Chemical conversion of human and mouse fibroblasts into motor neurons

Direct Generation of Human Neuronal Cells from Adult Astrocytes by Small Molecules

(2017) Longfei Gao et al.   Stem Cell Reports

Chemical conversion of mouse fibroblasts into functional dopaminergic neurons

(2016) Yonghui Wang et al.   EXPERIMENTAL CELL RESEARCH

Integrated transcriptome analysis of human iPS cells derived from a fragile X syndrome patient during neuronal differentiation

(2016) Ping Lu et al.   Science China-Life Sciences

Treatment of multiple sclerosis by transplantation of neural stem cells derived from induced pluripotent stem cells

(2016) Chao Zhang et al.   Science China-Life Sciences

Epigenetic Control of Reprogramming and Transdifferentiation by Histone Modifications

(2016) Hua Qin et al.   Stem Cell Reviews and Reports

Direct Lineage Reprogramming Reveals Disease-Specific Phenotypes of Motor Neurons from Human ALS Patients

(2016) Meng-Lu Liu et al.   Cell Reports

Epigenetic Control of Reprogramming and Transdifferentiation by Histone Modifications

(2016) Hua Qin et al.   Stem Cell Reviews and Reports

Small molecules increase direct neural conversion of human fibroblasts

(2016) Ulrich Pfisterer et al.   Scientific Reports

Direct conversion of mouse fibroblasts to GABAergic neurons with combined medium without the introduction of transcription factors or miRNAs

(2015) Huiming Xu et al.   CELL CYCLE

Direct conversion of astrocytes into neuronal cells by drug cocktail

(2015) Lin Cheng et al.   CELL RESEARCH

Direct Lineage Reprogramming: Strategies, Mechanisms, and Applications

(2015) Jun Xu et al.   Cell Stem Cell

Direct Conversion of Normal and Alzheimer’s Disease Human Fibroblasts into Neuronal Cells by Small Molecules

(2015) Wenxiang Hu et al.   Cell Stem Cell

Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons

(2015) Lei Zhang et al.   Cell Stem Cell

Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons

(2015) Xiang Li et al.   Cell Stem Cell

Highly efficient direct conversion of human fibroblasts to neuronal cells by chemical compounds

(2015) Ping Dai et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Notch Signaling Regulates Motor Neuron Differentiation of Human Embryonic Stem Cells

(2015) Etti Ben-Shushan et al.   STEM CELLS

Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells

(2015) Katrina L. Adams et al.   Nature Communications

Generation of neural progenitor cells by chemical cocktails and hypoxia

(2014) Lin Cheng et al.   CELL RESEARCH

High-efficiency motor neuron differentiation from human pluripotent stem cells and the function of Islet-1

(2014) Qiuhao Qu et al.   Nature Communications

A Small Molecule Screen in Stem-Cell-Derived Motor Neurons Identifies a Kinase Inhibitor as a Candidate Therapeutic for ALS

(2013) Yin M. Yang et al.   Cell Stem Cell

Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells

(2013) M. W. Amoroso et al.   JOURNAL OF NEUROSCIENCE

Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons

(2013) Meng-Lu Liu et al.   Nature Communications

Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

(2012) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Small molecules enable highly efficient neuronal conversion of human fibroblasts

(2012) Julia Ladewig et al.   NATURE METHODS

Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons

(2011) Esther Y. Son et al.   Cell Stem Cell

Rapid and Efficient Generation of Functional Motor Neurons From Human Pluripotent Stem Cells Using Gene Delivered Transcription Factor Codes

(2011) Mark E Hester et al.   MOLECULAR THERAPY

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

(2011) W. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem cell therapies for spinal cord injury

(2010) Vibhu Sahni et al.   Nature Reviews Neurology

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

GSK-3 is a master regulator of neural progenitor homeostasis

(2009) Woo-Yang Kim et al.   NATURE NEUROSCIENCE

Differentiation of spinal motor neurons from pluripotent human stem cells

(2009) Bao-Yang Hu et al.   Nature Protocols

Spinal muscular atrophy

(2008) Mitchell R Lunn et al.   LANCET

Directed Differentiation of Ventral Spinal Progenitors and Motor Neurons from Human Embryonic Stem Cells by Small Molecules

(2008) Xue-Jun Li et al.   STEM CELLS