Article
Materials Science, Multidisciplinary
Patricia Risch, Christian Adlhart
Summary: This study presents the preparation of ultralight chitosan-glutaraldehyde nanofiber sponges for filtration applications. The sponges showed excellent particle adsorption capabilities and significant reduction in turbidity of particle suspensions. This biocompatible filter has potential applications in addressing environmental challenges such as microplastics.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Chemistry, Applied
Bikendra Maharjan, Jeesoo Park, Vignesh Krishnamoorthi Kaliannagounder, Ganesh Prasad Awasthi, Mahesh Kumar Joshi, Chan Hee Park, Cheol Sang Kim
Summary: This study addressed the insufficient mechanical strength of natural hydrogel scaffolds in bone tissue engineering by incorporating regenerated cellulose nanofibers into chitosan hydrogel. The resulting rCL/CS composite scaffold showed improved compressive strength, biomineralization, and pre-osteoblast cell viability. The enhanced osteogenic differentiation ability of rCL/CS composite scaffold suggests its promise as a three-dimensional bio-scaffold for bone tissue engineering.
CARBOHYDRATE POLYMERS
(2021)
Article
Materials Science, Multidisciplinary
Hoan Ngoc Doan, Phu Phong Vo, Andrea Baggio, Masaki Negoro, Kenji Kinashi, Yasuro Fuse, Wataru Sakai, Naoto Tsutsumi
Summary: This study demonstrated a facile and sustainable method to prepare a flexible electrospun nanofiber/nanonet membrane using biodegradable polymers for controllable oil/water separation, showing excellent separation efficiencies for various oil/water mixtures.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Engineering, Environmental
Md Eman Talukder, Md Nahid Pervez, Wang Jianming, Ziwei Gao, George K. Stylios, Mohammad Mahbubul Hassan, Hongchen Song, Vincenzo Naddeo
Summary: The chitosan-modified-poly(vinyl alcohol)/sodium alginate nanofiber membrane showed high adsorption capacity for As(III) removal from aqueous solutions. The adsorption process was affected by initial pH and the presence of competing anions, while the nanofiber membrane could be easily regenerated and maintained high removal rates after multiple cycles.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Materials Science, Multidisciplinary
Zhenzhen Huang, Yanxin Wang, Xianhang Yan, Xinhui Mao, Zhiyuan Gao, Matt J. Kipper, Linjun Huang, Jianguo Tang
Summary: In this study, a luminescent lanthanide complex, Eu(tta)3phen, was used to prepare fluorescent nanofiber films. The nanofibers, composed of chitosan and polyethylene oxide containing silica nanoparticles, encapsulated the Eu(tta)3phen. The resulting Na-CS/PEO-SiO2@Eu(tta)3phen fiber film showed high sensitivity and a wide detection range, making it a recyclable sensor for the detection of Cu2+ ions.
Article
Materials Science, Textiles
Eiichi Shoji, Yusuke Hikida, Masanori Hatashita
Summary: This study proposes a fabrication method to obtain composites of PVA/ionic cellulose nanofibers by manipulating fiber structures through electrospinning. It successfully reconstructs nanofibers with less-fused structures, containing both ionic cellulose nanofibers and PVA, revealing the potential for fabricating nonwoven fabrics of polyelectrolyte nanofibers.
JOURNAL OF NATURAL FIBERS
(2022)
Article
Engineering, Multidisciplinary
Seyede Mahtab Hosseini, Majid Abdouss, Saeedeh Mazinani, Azim Soltanabadi, Mohammadreza Kalaee
Summary: This study prepared polyvinyl alcohol (PVA) nanofibers containing chitosan nanoparticles and drug-loaded graphene oxide-magnetite nanocomposites for smart wound dressing. The nanofiber membranes showed high water absorption, low degradability, controlled drug release, good antimicrobial properties against gram-positive and gram-negative bacteria, and high compatibility with cells.
