Journal
RUSSIAN CHEMICAL BULLETIN
Volume 59, Issue 12, Pages 2302-2308Publisher
SPRINGER
DOI: 10.1007/s11172-010-0392-9
Keywords
cobalt complexes; carboranes; oxonium compounds; amino acids; tyrosine; boron neutron capture therapy of cancer
Categories
Funding
- Russian Foundation for Basic Research [08-03-00463, 09-03-00701, 10-03-00698]
- Presidium of the Russian Academy of Sciences
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A novel approach to the synthesis of boron-containing amino acids based on ring opening of cyclic oxonium derivatives of polyhedral boron hydrides under the action of the terminal functional groups of natural amino acids was proposed. This approach was successfully implemented for the synthesis of cobalt bis(dicarbollide) - tyrosine conjugate.
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