Editorial Material
Multidisciplinary Sciences
Virginia Gewin
Summary: Online communities formed last year have stimulated collaborations and discussions about diversity and equity in academic research.
Editorial Material
Multidisciplinary Sciences
Orsolya Barabas, Phoebe A. A. Rice
Summary: CRISPR-Cas is a bacterial defense system that can either protect host cells by attacking invading DNA or assist in the safe insertion of DNA into the genome. The structures of this specific type of CRISPR-Cas system have been successfully visualized.
Editorial Material
Multidisciplinary Sciences
Felicia Kuperwaser, Itai Yanai
Summary: A comprehensive cell atlas of gene expression and regulation in human embryos has provided a unique opportunity for innovative investigation of development through multi-organ and multi-modal analysis.
Editorial Material
Multidisciplinary Sciences
Fahad Rashid, James Berger
Summary: High-resolution structures of bacterial Rho protein in complex with an RNA polymerase enzyme and partner proteins confirm the long-held model of Rho's role in gene transcription termination.
Editorial Material
Multidisciplinary Sciences
Pavel V. Baranov, John F. Atkins
Summary: Messenger RNA has 64 possible codons, three of which usually stop protein synthesis. However, certain organisms can utilize all codons to determine amino acids, partially due to an unexpected characteristic of transfer RNA.
Editorial Material
Multidisciplinary Sciences
Leonid A. Mirny
Summary: The study reveals that loop extrusion, essential for chromosome folding and function, also plays a crucial part in repairing double-strand DNA breaks.
Editorial Material
Multidisciplinary Sciences
Alison Abbott
Summary: Researchers are interested in understanding the reasons behind cell secretion of vesicles and the functions of these vesicles during delivery.
Editorial Material
Multidisciplinary Sciences
Ronald Cutler, Jan Vijg
Summary: The study has shown that radiation-damaged paternal DNA causes embryos of the second generation of nematode worms, but not the first, to die. The proposed mechanisms explain why this effect is not observed in humans.
Article
Biochemistry & Molecular Biology
Tzahi Gabzi, Yitzhak Pilpel, Tamar Friedlander
Summary: This article investigates the fitness landscape of a yeast tRNA gene and finds that the wild type allele is sub-optimal. It also rules out the possibility that the wild type is the fittest on average or located on a local fitness maximum under four different conditions. The study further reveals that the wild type is mutationally robust, while more fit variants are typically mutationally fragile. Similar observations have been made in viral genomes.
MOLECULAR BIOLOGY AND EVOLUTION
(2022)
Editorial Material
Multidisciplinary Sciences
Martha W. Bagnall
Summary: Evidence from turtles and computer models suggests that rotational dynamics, a pattern of neuronal activity, determines locomotion, which challenges traditional models of motor control.
Editorial Material
Multidisciplinary Sciences
Alexander Goedel, Fredrik Lanner
Summary: The molecular mechanisms involved in human gastrulation, a crucial stage in early embryonic development, have been largely elusive, but gene-expression data from a gastrulating human embryo shed light on this process.
Editorial Material
Multidisciplinary Sciences
Marina. G. G. Guenza
Summary: Many biological processes rely on protein aggregates that have dynamic behaviors spanning different scales. A clever combination of spectroscopy and simulation can be used to investigate these diverse dynamics.
Article
Environmental Studies
Carola Strandberg
Summary: Residents play an integral role in place branding, but their perspectives and person-place bonds have often been overlooked. This study examines the mediating effects of self-congruity and place attachment on the relationship between residents' positive place image and their likelihood to stay. The findings demonstrate a positive relationship between place image and likelihood to stay, mediated by place attachment, and the mediating role of resident self-congruity. The implications suggest that resident image indirectly influences likelihood to stay through place attachment, highlighting the importance of inclusive community practices in place branding policies.
JOURNAL OF ENVIRONMENTAL PSYCHOLOGY
(2023)
News Item
Multidisciplinary Sciences
Nicky Phillips
Summary: Scientists expect the virus that causes COVID-19 to become endemic and pose less danger over time, according to a Nature survey.
Editorial Material
Multidisciplinary Sciences
Didier Mazel
Summary: This article introduces two previously unknown anti-plasmid systems in bacteria and explains how a cholera-causing bacterium eliminates plasmids.