Article
Psychiatry
J. F. Rodriguez-Testal, S. Fuentes-Marquez, C. Senin-Calderon, S. Fernandez-Leon, C. Ceballos Munuera, S. Perona-Garcelan, E. Fonseca-Pedrero
Summary: This study validated the Spanish Aberrant Salience Inventory (ASI) in adult and clinical populations. The results showed that both men and women, patients and nonclinical populations interpreted the items on ASI similarly. The distribution of scores by age suggested a developmental change in motivational response, stabilizing at around 19 years of age. The hypothesis that patients, particularly those diagnosed with schizophrenia, other psychotic disorders, and bipolar disorders, would have the highest average scores in aberrant salience was met.
COMPREHENSIVE PSYCHIATRY
(2022)
Article
Psychology, Clinical
Suzanne R. Neumann, Paul Glue, Richard J. Linscott
Summary: The study found that schizophrenia patients scored higher in aberrant salience and lower in adaptive salience, exhibiting more prominent aberrant salience and deficits in motivated behavior and reward processing. However, these differences in reward processing did not correlate with measures of aberrant salience.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Psychology, Multidisciplinary
Celia Ceballos-Munuera, Cristina Senin-Calderon, Sandra Fernandez-Leon, Sandra Fuentes-Marquez, Juan Fco Rodriguez-Testal
Summary: The study found that the relationship between IR and the psychotic dimension is partially mediated by AS and the disorganized dimension. The results also show that participant age significantly influences this relationship, while preoccupation about IR no longer plays a role.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychiatry
Lennart Christopher Schiwy, Caroline Garcia Forlim, Djo Juliette Fischer, Simone Kuehn, Maxi Becker, Juergen Gallinat
Summary: Cognitive deficits in schizophrenia and schizoaffective disorder are associated with aberrant functional connectivity in the default mode network (DMN) and salience network (SN). This study found that dysfunctional connectivity within the SN is important for cognitive deficits in psychosis, while connectivity in the DMN remains unchanged.
SCHIZOPHRENIA RESEARCH
(2022)
Article
Psychiatry
Leeann Akouri-Shan, Jason Schiffman, Zachary B. Millman, Caroline Demro, John Fitzgerald, Pamela J. Rakhshan Rouhakhtar, Samantha Redman, Gloria M. Reeves, Shuo Chen, James M. Gold, Elizabeth A. Martin, Cheryl Corcoran, Jonathan P. Roiser, Robert W. Buchanan, Laura M. Rowland, James A. Waltz
Summary: Research indicates that adaptive salience attribution in consummatory pleasure and social functioning is related in adolescents seeking help, and this relationship is mediated by impaired reward sensitivity and reinforcement learning.
SCHIZOPHRENIA BULLETIN
(2021)
Article
Psychiatry
Giulia Lisi, Andrea Raballo, Michele Ribolsi, Cinzia Niolu, Alberto Siracusano, Antonio Preti
Summary: The study aimed to investigate the level of aberrant salience in Italian high-school students, finding that aberrant salience is a common experience in adolescents and is associated with various psychopathological disorders, particularly thought disorders. This suggests that aberrant salience may be linked to proneness to psychosis.
EARLY INTERVENTION IN PSYCHIATRY
(2021)
Article
Hospitality, Leisure, Sport & Tourism
Fangxuan (Sam) Li, Qianqian Su
Summary: This study investigated the roles of novelty seeking and food authenticity in youth travellers' decision-making process at night markets using the MGB model. The results indicated that both novelty seeking and food authenticity have positive influences on decision-making.
CURRENT ISSUES IN TOURISM
(2022)
Article
Psychology, Clinical
Lorenzo Pelizza, Silvia Azzali, Sara Garlassi, Ilaria Scazza, Federica Paterlini, Luigi R. Chiri, Michele Poletti, Simona Pupo, David C. Cicero, Antonio Preti, Andrea Raballo
Summary: In a sample of young help-seekers, the AS Inventory showed high reliability and validity, with significant positive correlations with CAARMS Positive Symptoms subscores.
JOURNAL OF CLINICAL PSYCHOLOGY
(2021)
Review
Psychology, Clinical
John R. Purcell, Emma N. Herms, Jaime Morales, William P. Hetrick, Krista M. Wisner, Joshua W. Brown
Summary: The investigation of risky decision-making is important in clinical science, but the use of different behavioral tasks has led to a lack of agreement on risky decision-making within psychosis-spectrum disorders. This review analyzes the literature on behavioral risky decision-making to understand how specific task parameters contribute to differences in task performance and their associations with symptoms and cognitive functioning.
CLINICAL PSYCHOLOGY REVIEW
(2022)
Article
Psychiatry
Silvia Azzali, Lorenzo Pelizza, Ilaria Scazza, Federica Paterlini, Sara Garlassi, Luigi Rocco Chiri, Michele Poletti, Simona Pupo, Andrea Raballo
Summary: Aberrant salience (AS) is clinically relevant in individuals at ultra-high risk (UHR) of psychosis, and it appears to improve over time with the delivery of specialized psychosocial interventions for early psychosis.
SCHIZOPHRENIA RESEARCH
(2022)
Review
Medicine, General & Internal
Joachim Kowalski, Adrianna Aleksandrowicz, Malgorzata Dabkowska, Lukasz Gaweda
Summary: Cognitive biases play a crucial role in the development and severity of psychosis. Our review suggests that aberrant salience and source monitoring may share neural mechanisms, indicating their joint role in producing disrupted external attributions of perceptual and cognitive experiences in psychosis. Further studies are needed to explore the bridging mechanisms of these two biases.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Neurosciences
Amadeus Magrabi, Vera U. Ludwig, Christian M. Stoppel, Lena M. Paschke, David Wisniewski, Hauke R. Heekeren, Henrik Walter
Summary: Studies in decision neuroscience have found robust neural representations for the value of choice options. However, it is not well understood how the brain evaluates different attributes and combines them into overall values. This study used functional magnetic resonance imaging and found that attribute values were associated with activity in the posterior cingulate cortex, ventral striatum, and posterior inferior temporal gyrus, while overall values were represented in dorsolateral and ventromedial prefrontal cortex. Ultimately, this research suggests that certain brain regions are key for integrating attribute values and overall values.
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2022)
Article
Neurosciences
Ryan Sai-Ting Chu, Chung-Mun Ng, Kwun-Nam Chan, Kit-Wa Chan, Ho-Ming Lee, Lai-Ming Hui, Eric Chen, Wing-Chung Chang
Summary: The study found aberrant learned irrelevance (LIrr) in briefly-medicated first-episode schizophrenia-spectrum disorder (FES) patients, indicating impaired attention allocation to relevant versus irrelevant stimuli. These deficits were not correlated with positive symptom severity or other symptom dimensions in FES patients. Further research is needed to understand the longitudinal trajectory of LIrr deficits and their impact on treatment response in the early stages of illness.
Article
Psychiatry
Ilaria Scazza, Lorenzo Pelizza, Silvia Azzali, Sara Garlassi, Federica Paterlini, Luigi Rocco Chiri, Michele Poletti, Simona Pupo, Andrea Raballo
Summary: The study investigated the correlation of aberrant salience with functioning and psychopathology in young patients with first episode psychosis. It found that aberrant salience tends to decrease over time with the delivery of individual cognitive-behavioral therapy sessions in the same time period for FEP patients.
EARLY INTERVENTION IN PSYCHIATRY
(2022)
Article
Neurosciences
Yafei Tan, Ranran Yan, Yuan Gao, Meng Zhang, Georg Northoff
Summary: The study found significant overlap between interoception and decision making as well as emotion regulation, particularly in the right dorsal anterior insula. Both decision making and emotion regulation also showed conjunction-based activities in the dorsal anterior cingulate cortex (dACC). The identified insula showed a widespread coactivation pattern with other regions in the salience network.
Article
Neurosciences
Elaine J. Anderson, Marc S. Tibber, D. Sam Schwarzkopf, Sukhwinder S. Shergill, Emilio Fernandez-Egea, Geraint Rees, Steven C. Dakin
JOURNAL OF NEUROSCIENCE
(2017)
Article
Psychiatry
Cristina Martinelli, Francesco Rigoli, Sukhwinder S. Shergill
SCHIZOPHRENIA BULLETIN
(2017)
Article
Pharmacology & Pharmacy
Siobhan H. Gee, Sukhwinder S. Shergill, David M. Taylor
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY
(2017)
Article
Pharmacology & Pharmacy
George Joy, Eromona Whiskey, Mark Bolstridge, Alejandro Porras-Segovia, Theresa A. McDonagh, Carla M. Plymen, Sukhi S. Shergill
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
(2017)
Article
Medicine, Research & Experimental
Dan W. Joyce, Angie A. Kehagia, Derek K. Tracy, Jessica Proctor, Sukhwinder S. Shergill
JOURNAL OF TRANSLATIONAL MEDICINE
(2017)
Review
Psychology, Clinical
D. W. Joyce, D. K. Tracy, S. S. Shergill
PSYCHOLOGICAL MEDICINE
(2018)
Article
Medicine, Research & Experimental
Jenny Yiend, Antonella Trotta, Christopher Meek, Ilvana Dzafic, Nora Baldus, Bryony Crane, Thomas Kabir, Daniel Stahl, Margaret Heslin, Sukhwinder Shergill, Philip McGuire, Emmanuelle Peters
Article
Health Care Sciences & Services
Lilla Alexandra Porffy, Mitul A. Mehta, Joel Patchitt, Celia Boussebaa, Jack Brett, Teresa D'Oliveira, Elias Mouchlianitis, Sukhi S. Shergill
Summary: In this study, a novel virtual reality shopping task called VStore was developed and its construct validity was established by comparing it with the established computerized cognitive battery, Cogstate. The results showed that VStore is sensitive to age-related cognitive decline and engages standard cognitive domains.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Psychiatry
Richard A. Kanaan, Marco M. Picchioni, Colm McDonald, Sukhwinder S. Shergill, Philip K. McGuire
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2017)
Article
Psychiatry
Jessica Foster, John Lally, Victoria Bell, Sukhi Shergill
Article
Psychiatry
Alejandro Porras-Segovia, Amir Krivoy, Mark Horowitz, George Thomas, Mark Bolstridge, Dragos Ion, Sukhwinder S. Shergill
Article
Clinical Neurology
Natasza D. Orlov, Owen O'Daly, Derek K. Tracy, Yusuf Daniju, John Hodsoll, Lorena Valdearenas, John Rothwell, Sukhi S. Shergill
Article
Clinical Neurology
Natasza D. Orlov, Derek K. Tracy, Daniel Joyce, Shinal Patel, Joanna Rodzinka-Pasko, Hayley Dolan, John Hodsoll, Tracy Collier, John Rothwell, Sukhwinder S. Shergill
Article
Pharmacology & Pharmacy
Siobhan H. Gee, David M. Taylor, Sukhwinder S. Shergill, Robert Flanagan, James H. MacCabe
THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY
(2017)