Severe acute polyarthritis in a child after high doses of moxifloxacin

Clinically severe, acute polyarthritis, associated with high doses of oral moxifloxacin, has been documented for the first time in a 12-y-old child. MR studies revealed massive joint effusion, as well as moderate ligament and cartilage damage. On follow-up, neither long-term sequelae nor functional impairment of the involved joints was observed.