Article
Medicine, General & Internal
Spyridon Vernadakis, Smaragdi Marinaki, Maria Darema, Ioanna Soukouli, Ioannis El. Michelakis, Chrysoula Beletsioti, Georgios Zavvos, Ioannis Bokos, Ioannis N. Boletis
Summary: Minimally invasive laparoscopic nephrectomy for living kidney donors resulted in shorter surgical duration, decreased length of hospital stay, and higher postoperative quality of life compared to open nephrectomy. The complication rates were similar, with a slight difference in surgical complications between the two groups.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Surgery
Jeong-Moo Lee, Ahmed Shehta, Kwang-Woong Lee, Suk Kyun Hong, Jae-Hyung Cho, Nam-Joon Yi, Kyung-Suk Suh
Summary: Living-donor safety and cosmetic outcome are the main concerns. Pure laparoscopic living-donor hepatectomy (PLLDH) can provide a balance. Donors operated by PLLDH have better satisfaction scores compared to conventional open approach.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Health Care Sciences & Services
Toshiki Hasegawa, Kouhei Nishikawa, Yuko Tamura, Tomoka Oka, Aiko Urawa, Saori Watanabe, Shugo Mizuno, Motohiro Okada
Summary: This study analyzed the decision-making process between PEKT and PDKT for kidney transplantation, revealing that the recipients' quality of life and emotional status were key factors influencing the decision, while the donors' quality of life and health status also played a role in shaping the outcome.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Ji-Hoon Sim, Hye-Mee Kwon, In-Gu Jun, Sung-Hoon Kim, Kyoung-Sun Kim, Young-Jin Moon, Jun-Gol Song, Gyu-Sam Hwang
Summary: This study found a significant association between donor sarcopenia and postoperative acute kidney injury following donor hepatectomy, with hypertension and synthetic colloid use also being significantly associated with postoperative AKI. However, donor sarcopenia was not a risk factor for delayed recovery of liver function.
LIVER INTERNATIONAL
(2022)
Article
Multidisciplinary Sciences
Pippa K. Bailey, Yoav Ben-Shlomo, Fergus J. Caskey, Mohammed Al-Talib, Hannah Lyons, Adarsh Babu, Liise K. Kayler, Lucy E. Selman
Summary: The study aimed to develop a UK-specific multicomponent intervention to support eligible individuals to access living-donor kidney transplant (LDKT). Through thematic analysis and qualitative interviews, potential themes including cultural and societal norms, family influence, resource limitation, and evidence of effectiveness were identified. A multicomponent intervention was developed based on existing interventions targeting mediators of inequity, adapted for acceptability and engagement in a UK population for evaluation in a future randomized controlled trial.
Article
Urology & Nephrology
Takahisa Hiramitsu, Toshihide Tomosugi, Kenta Futamura, Manabu Okada, Yutaka Matsuoka, Norihiko Goto, Toshihiro Ichimori, Shunji Narumi, Asami Takeda, Takaaki Kobayashi, Kazuharu Uchida, Yoshihiko Watarai
Summary: This study investigated the impact of age differences between older adult living donors and recipients on kidney transplantation outcomes. The results showed that kidney transplants from older adult donors to older adult recipients had the highest risk of graft loss and mortality, with recipients having lower estimated glomerular filtration rates.