COMPOSITES PART B-ENGINEERING
(2022)
Article
Polymer Science
Zsuzsanna Czibulya, Attila Csik, Ferenc Toth, Petra Pal, Istvan Csarnovics, Romana Zelko, Csaba Hegedus
Summary: This study focused on preparing scaffolds with optimized hydrophilicity for oral applications through adjusting the ratios of polyvinyl alcohol (PVA)/chitosan/citric acid. The enhanced hydrophobicity and biocompatibility of the scaffolds were supported by contact angle measurements, IR spectroscopy results, and Alamar Blue assay. Various analytical techniques were used to confirm the performance of the scaffolds, demonstrating their feasibility for intraoral cavity applications.
Article
Chemistry, Applied
Weiyang Shen, Yongxin Wang, Yali Li, Zongyao Cui, Yitong Yang, Honglu Shi, Chenfeng Xu, Tingjie Yin
Summary: In this study, a mild acid-responsive nanofiber membrane was fabricated, loaded with ciprofloxacin to prevent bacterial infection and promote wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Multidisciplinary
Hongyu Lv, Meng Zhao, Yiran Li, Kun Li, Shaojuan Chen, Wenwen Zhao, Shaohua Wu, Yantao Han
Summary: This study developed a novel nanofibrous dressing for the treatment of hard-to-heal diabetic wounds. The dressing exhibited multiple biological functions, including anti-inflammation, antioxidation, pro-angiogenesis, and hemostasis.
Article
Biochemistry & Molecular Biology
Maryam Zarei, Abdolreza Samimi, Mohammad Khorram, Mahnaz M. Abdi, Seyyed Iman Golestaneh
Summary: The conductive electrospun nanofiber scaffold containing polypyrrole was fabricated to accelerate tissue healing, with polypyrrole dispersed perfectly in the fibers and enhancing their conductivity up to 164.274 x 10(-3) s/m. The nanofibers with 10% polypyrrole showed better cell adhesion, growth, and proliferation properties, making them suitable for various tissue applications and particularly appropriate for body parts with electrical signals such as cardiovascular, heart muscles, or nerves.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Materials Science, Textiles
Hongyan Wu, Shuang Yan, Yang Wang, Changhuan Zhang
Summary: Chitosan/Polybutylenes succinate nanofiber membrane was prepared by electrospinning to fully utilize the advantages of Chitosan in wound repair. The content of Chitosan was found to affect the properties of the composite fiber membrane, with the best performance observed at 90% Chitosan content, making it suitable for wound hemostatic dressing.
JOURNAL OF INDUSTRIAL TEXTILES
(2022)
Article
Chemistry, Multidisciplinary
Eunjoo Moon, Eungsu Kang, Wooho Song, Bum Jin Kim, Hyung Joon Cha, Yoo Seong Choi
Summary: Chitosan-based nanofibers are promising biomaterials for wound healing and dressing applications due to their biocompatibility, biodegradability, and antibacterial properties. However, their unstable spinnability has limited their further use. In this study, oleamide, a fatty acid amide, was added to chitosan to improve the spinnability of the nanofibers. The addition of oleamide resulted in lower viscosity of the electrospinning solution, leading to enhanced spinnability. The chitosan/oleamide nanofibers exhibited higher hydrophobicity and decreased tensile strength compared to chitosan-only nanofibers. Cell adhesion in vitro was similar or slightly higher on the blended nanofibers, but cell proliferation was decreased, likely due to the increased hydrophobicity. These findings suggest that chitosan/oleamide nanofibers with improved spinnability could be used for wound dressing with antibacterial properties and moderate hydrophobicity.
