Phenotype prediction of nonsynonymous single nucleotide polymorphisms in human phase II drug/xenobiotic metabolizing enzymes: perspectives on molecular evolution

Prediction of Deleterious Non-synonymous Single-Nucleotide Polymorphisms of Human Uridine Diphosphate Glucuronosyltransferase Genes

(2009) Yuan Ming Di et al.   AAPS Journal

A Bioinformatics Approach for the Phenotype Prediction of Nonsynonymous Single Nucleotide Polymorphisms in Human Cytochromes P450

(2009) L.-L. Wang et al.   DRUG METABOLISM AND DISPOSITION

N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine

(2009) David W Hein   Expert Opinion on Drug Metabolism & Toxicology

Molecular phylogeny, long-term evolution, and functional divergence of flavin-containing monooxygenases

(2009) Da Cheng Hao et al.   GENETICA

Positional conservation and amino acids shape the correct diagnosis and population frequencies of benign and damaging personal amino acid mutations

(2009) S. Kumar et al.   GENOME RESEARCH

Molecular evolution and positive Darwinian selection of the chloroplast maturase matK

(2009) Da Cheng Hao et al.   JOURNAL OF PLANT RESEARCH

Clinical Pharmacogenetics and Potential Application in Personalized Medicine

(2008) Shu-Feng Zhou et al.   CURRENT DRUG METABOLISM

Structure/Function Evaluations of Single Nucleotide Polymorphisms in Human N-Acetyltransferase 2

(2008) Jason Walraven et al.   CURRENT DRUG METABOLISM

Molecular evolution of paclitaxel biosynthetic genes TS and DBAT of Taxus species

(2008) Da Cheng Hao et al.   GENETICA

The proportion of mutations predicted to have a deleterious effect differs between gain and loss of function genes in neurodegenerative disease

(2008) Paul N. Valdmanis et al.   HUMAN MUTATION

Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2)

(2008) A. M. O’Halloran et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

COMTpolymorphisms affecting protein expression are risk factors for endometrial cancer

(2008) Hiroshi Hirata et al.   MOLECULAR CARCINOGENESIS

Proportionally more deleterious genetic variation in European than in African populations

(2008) Kirk E. Lohmueller et al.   NATURE

Molecular population genetics of PCSK9: a signature of recent positive selection

(2008) Keyue Ding et al.   Pharmacogenetics and Genomics

Functional characterization of 23 allelic variants of thiopurine S-methyltransferase gene (TPMT*2 – *24)

(2008) Shuta Ujiie et al.   Pharmacogenetics and Genomics

Changes in consensus arylamine N-acetyltransferase gene nomenclature

(2008) David W. Hein et al.   Pharmacogenetics and Genomics

Glutathione S-transferase GSTT1 and GSTM1 allozymes: beyond null alleles

(2008) José AG Agúndez et al.   PHARMACOGENOMICS

Prediction by Graph Theoretic Measures of Structural Effects in Proteins Arising from Non-Synonymous Single Nucleotide Polymorphisms

(2008) Tammy M. K. Cheng et al.   PLoS Computational Biology

Assessing the Evolutionary Impact of Amino Acid Mutations in the Human Genome

(2008) Adam R. Boyko et al.   PLoS Genetics