccine infection, especially during the first wave of the pandemic, greatly enhanced the response to vaccination, which was also influenced by age.

VACCINES (2023)

Article Immunology

The Effect of the Immunization Schedule and Antibody Levels (Anti-S) on the Risk of SARS-CoV-2 Infection in a Large Cohort of Healthcare Workers in Northern Italy

Emanuele Sansone, Giulia Collatuzzo, Stefano Renzetti, Giorgia Ditano, Carlo Bonfanti, Emma Sala, Luigina Terlenghi, Alberto Matteelli, Mahsa Abedini, Shuffield Seyram Asafo, Paolo Boffetta, Giuseppe De Palma

Summary: Given their occupational risk profile, healthcare workers (HCWs) were prioritized for anti-SARS-CoV-2 vaccination. However, breakthrough infections remained common, especially with new SARS-CoV-2 variants of concern (VOCs) spreading rapidly in Italy. The level of anti-SARS-CoV-2 antibodies does not accurately predict protection from natural infection or vaccination, emphasizing the need for further research on susceptibility to SARS-CoV-2. This study aimed to characterize the risk profiles for SARS-CoV-2 infection in recently booster-dosed HCWs, finding that hybrid immunization (vaccine plus natural infection) elicited higher antibody levels. However, it did not always provide better protection against reinfection, highlighting the importance of the immunization profile as a virus-host interaction modifier. Despite high resistance to reinfection, there was a notable infection rate (5.6%) during the peri-booster period, reinforcing the importance of preventive measures.

VACCINES (2023)

Article Biotechnology & Applied Microbiology

Objective Evaluation of Active Interactions between the Operator and Display Screen Equipment Using an Innovative Acquisition System

Giuseppe De Palma, Emma Sala, Sofia Rubino, Simone Dalola, Marco Ferrari, Daniele Marioli, Pietro Apostoli, Cesare Tomasi, Francesca Righetti, Flavia Mattioli, Vittorio Ferrari

Summary: This study evaluated the performance of an original and innovative system that can objectively assess the interactions between operators and display screen equipment (DSE). The system collects electrical impulses generated by mouse, keyboard, and camera to evaluate active operator-DSE interactions. The obtained results show that the system is effective in collecting activity data and can provide an objective evaluation of active time spent by DSE operators, facilitating more accurate occupational health risk assessment and management.

BIOENGINEERING-BASEL (2023)

Article Biotechnology & Applied Microbiology

A Twenty-Year Retrospective Analysis of Risk Assessment of Biomechanical Overload of the Upper Limbs in Multiple Occupational Settings: Comparison of Different Ergonomic Methods

Emma Sala, Lorenzo Cipriani, Andrea Bisioli, Emilio Paraggio, Cesare Tomasi, Pietro Apostoli, Giuseppe De Palma

Summary: This study retrospectively analyzed the risk assessment of biomechanical overload of the upper limb using multiple assessment methods, including the Washington State Standard, threshold limit values proposed by ACGIH, OCRA checklist, RULA, and INRS's Strain Index and Outil de Reperage et d'Evaluation des Gestes. The results showed differences in the assessment of action frequency and posture among the methods, while strength assessment was more consistent. Therefore, the use of multiple assessment methods ensures a more comprehensive analysis of biomechanical risk.

BIOENGINEERING-BASEL (2023)

Article Public, Environmental & Occupational Health

A method for the risk assessment of biomechanical overload in hospital physiotherapists

Emma Sala, Andrea Bisioli, Pietro Ponzoni, Alessandro De Bellis, Emilio Paraggio, Giuseppe De Palma

Summary: This study proposes a new methodology, named WB-RAMBO, to assess the risk in the activities performed by physiotherapists. By breaking down each type of intervention into elementary operations and integrating multiple ergonomic methods, the method provides a risk assessment for each operation. The results show that the risk assessment is acceptable from an ergonomic perspective, and the work plan can be redesigned and adapted based on the assessment.