KOREAN JOURNAL OF CHEMICAL ENGINEERING
(2023)
Article
Engineering, Environmental
Atefeh Mousavi Anjeh, Seyed Reza Nabavi
Summary: In this study, CS/PA6 composite nanofibers were prepared by electrospinning and the addition of GO improved the performance of the composite nanofibers. The results showed that the addition of GO led to the formation of a spider-web-like structure and improved the Young's modulus and thermal degradation resistance of the nanofibers. Furthermore, the prepared composite nanofibers exhibited good adsorption capacity for lead ions.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2022)
Article
Polymer Science
Hossein Hosseini, M. Khodabandeh Shahraky, Amir Amani, Farzaneh S. Landi
Summary: Nanofibers prepared via electrospinning method are a new treatment method for difficult-to-heal wounds, providing hydrophilic and non-toxic characteristics with sustained release of therapeutic proteins.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2021)
Article
Materials Science, Biomaterials
Chiaki Yoshikawa, Tadashi Nakaji-Hirabayashi, Nanami Nishijima, Punnida Nonsuwan, Rou Jun Toh, Wioleta Kowalczyk, Helmut Thissen
Summary: The study demonstrated a novel approach for selectively binding specific cells by incorporating peptide monomers into ultra-low fouling coatings. This method shows potential applications in surface cell binding selectivity and maintains excellent anti-biofouling properties.
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Chiaki Yoshikawa, Keita Sakakibara, Punnida Nonsuwan, Tomohiko Yamazaki, Yoshinobu Tsujii
Summary: A simple and versatile method for fabricating nonbiofouling coatings using well-defined bottlebrushes instead of CPBs is reported in this study. The CPB-type bottlebrush films showed significantly better nonbiofouling characteristics than those of the SDPB-type bottlebrush films.
Article
Biochemistry & Molecular Biology
Xida Yuan, Punnida Nonsuwan, Miwako Shobo, Robin Rajan, Tomohiko Yamazaki, Keita Sakakibara, Kazuaki Matsumura, Chiaki Yoshikawa
Summary: This study investigates the unique mechanism of cellular flocculation based on colloidal flocculation grafted CNF (CNF-PSSNa), using concentrated polymer brush-modified cellulose nanofibers (CNFs) with different fiber lengths. The results show that the size and survival rate of the cell clusters formed through cellular flocculation can be controlled by modifying the CNF-PSSNa fiber lengths.
Article
Chemistry, Multidisciplinary
Irem Nur Gamze Ozbilgin, Tomohiko Yamazaki, Junpei Watanabe, Hong-Tao Sun, Nobutaka Hanagata, Naoto Shirahata
Summary: We report carboxy-terminated silicon quantum dots (SiQDs) that are highly soluble in water due to the high coverage of surface monolayers, exhibit bright light emission with high photoluminescence quantum yields (PLQYs), show long-term stability in PL property for cell monitoring, have low toxicity to cells, and display a high photothermal response.
Article
Materials Science, Biomaterials
Punnida Nonsuwan, Nanami Nishijima, Keita Sakakibara, Tadashi Nakaji-Hirabayashi, Chiaki Yoshikawa
Summary: Concentrated poly(styrene sulfonate sodium salt) brush-modified cellulose nanofibers were used as building blocks to develop new three-dimensional (3D) cell culture systems for articular cartilage regeneration, by controlling the self-assembly of human mesenchymal stem cells (hMSCs). Unique 3D cellular structures, such as giant spheres and sheets, were successfully formed.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Green & Sustainable Science & Technology
B. K. Nahak, S. Preetam, Deepa Sharma, S. K. Shukla, Mikael Syvajarvi, Dana-Cristina Toncu, Ashutosh Tiwari
Summary: This review article discusses the use of lignocellulosic biomass as a sustainable source of energy in solid, liquid, and gas forms. The effects of physical, chemical, and biological treatments on biomass and the properties of derived energy generations are compared to commercially used fuels.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS
(2022)
Article
Nanoscience & Nanotechnology
Chiaki Yoshikawa, Ryoma Takagi, Tadashi Nakaji-Hirabayashi, Toshiro Ochi, Yasushi Kawamura, Helmut Thissen
Summary: The novel marine antifouling coating technology combines bottlebrush polymers and photoreactive copolymers to achieve effective antifouling properties in one step. It has demonstrated stability against acid and base hydrolysis and prevented marine organism attachment for up to 73 days in sea water.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Chiaki Yoshikawa, Keita Sakakibara, Punnida Nonsuwan, Miwako Shobo, Xida Yuan, Kazuaki Matsumura
Summary: This study investigated the impact of the surface charge of concentrated polymer brush (CPB)-grafted cellulose nanofibers (CNFs) on HepG2 cell flocculation. The results showed that the surface charge affected the floc size, with anionic CNF forming larger flocs compared to cationic ones, and lower zeta-potential leading to smaller floc sizes. Appropriate electrostatic interactions are crucial for floc formation and improved cell function in three-dimensional (3D) cell culture systems.
Article
Biochemistry & Molecular Biology
Dandan Zhao, Anh Thi Tram Tu, Miwako Shobo, Nguyen Bui Thao Le, Chiaki Yoshikawa, Kazuhisa Sugai, Yoji Hakamata, Tomohiko Yamazaki
Summary: In this study, the ε-PLL/G4-CpG ODN complex was successfully synthesized as a carrier, providing better stability against nucleases and significantly improved cellular uptake. Modulation of the N/P ratio successfully tuned the levels of immune cytokine production.
Article
Thermodynamics
R. Roshan, B. K. Nahak, D. Mahata, P. Yadav, S. Panda, Santanu Patra, S. S. Mahato, Ashutosh Tiwari, S. Mahata
Summary: In this study, surface functionalized cadmium sulfide nanoparticles were used as a photocatalyst for efficient demineralization of methylene violet and rhodamine B to produce hydrogen. The influence of sulfur vacancy on photocatalytic hydrogen production was systematically investigated, and it was found that sulfur vacancies on the surface of cadmium sulfide quantum dots could improve charge separation and catalytic performance.
ENERGY CONVERSION AND MANAGEMENT
(2023)
Article
Biochemistry & Molecular Biology
Anchu Viswan, Chiaki Yoshikawa, Ayana Yamagishi, Yuichi Furuhata, Yoshio Kato, Tomohiko Yamazaki, Chikashi Nakamura
Summary: Direct delivery of genome-editing proteins into plant tissues can produce DNA-free genome-edited crops, eliminating the need for backcrossing to remove vector-derived DNA. This study modified a microneedle array with a bioactive polymer, resulting in improved protein delivery and potential implications for the development of more effective plant genome editing techniques.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Nguyen Bui Thao Le, Anh Thi Tram Tu, Dandan Zhao, Chiaki Yoshikawa, Kohsaku Kawakami, Yoshihisa Kaizuka, Tomohiko Yamazaki
Summary: This study investigated the effect of charge ratios on the characteristics and cytokine production of cationic liposome complexes. The results showed that complexes with low charge ratios induced higher levels of IL-6 and IFN-alpha simultaneously. Furthermore, there was a positive correlation between cellular uptake of the complex and cytokine induction.
Review
Nanoscience & Nanotechnology
Bishal Kumar Nahak, Anshuman Mishra, Subham Preetam, Ashutosh Tiwari
Summary: The organ-on-a-chip (OoC) technology provides an accurate pathway for biomedical applications from preclinical to clinical translational precision. It accurately represents human physiology in vitro and allows noninvasive real-time monitoring and treatment. The technology combines emerging approaches such as advanced materials, artificial intelligence, machine learning, three-dimensional bioprinting, and genomics, and has broad application prospects.
ACS APPLIED BIO MATERIALS
(2022)
Review
Nanoscience & Nanotechnology
Sudheesh K. Shukla, Santanu Patra, Trupti R. Das, Dharmesh Kumar, Anshuman Mishra, Ashutosh Tiwari
Summary: The rapid spread of COVID-19 has posed a major threat to public health globally. The lack of effective medication and widely accepted immunization is a challenge, and there is a need for rapid and accurate diagnostic approaches. Current research suggests that the use of candidate biomarkers and sensor technology can provide effective diagnosis services.
Review
Materials Science, Multidisciplinary
Varshika Singh, Santanu Patra, Natarajan Arul Murugan, Dana-Cristina Toncu, Ashutosh Tiwari
Summary: The paradigm of advanced materials has experienced exponential growth, encompassing new dimensions such as digital design, dynamics, and functions. Research in materials modeling and computational techniques have provided valuable predictions for designing novel materials with improved properties, leading to significant advancements in new-age devices.
MATERIALS ADVANCES
(2022)