Article
Optics
Kangjian Hua, Bo Liu, Zhen Chen, Liang Fang, Huachuang Wang
Summary: This paper introduces a method called First Signal Photon Unit (FSPU) for rapidly reconstructing depth images in low signal photon level with strong noise robustness. Compared to traditional photon-counting methods and state-of-the-art unmixing methods, the FSPU method demonstrates superior performance in both simulations and experiments.
Article
Optics
Zhupeng Li, Xintong Liu, Jianyu Wang, Zuoqiang Shi, Lingyun Qiu, Xing Fu
Summary: This paper proposes a novel detection methodology for NLOS imaging based on time-sequential first photon data. Experimental and synthetic data verification shows a significant reduction in acquisition time cost compared to traditional methods, which could contribute to real-time and photon-starved NLOS imaging for practical applications.
Article
Optics
Fabian Wagner, Florian Schiffers, Florian Willomitzer, Oliver Cossairt, Andreas Velten
Summary: The development of single-photon counting detectors and arrays has significantly progressed in recent years, particularly in applications such as LIDAR devices. This work presents a 3D imaging device based on real thermal light intensity interferometry, utilizing gated SPAD technology to image a basic 3D scene efficiently. The synchronized photon counting approach proposed in this study allows for the use of more light modes to enhance 3D ranging performance, with advantages including robustness to atmospheric scattering and autonomy through external light sources, making it a promising option for future applications.
Editorial Material
Biochemical Research Methods
Jerome A. Lecoq, Roman Boehringer, Benjamin F. Grewe
Summary: New three-photon miniature microscopes enable the study of neuronal networks in the deep regions of the brains of behaving animals.
Article
Engineering, Electrical & Electronic
Yiwei Chen, Chen Jiang, Yong Liu, Hongye Su, Xiaomin Hu, Yu Pan
Summary: This study presents an upconversion-based single-photon imager for full-range and accurate 3-D imaging. Compared to previous imagers, the proposed system achieves significantly higher imaging speed and improved efficiency. The application of a high-repetition laser and a nanosecond optical delay line enables full-range imaging against high solar background noise.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2023)
Article
Multidisciplinary Sciences
Giovanni Barbera, Rachel Jun, Yan Zhang, Bo Liang, Yun Li, Da-Ting Lin
Summary: In this work, a lightweight one-photon microscope capable of imaging at different focal depths is presented. The focal plane can be dynamically changed by modulating the pulse width of the control signal, enabling the switching of focal plane between frames. Experimental results showed an increase in the number of imaged neurons compared to single plane imaging.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Multidisciplinary
Brandon J. Furey, Benjamin J. Stacy, Tushti Shah, Rodrigo M. Barba-Barba, Ramon Carriles, Alan Bernal, Bernardo S. Mendoza, Brian A. Korgel, Michael C. Downer
Summary: Colloidal nanocrystalline silicon quantum dots (nc-SiQDs) excited by two-photon in the near-infrared (NIR) range have potential applications in deep biological imaging. The two-photon absorption (2PA) cross section of colloidal nc-SiQDs is measured, and it is found to be smaller for smaller diameter nanocrystals. The efficiencies of nc-SiQDs for bioimaging using two-photon excited photoluminescence (2PE-PL) are compared to other quantum dots and molecular fluorophores and found to be comparable or superior at greater depths.
Article
Astronomy & Astrophysics
M. Bashkanov, D. P. Watts, S. Kay, S. Abt, P. Achenbach, P. Adlarson, F. Afzal, Z. Ahmed, C. S. Akondi, J. R. M. Annand, H. J. Arends, R. Beck, M. Biroth, N. Borisov, A. Braghieri, W. J. Briscoe, F. Cividini, C. Collicott, S. Costanza, A. Denig, E. J. Downie, P. Drexler, S. Fegan, A. Fix, S. Gardner, D. Ghosal, D. I. Glazier, I. Gorodnov, W. Gradl, M. Gunther, D. Gurevich, L. Heijkenskjoeld, D. Hornidge, G. M. Huber, A. Kaser, V. L. Kashevarov, M. Korolija, B. Krusche, A. Lazarev, K. Livingston, S. Lutterer, I. J. D. MacGregor, D. M. Manley, P. P. Martel, R. Miskimen, E. Mornacchi, C. Mullen, A. Neganov, A. Neiser, M. Ostrick, P. B. Otte, D. Paudyal, P. Pedroni, A. Powell, S. N. Prakhov, V. Sokhoyan, K. Spieker, O. Steffen, I. I. Strakovsky, T. Strub, I. Supek, A. Thiel, M. Thiel, A. Thomas, Yu. A. Usov, S. Wagner, J. Wettig, M. Wolfes, N. Zachariou
Summary: A first measurement of polarisation transfer from a circularly-polarised photon to the final state neutron in deuterium photodisintegration was conducted. The measurement was done over the photon energy range of 370-700 MeV and for neutron breakup angles of 45-120 degrees. The polarisation of the final state neutrons was determined using a nucleon polarimeter, and the data was compared to a theoretical model and existing measurements.
Article
Biochemical Research Methods
Bowen Wei, Chenmao Wang, Zongyue Cheng, Baoling Lai, Wen-Biao Gan, Meng Cui
Summary: COMPACT allows imaging of large volumes in the brain through a periscope-like probe inside a glass capillary, enabling observation of the dynamics of neuronal structure and function in different regions. This technology provides a valuable tool for understanding the neural circuit mechanisms underlying behavior.
Article
Optics
Yuriy Shymkiv, Rafael Yuste
Summary: A technical challenge in neuroscience is to record and manipulate the activity of neurons in living animals. In this study, an integrated optical design using a single spatial light modulator (SLM) for simultaneous imaging and photostimulation is presented. Axially dependent adaptive optics and software for calibrations and closed-loop neuroscience experiments were also developed. The system's performance was demonstrated with simultaneous calcium imaging and optogenetics in vivo in the mouse primary auditory cortex.
Review
Chemistry, Analytical
Vinayak Juvekar, Hyo Won Lee, Dong Joon Lee, Hwan Myung Kim
Summary: Two-photon microscopy is an important tool for deep-tissue imaging, providing high-resolution fluorescence images beyond millimeter depths. Recent research has focused on developing innovative strategies and probes for quantitative analysis using two-photon fluorescence.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Optics
Zhan-Ming Li, Heng Zhou, Zhong-Yuan Li, Zeng-Quan Yan, Cheng-Qiu Hu, Jun Gao, Shi-Bao Wu, Si-Yuan Yin, Xian-Min Jin
Summary: This study demonstrates a thresholded single-photon imaging and detection scheme to extract photon signals from noisy underwater environments, achieving underwater detection down to 0.8 photons per pulse in high-loss underwater conditions. Results break the limits of classical underwater imaging and detection and open up possibilities for quantum-enhanced applications in deep-sea exploration.
Article
Biochemical Research Methods
Najva Akbari, Mihailo R. Rebec, Fei Xia, Chris Xu
Summary: Multiphoton fluorescence microscopy uses long excitation wavelengths and nonlinear excitation to increase penetration depth and suppress out-of-focus fluorescence for deep in vivo imaging. However, the imaging depth is limited by tissue scattering and absorption. Three-photon fluorescence microscopy has been developed to overcome this limitation and achieve unprecedented deep in vivo imaging. Further technological development is needed to fully exploit the potential of three-photon microscopy.
BIOMEDICAL OPTICS EXPRESS
(2022)
Review
Chemistry, Multidisciplinary
Luling Wu, Jihong Liu, Ping Li, Bo Tang, Tony D. James
Summary: This tutorial review explores recent advances in the design, construction, and application of two-photon excited fluorescence (TPEF)-based small-molecule probes, discussing advantages, two-photon fluorophores, design strategies, and various applications including photodynamic therapy.
CHEMICAL SOCIETY REVIEWS
(2021)
Article
Nanoscience & Nanotechnology
Feifei Wang, Fuqiang Ren, Zhuoran Ma, Liangqiong Qu, Ronan Gourgues, Chun Xu, Ani Baghdasaryan, Jiachen Li, Iman Esmaeil Zadeh, Johannes W. N. Los, Andreas Fognini, Jessie Qin-Dregely, Hongjie Dai
Summary: By studying light scattering and utilizing new materials technology, the imaging depth of high-resolution optical microscopy in live mammals can be improved. This study demonstrates single-photon excitation fluorescence imaging in the NIR-IIc range, achieving the longest single-photon excitation and emission wavelengths to date for in vivo imaging of mice.
