Journal
RHEUMATOLOGY INTERNATIONAL
Volume 34, Issue 11, Pages 1613-1614Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00296-013-2890-1
Keywords
The toll-like receptor-4 signaling; Rheumatoid arthritis; Pro-inflammatory cytokines
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The Toll-like receptor-4 signaling (TLR-4) has been found to be over-expressed in rheumatoid arthritis (RA) synovium. Furthermore, it regulates the expression of pro-inflammatory cytokines. Based on the current evidences, TLR-4 may be a new potential therapeutic pathway for RA.
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