4.5 Review

Magnetic nanoparticles - DNA interactions: design and applications of nanobiohybrid systems

Journal

RUSSIAN CHEMICAL REVIEWS
Volume 83, Issue 4, Pages 299-322

Publisher

TURPION LTD
DOI: 10.1070/RC2014v083n04ABEH004412

Keywords

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Funding

  1. Ministry of Education and Science of the Russian Federation [14.512.11.0030, 3.1344.2014]
  2. Russian Foundation for Basic Research [13-04-98040, 14-04-31224]

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Mechanisms of interaction between nucleic acid molecules and magnetic nanoparticles and methods of their conjugation in order to develop functional nanostructures are considered. The properties of nucleic acids and magnetic nanoparticles that are key to the design of nanobiocomposites are described. Prospects for applications of nanobiocomposites in nanoelectronics and medicine are analyzed. Possible harmful effects of magnetic nanoparticles on the genetic system are briefly outlined. The bibliography includes 287 references.

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