Journal
SCANNING
Volume 36, Issue 1, Pages 2-10Publisher
WILEY-BLACKWELL
DOI: 10.1002/sca.21061
Keywords
surface analysis; metrology; life sciences; polishing technique; computer simulation
Categories
Funding
- Centre Technique des Industries Mecaniques
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In this study, two series of 11 samples of TiAl6V4 titanium alloy and 316L stainless steel have been polished in an isotropic manner at different levels in order to quantify the influence of biomaterial roughness on cell behavior. Topography was measured by a tactile profilometer and a multiscale analysis has been carried out. Human osteoblasts have been cultured on those samples. It appears that roughness has no reproducible effect on the cell behavior except an influence on cell orientation on the wider grooves. As a conclusion, biomaterial surface damage, in the roughness range between R-a = 0.01 and 0.1 m, has no influence on cell-adhesion mechanisms when roughness is isotropic and groove width is inferior to a critical value. SCANNING 36:2-10, 2014. (c) 2012 Wiley Periodicals, Inc.
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