KIDNEY INTERNATIONAL REPORTS
(2021)
Article
Biochemistry & Molecular Biology
G. J. Julia Huisman, Nora A. Spraakman, Jeroen V. Koomen, A. Marrit Talsma, Robert A. Pol, Stefan P. Berger, Henri G. D. Leuvenink, Michel M. R. F. Struys, Gertrude J. Nieuwenhuijs-Moeke
Summary: Early non-invasive detection and prediction of graft function after kidney transplantation is important. The study analyzed four urinary biomarkers and found that KIM-1 and NAG at early timepoints after transplantation were significant predictors for eGFR, while NGAL and NAG at day 1 after transplantation were negative predictors. Including these biomarkers improved the prediction models for graft outcome. Factors such as timing of measurement and transplantation factors need to be considered when using urinary biomarkers.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Surgery
L. Ebony Boulware, Debra L. Sudan, Tara S. Strigo, Patti L. Ephraim, Clemontina A. Davenport, Jane F. Pendergast, Iris Pounds, Jennie A. Riley, Margaret Falkovic, Aviel Alkon, Felicia Hill-Briggs, Ashley N. Cabacungan, Tyler M. Barrett, Dinushika Mohottige, Lisa McElroy, Clarissa J. Diamantidis, Matthew J. Ellis
Summary: The study found limited effectiveness of a transplant social worker intervention and financial assistance in activating potential donors among African Americans on the transplant waiting list.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Immunology
Fan Zhang, Saifu Yin, Yu Fan, Turun Song, Zhongli Huang, Jiayu Liang, Jiapei Wu, Youmin Yang, Tao Lin, Xianding Wang
Summary: This study found that the secretor status of both donors and recipients may have an impact on the outcomes of ABO incompatibility kidney transplantation. Recipients with weak secretor status may have better post-transplant renal function, while recipients from secretor donors had a lower incidence of graft rejection in the first year after transplantation.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Surgery
Robin K. Avery, Jennifer D. Motter, Kyle R. Jackson, Robert A. Montgomery, Allan B. Massie, Edward S. Kraus, Kieren A. Marr, Bonnie E. Lonze, Nada Alachkar, Mary J. Holechek, Darin Ostrander, Niraj Desai, Madeleine M. Waldram, Shmuel Shoham, Seema Mehta Steinke, Aruna Subramanian, Janet M. Hiller, Julie Langlee, Sheila Young, Dorry L. Segev, Jacqueline M. Garonzik Wang
Summary: Desensitization for incompatible living donor kidney transplantation increases the risk of infections, especially in highly desensitized recipients, leading to prolonged hospitalization and graft loss. Strategies are needed to protect patients from recurrent infections and extend the survival benefit of ILDKT.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Nutrition & Dietetics
Kao-Ming Hsu, Pei-Ru Lin, Ping-Fang Chiu, Yao-Peng Hsieh
Summary: This study investigated the subsequent renal function change following incident infectious diseases in living-donor liver transplant recipients. The results showed that hospitalization with major infections or pneumonia increased the risk of eGFR decline and adverse renal outcomes in these patients.
Article
Medicine, General & Internal
Martina Cozzi, Paola Donato, Gabriele Ugolini, Rostand Emmanuel Nguefouet Momo, Francesco Nacchia, Zeno Ballarini, Pierluigi Piccoli, Maurizio Cantini, Chiara Caletti, Stefano Andreola, Giorgio Gandini, Giovanni Gambaro, Luigino Boschiero
Summary: AB0 incompatible living donor kidney transplantation (AB0i LDKT) is an effective therapeutic strategy with graft function and survival comparable to compatible living donor kidney transplantation (AB0c LDKT), despite higher rates of acute rejection and sepsis. It provides an additional opportunity for patients with blood group 0.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Jun Young Lee, Sung Hwan Cha, Sung Hwa Kim, Kyung Hwan Jeong, Ku Yong Chung, Hong Rae Cho, Juhan Lee, Kyu Ha Huh, Jaeseok Yang, Myoung Soo Kim, Deok Gie Kim
Summary: The combination of ABO incompatibility and donor-recipient weight mismatch is an independent risk factor for graft and patient survival in living donor kidney transplantation, leading to an increased risk of pneumonia.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Surgery
Stijn C. van de Laar, Matthew L. Robb, Rachel Hogg, Lisa Burnapp, Vassilios E. Papalois, Frank J. M. F. Dor
Summary: The study found that LDKT performed within the UKLKSS had longer cold ischaemia time, higher incidence of delayed graft function, and lower graft function compared to the non-KEP group, but excellent 5-year graft survival similar to non-KEP was observed.
Article
Multidisciplinary Sciences
Aya Mizher, Heba Hammoudi, Farah Hamed, Abrar Sholi, Adham AbuTaha, Mazen A. Abdalla, Mohammad M. Jaber, Mohannad Hassan, Amer A. Koni, Sa'ed H. Zyoud
Summary: A cross-sectional study was conducted on hemodialysis patients, and the results showed that 47.1% of the patients reported chronic pain. Gender, social status, educational status, and number of chronic diseases were significantly related to pain severity. C-reactive protein and albumin were also significantly correlated with pain severity and interference.
SCIENTIFIC REPORTS
(2023)