High-Mobility Group Box 1 Inhibition Alleviates Lupus-Like Disease in BXSB Mice

Lupus antibodies to the HMGB1 chromosomal protein: epitope mapping and association with disease activity

(2014) Ayako Hayashi et al.   Modern Rheumatology

P2X7Blockade Attenuates Murine Lupus Nephritis by Inhibiting Activation of the NLRP3/ASC/Caspase 1 Pathway

(2013) Jijun Zhao et al.   ARTHRITIS AND RHEUMATISM

Self Double-Stranded (ds)DNA Induces IL-1  Production from Human Monocytes by Activating NLRP3 Inflammasome in the Presence of Anti-dsDNA Antibodies

(2013) M. S. Shin et al.   JOURNAL OF IMMUNOLOGY

An Essential Role of Caspase 1 in the Induction of Murine Lupus and Its Associated Vascular Damage

(2013) J. Michelle Kahlenberg et al.   Arthritis & Rheumatology

Bone marrow-derived and synovium-derived mesenchymal cells promote Th17 cell expansion and activation through caspase 1 activation: Contribution to the chronicity of rheumatoid arthritis

(2012) Assia Eljaafari et al.   ARTHRITIS AND RHEUMATISM

Long-term safety profile of belimumab plus standard therapy in patients with systemic lupus erythematosus

(2012) Joan T. Merrill et al.   ARTHRITIS AND RHEUMATISM

High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases

(2012) Wei Yan et al.   HEPATOLOGY

U1-Small Nuclear Ribonucleoprotein Activates the NLRP3 Inflammasome in Human Monocytes

(2012) M. S. Shin et al.   JOURNAL OF IMMUNOLOGY

Neutrophil Extracellular Trap-Associated Protein Activation of the NLRP3 Inflammasome Is Enhanced in Lupus Macrophages

(2012) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

Fecal HMGB1 Is a Novel Marker of Intestinal Mucosal Inflammation in Pediatric Inflammatory Bowel Disease

(2011) Roberta Vitali et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

CXCR3 promotes the production of IgG1 autoantibodies but is not essential for the development of lupus nephritis in NZB/NZW mice

(2011) Katrin Moser et al.   ARTHRITIS AND RHEUMATISM

Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model

(2010) Therese Östberg et al.   ARTHRITIS AND RHEUMATISM

HMGB1, a potent proinflammatory cytokine in sepsis

(2010) Wenchang Huang et al.   CYTOKINE

HMGB1: A Dangerous Player in Lupus Pathogenesis

(2010) D. S. PISETSKY   JOURNAL OF RHEUMATOLOGY

Expression of High Mobility Group Box Chromosomal Protein 1 and Its Modulating Effects on Downstream Cytokines in Systemic Lupus Erythematosus

(2010) J. LI et al.   JOURNAL OF RHEUMATOLOGY

RAGE-independent autoreactive B cell activation in response to chromatin and HMGB1/DNA immune complexes

(2009) Ana M. Avalos et al.   AUTOIMMUNITY

Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis

(2008) Takashi Hamada et al.   ARTHRITIS AND RHEUMATISM

Pathogenic anti-DNA antibodies modulate gene expression in mesangial cells: Involvement of HMGB1 in anti-DNA antibody-induced renal injury

(2008) Xiaoping Qing et al.   IMMUNOLOGY LETTERS

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE