Assessment of hydroxylated metabolites of polychlorinated biphenyls as potential xenoestrogens: a QSAR comparative analysis∗

Prediction of Organ Toxicity Endpoints by QSAR Modeling Based on Precise Chemical-Histopathology Annotations

(2012) Eugene Myshkin et al.   Chemical Biology & Drug Design

Docking and QSAR study on the binding interactions between polycyclic aromatic hydrocarbons and estrogen receptor

(2012) Fei Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

A QSAR Study of Environmental Estrogens Based on a Novel Variable Selection Method

(2012) Zhongsheng Yi et al.   MOLECULES

Biotransformation of 2,2′,5,5′-Tetrachlorobiphenyl (PCB 52) and 3,3′,4,4′-Tetrachlorobiphenyl (PCB 77) by Liver Microsomes from Four Species of Sea Turtles

(2011) Kristine L. Richardson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Polychlorinated biphenyls and their hydroxylated metabolites in placenta from Madrid mothers

(2011) Belén Gómara et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

QSAR model reproducibility and applicability: A case study of rate constants of hydroxyl radical reaction models applied to polybrominated diphenyl ethers and (benzo-)triazoles

(2011) Partha Pratim Roy et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Evaluation of the OECD (Q)SAR Application Toolbox for the profiling of estrogen receptor binding affinities

(2011) E. Mombelli   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans

(2011) Shinji Takeuchi et al.   TOXICOLOGY

Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO2-PCBs

(2011) Elsa C. Antunes-Fernandes et al.   TOXICOLOGY LETTERS

CAESAR models for developmental toxicity

(2010) Antonio Cassano et al.   Chemistry Central Journal

Hydroxylated polychlorinated biphenyls (OH-PCBs) induce vitellogenin through estrogenic activity in primary-cultured hepatocytes of the Xenopus laevis

(2010) Kei Nomiyama et al.   CHEMOSPHERE

Evaluation of the OECD QSAR Application Toolbox and Toxtree for estimating the mutagenicity of chemicals. Part 1. Aromatic amines

(2010) J. Devillers et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Evaluation of the OECD (Q)SAR Application Toolbox and Toxtree for predicting and profiling the carcinogenic potential of chemicals

(2010) E. Mombelli et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

The European Union’s REACH regulation: a review of its history and requirements

(2009) E. Spencer Williams et al.   CRITICAL REVIEWS IN TOXICOLOGY

Hydroxylated PCB metabolites (OH-PCBs) in archived serum from 1950–60s California mothers: A pilot study

(2009) J.S. Park et al.   ENVIRONMENT INTERNATIONAL

Exposure to Hydroxylated Polychlorinated Biphenyls (OH-PCBs) in the Prenatal Period and Subsequent Neurodevelopment in Eastern Slovakia

(2009) Hye-Youn Park et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Distribution of PCBs, Their Hydroxylated Metabolites, and Other Phenolic Contaminants in Human Serum from Two European Countries†

(2009) Alin C. Dirtu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Computational toxicology: an overview of the sources of data and of modelling methods

(2009) Florian Nigsch et al.   Expert Opinion on Drug Metabolism & Toxicology

The importance of molecular structures, endpoints’ values, and predictivity parameters in QSAR research: QSAR analysis of a series of estrogen receptor binders

(2009) Jiazhong Li et al.   MOLECULAR DIVERSITY

Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells

(2009) Anne Dreiem et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mono-hydroxylated polychlorinated biphenyls are potent aryl hydrocarbon receptor ligands in recombinant yeast cells

(2009) Ryo Kamata et al.   TOXICOLOGY IN VITRO

Hydroxylated polychlorinated biphenyls (OH-PCBs) in the blood of mammals and birds from Japan: Lower chlorinated OH-PCBs and profiles

(2008) Tatsuya Kunisue et al.   CHEMOSPHERE

Chiral Polychlorinated Biphenyls Are Biotransformed Enantioselectively by Mammalian Cytochrome P-450 Isozymes to Form Hydroxylated Metabolites

(2008) Nicholas A. Warner et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Critical Assessment of QSAR Models of Environmental Toxicity againstTetrahymena pyriformis:Focusing on Applicability Domain and Overfitting by Variable Selection

(2008) Igor V. Tetko et al.   Journal of Chemical Information and Modeling

Binary classification models for endocrine disrupter effects mediated through the estrogen receptor†

(2008) A. Roncaglioni et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Alterations in gene expression of glutamate receptors and exocytosis-related factors by a hydroxylated-polychlorinated biphenyl in the developing rat brain

(2008) Masaki Takahashi et al.   TOXICOLOGY

Prediction of the health effects of polychlorinated biphenyls (PCBs) and their metabolites using quantitative structure–activity relationship (QSAR)☆☆☆

(2008) P. Ruiz et al.   TOXICOLOGY LETTERS

Polychlorinated biphenyls (PCBs) and hydroxy-PCBs in adipose tissue of women in Southeast Spain

(2007) M.F. Fernandez et al.   CHEMOSPHERE

Effects of estradiol, PCB3, and their hydroxylated metabolites on proliferation, cell cycle, and apoptosis of human breast cancer cells

(2007) Ewa L. Gregoraszczuk et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY