Liver-specific microRNA-122: Biogenesis and function

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

(2011) Mirco Castoldi et al.   JOURNAL OF CLINICAL INVESTIGATION

Positive regulation of hepatic miR-122 expression by HNF4α

(2011) Zhen-Ya Li et al.   JOURNAL OF HEPATOLOGY

CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation

(2011) David M. Burns et al.   NATURE

miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components

(2011) Ashley P. E. Roberts et al.   NUCLEIC ACIDS RESEARCH

Masking the 5' terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex

(2011) E. S. Machlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

miR-122 does not modulate the elongation phase of hepatitis C virus RNA synthesis in isolated replicase complexes

(2010) Rodrigo A. Villanueva et al.   ANTIVIRAL RESEARCH

A comprehensive survey of 3' animal miRNA modification events and a possible role for 3' adenylation in modulating miRNA targeting effectiveness

(2010) A. M. Burroughs et al.   GENOME RESEARCH

Regulation of Hepatitis C Virus Translation and Infectious Virus Production by the MicroRNA miR-122

(2010) R. K. Jangra et al.   JOURNAL OF VIROLOGY

Human Ago2 Is Required for Efficient MicroRNA 122 Regulation of Hepatitis C Virus RNA Accumulation and Translation

(2010) J. A. Wilson et al.   JOURNAL OF VIROLOGY

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

MiR-122/Cyclin G1 Interaction Modulates p53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells

(2009) F. Fornari et al.   CANCER RESEARCH

Integration of microRNA miR-122 in hepatic circadian gene expression

(2009) D. Gatfield et al.   GENES & DEVELOPMENT

Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2

(2009) T. Katoh et al.   GENES & DEVELOPMENT

MicroRNA-122 Inhibits Tumorigenic Properties of Hepatocellular Carcinoma Cells and Sensitizes These Cells to Sorafenib

(2009) Shoumei Bai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of Hepatitis C Virus RNA Abundance and the Isoprenoid Biosynthesis Pathway by MicroRNA miR-122 Involves Distinct Mechanisms

(2009) K. L. Norman et al.   JOURNAL OF VIROLOGY

Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy

(2009) Magdalena Sarasin-Filipowicz et al.   NATURE MEDICINE

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties

(2009) C Coulouarn et al.   ONCOGENE

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

Position-Dependent Function for a Tandem MicroRNA miR-122-Binding Site Located in the Hepatitis C Virus RNA Genome

(2008) Catherine L. Jopling et al.   Cell Host & Microbe

microRNA-122 stimulates translation of hepatitis C virus RNA

(2008) Jura Inga Henke et al.   EMBO JOURNAL

MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma

(2008) Wei-Chih Tsai et al.   HEPATOLOGY

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE