Peptidylarginine deiminase-4 gene polymorphisms are associated with systemic lupus erythematosus and lupus nephritis

Changing patterns in clinical–histological presentation and renal outcome over the last five decades in a cohort of 499 patients with lupus nephritis

(2018) Gabriella Moroni et al.   ANNALS OF THE RHEUMATIC DISEASES

Blood pressure regulation by the angiotensin type 1 receptor in the proximal tubule

(2018) Marloes C. van Haaster et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Neutrophil peptidyl arginine deiminase-4 has a pivotal role in ischemia/reperfusion-induced acute kidney injury

(2018) Wesley M. Raup-Konsavage et al.   KIDNEY INTERNATIONAL

Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation

(2017) Mandar Bawadekar et al.   JOURNAL OF AUTOIMMUNITY

Acetylated Histones in Apoptotic Microparticles Drive the Formation of Neutrophil Extracellular Traps in Active Lupus Nephritis

(2017) Nils Rother et al.   Frontiers in Immunology

Update on Lupus Nephritis

(2016) Salem Almaani et al.   Clinical Journal of the American Society of Nephrology

Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response

(2016) Fatemeh Ghari et al.   Science Advances

Association between susceptibility to rheumatoid arthritis and PADI4 polymorphisms: a meta-analysis

(2015) Young Ho Lee et al.   CLINICAL RHEUMATOLOGY

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

(2015) Huw D Lewis et al.   Nature Chemical Biology

Genomic modulators of gene expression in human neutrophils

(2015) Vivek Naranbhai et al.   Nature Communications

Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lprmice

(2014) Jason S Knight et al.   ANNALS OF THE RHEUMATIC DISEASES

Histone Deimination As a Response to Inflammatory Stimuli in Neutrophils

(2014) I. Neeli et al.   JOURNAL OF IMMUNOLOGY

Single nucleotide polymorphisms in genes encoding toll-like receptors 7, 8 and 9 in Danish patients with systemic lupus erythematosus

(2014) C. Enevold et al.   MOLECULAR BIOLOGY REPORTS

Genetic polymorphisms of dsRNA ligating pattern recognition receptors TLR3, MDA5, and RIG-I. Association with systemic lupus erythematosus and clinical phenotypes

(2014) C. Enevold et al.   RHEUMATOLOGY INTERNATIONAL

Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus

(2013) Jason S. Knight et al.   JOURNAL OF CLINICAL INVESTIGATION

PADI2 Is Significantly Associated with Rheumatoid Arthritis

(2013) Xiaotian Chang et al.   PLoS One

Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus

(2013) Jonatan Leffler et al.   ARTHRITIS RESEARCH & THERAPY

Lupus neutrophils

(2012) Jason S. Knight et al.   CURRENT OPINION IN RHEUMATOLOGY

Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease

(2012) J. Leffler et al.   JOURNAL OF IMMUNOLOGY

Polymorphisms in peptidylarginine deiminase (PADI) associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis

(2012) Chun Lai Too et al.   ARTHRITIS RESEARCH & THERAPY

Autodeimination of Protein Arginine Deiminase 4 Alters Protein–Protein Interactions but Not Activity

(2011) Jessica L. Slack et al.   BIOCHEMISTRY

Genome-Wide Analysis Reveals PADI4 Cooperates with Elk-1 to Activate c-Fos Expression in Breast Cancer Cells

(2011) Xuesen Zhang et al.   PLoS Genetics

Synthesis-View: visualization and interpretation of SNP association results for multi-cohort, multi-phenotype data and meta-analysis

(2011) Sarah A Pendergrass et al.   BioData Mining

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

(2010) Pingxin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population

(2009) M. L. Burr et al.   ANNALS OF THE RHEUMATIC DISEASES

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Multiple sclerosis and polymorphisms of innate pattern recognition receptors TLR1-10, NOD1-2, DDX58, and IFIH1

(2009) Christian Enevold et al.   JOURNAL OF NEUROIMMUNOLOGY

A Functional Haplotype of PADI4 Gene in Rheumatoid Arthritis: Positive Correlation in a French Population

(2009) F. GANDJBAKHCH et al.   JOURNAL OF RHEUMATOLOGY