MEDICINA DEL LAVORO (2022)

Article Immunology

Determinants of anti-S immune response at 6 months after COVID-19 vaccination in a multicentric European cohort of healthcare workers - ORCHESTRA project

Giulia Collatuzzo, Giovanni Visci, Francesco S. Violante, Stefano Porru, Gianluca Spiteri, Maria Grazia Lourdes Monaco, Francesca Larese Fillon, Corrado Negro, Christian Janke, Noemi Castelletti, Giuseppe De Palma, Emanuele Sansone, Dana Mates, Silvia Teodorescu, Eleonora Fabianova, Jana Beresova, Luigi Vimercati, Silvio Tafuri, Mahsa Abedini, Giorgia Ditano, Shuffield S. Asafo, Paolo Boffetta

Summary: This study analyzed the determinants of anti-SARS-CoV-2 IgG titer at 6 months after 2-dose COVID-19 vaccination in an international cohort of healthcare workers. The results showed that female sex, young age, past infection, two vaccine doses, and mRNA and heterologous vaccination predicted higher antibody levels. These findings provide valuable data for comparison with trends observed with longer follow-ups.

FRONTIERS IN IMMUNOLOGY (2022)

Article Public, Environmental & Occupational Health

Serological response after SARS-CoV2 vaccination in healthcare workers: a multicenter study

Giovanni Visci, Carlotta Zunarelli, Ihab Mansour, Stefano Porru, Giuseppe De Palma, Xavier Duval, Maria Grazia Lourdes Monaco, Gianluca Spiteri, Angela Carta, Giuseppe Lippi, Giuseppe Verlato, Emanuele Sansone, Emma Sala, Massimo Lombardo, Mahsa Abedini, Francesco Violante, Paolo Boffetta

Summary: Characterizing immunological response following COVID-19 vaccination is crucial for public health. This study investigated the proportion, level, and determinants of humoral response in vaccinated healthcare workers. Results showed that almost all vaccinated individuals developed a humoral response, with better antibody levels observed in female, younger, and previously infected individuals.

MEDICINA DEL LAVORO (2022)

Article Environmental Sciences

Comparing nearshore and embayment scale assessments of submarine groundwater discharge: Significance of offshore groundwater discharge as a nutrient pathway

Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto

Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

Impact of NO2 emissions from household heating systems with wall-mounted gas stoves on indoor and ambient air quality in Chinese urban areas

Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li

Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Letter Environmental Sciences

Letter to the editor regarding Collard et al. (2023): Persistence and mobility (defined as organic-carbon partitioning) do not correlate to the detection of substances found in surface and groundwater: Criticism of the regulatory concept of persistent and mobile substances

Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

Harnessing the composition of dissolved organic matter in lagoon sediment in association with rare earth elements using fluorescence and UV-visible absorption spectroscopy

Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu

Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

An advanced global soil erodibility (K) assessment including the effects of saturated hydraulic conductivity

Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell

Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

Comparison of adsorption-extraction (AE) workflows for improved measurements of viral and bacterial nucleic acid in untreated wastewater

Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed

Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

Insights the dominant contribution of biomass burning to methanol-soluble PM2.5 bounded oxidation potential based on multilayer perceptron neural network analysis in Xi'an, China

Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen

Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

A macroplastic vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i

Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro

Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

Anthropic disturbances impact the soil microbial network structure and stability to a greater extent than natural disturbances in an arid ecosystem

Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso

Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

Adsorption of metal ions by oceanic manganese nodule and deep-sea sediment: Behaviour, mechanism and evaluation

Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang

Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

Advanced oxidation process of valsartan by activated peroxymonosulfate: Chemical characterization and ecotoxicological effects of its byproducts

Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli

Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

Photodegradation of typical pharmaceuticals changes toxicity to algae in estuarine water: A metabolomic insight

Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng

Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

Association of ambient air pollution and pregnancy rate among women undergoing assisted reproduction technology in Fujian, China: A retrospective cohort study

Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang

Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

The predictive machine learning model of a hydrated inverse vulcanized copolymer for effective mercury sequestration from wastewater

Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi

Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Article Environmental Sciences

Aluminium bioaccumulation in colon cancer, impinging on epithelial-mesenchymal-transition and cell death

Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca

Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)