Article
Environmental Sciences
Jia-Yue Zeng, Yu Miao, Chong Liu, Yan-Ling Deng, Pan-Pan Chen, Min Zhang, Fei-Peng Cui, Tian Shi, Ting-Ting Lu, Chang-Jiang Liu, Qiang Zeng
Summary: This study explored the associations between multiple exposures to organochlorine pesticides (OCPs) and serum testosterone concentrations among Chinese men. The results suggest that elevated dieldrin and p, p'-DDD levels may be associated with altered testosterone concentrations.
Article
Nutrition & Dietetics
Zhizhong Zhang, Mengmeng Wang, Shuai Yuan, Xinfeng Liu
Summary: The study suggests that alcohol intake may increase the risk of epilepsy, while milk intake may lower the risk.
Article
Psychiatry
Lingsi Zeng, Honggang Lv, Juan Li, Ranran Xue, Xia Liu, Cong Zhou, Hao Yu
Summary: This study revealed correlations between smoking initiation and coffee consumption with reduced blood levels of clozapine and norclozapine, providing guidance for clinicians in adjusting clozapine levels for treated patients.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Oncology
Takuya Imatoh, Norie Sawada, Taiki Yamaji, Motoki Iwasaki, Manami Inoue, Shoichiro Tsugane
Summary: A study in Japan found that there is no association between coffee consumption and prostate cancer risk in Japanese men, whether for total, localized, or advanced cancer. This suggests that coffee does not have a protective effect against prostate cancer in this population.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Anesthesiology
Shuai Yuan, Iyas Daghlas, Susanna C. Larsson
Summary: This study used Mendelian randomization to investigate the causal associations between alcohol and coffee consumption, smoking, and the risk of developing migraine. The results suggested that genetically predicted alcohol consumption and coffee consumption were negatively associated with migraine risk, while smoking initiation was positively associated. The study also found that genetic liability to migraine was inversely associated with alcohol consumption, but not with coffee consumption or smoking initiation.
Article
Multidisciplinary Sciences
Kyoko Kondo, Kanzo Suzuki, Masakazu Washio, Satoko Ohfuji, Satoru Adachi, Sakae Kan, Seiichiro Imai, Kunihiko Yoshimura, Naoyuki Miyashita, Nobumitsu Fujisawa, Akiko Maeda, Wakaba Fukushima, Yoshio Hirota
Summary: A large prospective cohort study in the United States found an inverse association between pneumonia and influenza deaths and coffee intake. In Japan, where the mortality rate of pneumonia in elderly people is high, a hospital-based case control study investigated the association between coffee and green tea intake and pneumonia among the elderly. The study suggested a preventive association between coffee intake over 2 cups per day and pneumonia in the elderly.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
Zhengtao Lv, Jiarui Cui, Jiaming Zhang
Summary: This study used Mendelian Randomization (MR) method to assess the causal relationships between smoking initiation, alcohol consumption, coffee consumption and the risk of Low Back Pain (LBP). The results showed that smoking initiation is causally associated with an increased risk of LBP, while there is no causal effect of alcohol and coffee consumption on LBP. This study provides important insights for the management and treatment of LBP patients.
EUROPEAN SPINE JOURNAL
(2022)
Article
Medicine, General & Internal
Peter Lemmer, Paul Manka, Jan Best, Alisan Kahraman, Julia Kaelsch, Ramiro Vilchez-Vargas, Alexander Link, Hsin Chiang, Guido Gerken, Ali Canbay, Lars P. Bechmann, Svenja Sydor
Summary: Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are leading causes of chronic liver diseases worldwide. While clinically distinguished by alcohol consumption, NAFLD coexists with moderate alcohol consumption in a growing proportion of the population. Studies have shown that even moderate alcohol consumption has impacts on liver injury, lipid metabolism, and the composition of gut microbiota.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Sabrina Ahmed, Takashi Hisamatsu, Aya Kadota, Akira Fujiyoshi, Hiroyoshi Segawa, Sayuki Torii, Naoyuki Takashima, Keiko Kondo, Yoshihisa Nakagawa, Hirotsugu Ueshima, Katsuyuki Miura
Summary: This study aimed to assess the frequency and associated factors of ventricular premature complexes (VPCs) in healthy general Japanese men. The study found that age, height, resting heart rate, diabetes mellitus, hypertension, physical activity, smoking, alcohol consumption, and lipid-lowering therapy were independently associated with VPCs frequency.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Article
Endocrinology & Metabolism
Jing Song, Wei-Qian Lin
Summary: This study found that heavy alcohol consumption was independently associated with an increased risk of new-onset type 2 diabetes in Japanese men, while the association between moderate or light alcohol consumption and diabetes incidence was not clear.
BMC ENDOCRINE DISORDERS
(2023)
Article
Multidisciplinary Sciences
Inhae Sohn, Chol Shin, Inkyung Baik
Summary: The study evaluated the association between green tea, coffee, and soft drink consumption and changes in leukocyte telomere length (LTL) over 6 years. The results showed a negative association between green tea consumption and LTL shortening, specifically in women. On the other hand, soft drink consumption was positively associated with LTL shortening in women. Coffee consumption did not show any significant association with LTL changes.
SCIENTIFIC REPORTS
(2023)
Article
Peripheral Vascular Disease
Noriko Sakiyama, Kiyohide Tomooka, Koutatsu Maruyama, Tomokazu Tajima, Manami Kimura, Setsuko Sato, Motoki Endo, Ai Ikeda, Ryutaro Shirahama, Hiroo Wada, Takeshi Tanigawa
Summary: This study found that Japanese male bus drivers with both sleep-disordered breathing and excessive alcohol consumption are at a higher risk of hypertension. Simultaneous management of sleep-disordered breathing and alcohol consumption is crucial in preventing hypertension among bus drivers.
HYPERTENSION RESEARCH
(2021)
Article
Substance Abuse
Ali Haidar Syaifullah, Akihiko Shiino, Akira Fujiyoshi, Aya Kadota, Keiko Kondo, Takahiro Ito, Hiroyoshi Segawa, Mohammad Moniruzzaman, Takashi Waki, Naoko Miyagawa, Ikuo Tooyama, Hirotsugu Ueshima, Katsuyuki Miura
Summary: The study investigated the relationship between alcohol consumption and brain gray matter volume in community-dwelling Japanese men, revealing lower GMV in heavy drinkers and higher white matter lesion volume associated with alcohol consumption.
Article
Psychiatry
Asmaa Yehia, Ricardo A. L. Sousa, Osama A. A. Abulseoud
Summary: There is a sex difference in alcohol use disorder (AUD) due to distinctive neurobiological responses between men and women, which requires further investigation for personalized management.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Toxicology
Yoo Jeong Lee, Hansongyi Lee, Han Byul Jang, Min-Gyu Yoo, Sumin Im, Soo Kyung Koo, Hye-Ja Lee
Summary: Excessive alcohol intake is a major public health problem in East Asian countries. This study found that genetic factors, specifically three single-nucleotide polymorphisms (SNPs) within the HECTD4 gene, are significantly associated with alcohol consumption and the risk of type 2 diabetes. The study also showed that individuals carrying the variant allele in these SNPs had lower levels of fasting blood glucose, triglyceride, and GGT. Furthermore, the study discovered that ethanol increased the expression of HECTD4, but this effect was decreased by NAC treatment.
ARCHIVES OF TOXICOLOGY
(2022)