NATURE NANOTECHNOLOGY
(2022)
Article
Multidisciplinary Sciences
Charles Saunders, John Murray-Bruce, Vivek K. Goyal
Article
Engineering, Electrical & Electronic
Joshua Rapp, Yanting Ma, Robin M. A. Dawson, Vivek K. Goyal
IEEE TRANSACTIONS ON SIGNAL PROCESSING
(2019)
Article
Engineering, Electrical & Electronic
Joshua Rapp, Robin M. A. Dawson, Vivek K. Goyal
IEEE TRANSACTIONS ON SIGNAL PROCESSING
(2019)
Article
Engineering, Electrical & Electronic
Daewon Seo, Ravi Kiran Raman, Joong Bum Rhim, Vivek K. Goyal, Lav R. Varshney
IEEE TRANSACTIONS ON SIGNAL PROCESSING
(2019)
Article
Engineering, Electrical & Electronic
Safa C. Medin, John Murray-Bruce, David Castanon, Vivek K. Goyal
IEEE TRANSACTIONS ON COMPUTATIONAL IMAGING
(2019)
Article
Engineering, Electrical & Electronic
Joshua Rapp, Julian Tachella, Yoann Altmann, Stephen McLaughlin, Vivek K. Goyal
IEEE SIGNAL PROCESSING MAGAZINE
(2020)
Article
Multidisciplinary Sciences
Joshua Rapp, Charles Saunders, Julian Tachella, John Murray-Bruce, Yoann Altmann, Jean-Yves Tourneret, Stephen McLaughlin, Robin M. A. Dawson, Franco N. C. Wong, Vivek K. Goyal
NATURE COMMUNICATIONS
(2020)
Article
Optics
Joshua Rapp, Yanting Ma, Robin M. A. Dawson, Vivek K. Goyal
Summary: This study demonstrates a method for measurements at higher incident flux without attenuation by accurately modeling the sequence of detection times as a Markov chain. The proposed algorithm corrects for the distortion in detection histograms caused by dead times, improving depth imaging performance significantly. This approach could potentially enable high-flux acquisitions in other fields such as fluorescence lifetime microscopy or quantum optics applications.
Article
Multidisciplinary Sciences
Cheng Wu, Jianjiang Liu, Xin Huang, Zheng-Ping Li, Chao Yu, Jun-Tian Ye, Jun Zhang, Qiang Zhang, Xiankang Dou, Vivek K. Goyal, Feihu Xu, Jian-Wei Pan
Summary: NLOS imaging reconstructs hidden objects from indirect light paths, achieving breakthroughs in long-range imaging. Hardware and software innovations have successfully increased the standoff distance of NLOS imaging, opening up new possibilities for related applications.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Optics
Shuhui Li, Charles Saunders, Daniel J. Lum, John Murray-Bruce, Vivek K. Goyal, Tomas Cizmar, David B. Phillips
Summary: This paper discusses how compressive sensing can reduce the measurement requirements of optical transmission matrices (TMs), allowing for accurate estimation from fewer measurements, and demonstrates this concept on a multimode fiber. The compressive TM sampling strategy is general and applicable to various scattering samples.
LIGHT-SCIENCE & APPLICATIONS
(2021)
Article
Engineering, Electrical & Electronic
Sheila W. Seidel, Luisa Watkins, Minxu Peng, Akshay Agarwal, Christopher Yu, Vivek K. Goyal
Summary: This work presents a method for online estimation of beam current in particle beam microscopy using the same secondary electron count data. The method relies on time-resolved measurement concept and joint estimators to improve micrograph accuracy. The proposed estimators outperform existing methods and allow for explicit beam current estimation that greatly enhances the quality of micrographs.
IEEE TRANSACTIONS ON COMPUTATIONAL IMAGING
(2022)
Article
Engineering, Electrical & Electronic
Minxu Peng, John Murray-Bruce, Vivek K. Goyal
Summary: This paper establishes a rigorous framework for understanding the potential of using time-resolved measurements in FIB microscopy. By joint processing multiple time-resolved measurements, the impact of source shot noise can be mitigated, leading to substantial improvements in image formation over conventional FIB microscopy. Simulated results are consistent with theoretical analyses, demonstrating the effectiveness of time-resolved measurements.
IEEE TRANSACTIONS ON COMPUTATIONAL IMAGING
(2021)
Article
Engineering, Electrical & Electronic
Sheila W. Seidel, John Murray-Bruce, Yanting Ma, Christopher Yu, William T. Freeman, Vivek K. Goyal
Summary: Passive non-line-of-sight imaging methods are faster and stealthier than active counterparts, leveraging the motion of an occluder or hidden scene. These methods require less complex equipment, with the edge of a wall serving as an aperture to image the hidden region. Light from around the corner is cast onto the floor forming a fan-like penumbra containing information about the hidden scene.
IEEE TRANSACTIONS ON COMPUTATIONAL IMAGING
(2021)
Article
Optics
Joshua Rapp, Robin M. A. Dawson, Vivek K. Goyal
Proceedings Paper
Acoustics
Joong Bum Rhim, Vivek K. Goyal
2018 IEEE INTERNATIONAL CONFERENCE ON ACOUSTICS, SPEECH AND SIGNAL PROCESSING (ICASSP)
(2018)
