NGF/TrkA Signaling as a Therapeutic Target for Pain

Molecular players of tumor–nerve interactions

(2015) Deepitha Selvaraj et al.   PAIN

Orthopedic surgery and bone fracture pain are both significantly attenuated by sustained blockade of nerve growth factor

(2015) Lisa A. Majuta et al.   PAIN

Maximizing Diversity from a Kinase Screen: Identification of Novel and Selective pan-Trk Inhibitors for Chronic Pain

(2014) Shawn J. Stachel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mirror-image pain is mediated by nerve growth factor produced from tumor necrosis factor alpha-activated satellite glia after peripheral nerve injury

(2014) Chau-Fu Cheng et al.   PAIN

The role of nerve growth factor and its receptors in tumorigenesis and cancer pain

(2014) Wenfang Wang et al.   BioScience Trends

The prevalence of chronic pain with an analysis of countries with a Human Development Index less than 0.9: a systematic review without meta-analysis

(2012) Raga A. Elzahaf et al.   CURRENT MEDICAL RESEARCH AND OPINION

Effects of TrkA inhibitory peptide on cancer-induced pain in a mouse melanoma model

(2012) Mari Tabata et al.   Journal of Anesthesia

Lidocaine treatment during synapse reformation periods permanently inhibits NGF-induced excitation in an identified reconstructed synapse of Lymnaea stagnalis

(2011) Shin Onizuka et al.   Journal of Anesthesia

APP is Phosphorylated by TrkA and Regulates NGF/TrkA Signaling

(2011) C. Matrone et al.   JOURNAL OF NEUROSCIENCE

Fate of novel painkiller mAbs hangs in balance

(2011) Ken Garber   NATURE BIOTECHNOLOGY

A Synthetic Cell-Penetrating Peptide Antagonizing TrkA Function Suppresses Neuropathic Pain in Mice

(2010) Wei-Ying Ma et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Local Administration of a Synthetic Cell-Penetrating Peptide Antagonizing TrkA Function Suppresses Inflammatory Pain in Rats

(2010) Koyo Ueda et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Administration of a Tropomyosin Receptor Kinase Inhibitor Attenuates Sarcoma-Induced Nerve Sprouting, Neuroma Formation and Bone Cancer Pain

(2010) Joseph R Ghilardi et al.   Molecular Pain

Blockade of nerve sprouting and neuroma formation markedly attenuates the development of late stage cancer pain

(2010) W.G. Mantyh et al.   NEUROSCIENCE

Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee

(2010) Nancy E. Lane et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Neuroscience: One hundred years of Rita

(2009) Alison Abbott   NATURE

Treating skeletal pain: limitations of conventional anti-inflammatory drugs and anti-neurotrophic factor as a possible alternative

(2009) Cory J Xian et al.   Nature clinical practice. Rheumatology

Expression Profile of Nerve Growth Factor after Muscle Incision in the Rat

(2008) Chaoran Wu et al.   ANESTHESIOLOGY

Targeting Nerve Growth Factor in Pain

(2008) Judy J Watson et al.   BIODRUGS

Effect of Synthetic Cell-Penetrating Peptides on TrkA Activity in PC12 Cells

(2008) Munetaka Hirose et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Peripheral Mechanisms of Neuropathic Pain — Involvement of Lysophosphatidic Acid Receptor-Mediated Demyelination

(2008) Hiroshi Ueda   Molecular Pain

The Kyoto protocol of IASP Basic Pain Terminology☆

(2008) John D. Loeser et al.   PAIN