Journal
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS
Volume 11, Issue 3, Pages -Publisher
NATL INST MATERIALS SCIENCE
DOI: 10.1088/1468-6996/11/3/035001
Keywords
type I collagen; hybrids; DSC measurement
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Novel type I collagen hybrid fibrils were fabricated by neutralizing a mixture of type I fish scale collagen solution and type I porcine collagen solution with a phosphate buffer saline at 28 degrees C. Their structure was discussed in terms of the volume ratio of fish/porcine collagen solution. Scanning electron and atomic force micrographs showed that the diameter of collagen fibrils derived from the collagen mixture was larger than those derived from each collagen, and all resultant fibrils exhibited a typical D-periodic unit of similar to 67 nm, irrespective of volume ratio of both collagens. Differential scanning calorimetry revealed only one endothermic peak for the fibrils derived from collagen mixture or from each collagen solution, indicating that the resultant collagen fibrils were hybrids of type I fish scale collagen and type I porcine collagen.
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