Functionalyzed Polyampholytes on the Basis of Copolymers of N,N-Diallyl-N,N-dimethylammonium Chloride and Maleic Acid

Polyampholytes were prepared by radical copolymerization of N,N-diallyl-N,N-dimethylammonium chloride and maleic acid. The esterification and subsequent hydrazinolysis permitted to introduce hydrazide groups capable of formation of the coordination bond with copper ions. The formation of complex between the hydrazide groups of polyampholyte and Cu2+ ions was established by electronic spectroscopy. It was shown that the coordination of two hydrazide groups in the complex was hampered because of the polymeric nature of the ligand. It is shown that the created functionalized polyampholytes exhibit fungiostatic activity. The highest inhibiting effect on the growth of the pathogenic fungus Fusarium oxysporum is observed for complexes of the hydrazide-containing polyampholytes with Cu2+ ions.