Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of  2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis

A non-complement-fixing antibody to  2 glycoprotein I as a novel therapy for antiphospholipid syndrome

(2014) C. Agostinis et al.   BLOOD

The Pathogenesis of the Antiphospholipid Syndrome

(2013) Bill Giannakopoulos et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autoantibodies specific to a peptide of  2-glycoprotein I cross-react with TLR4, inducing a proinflammatory phenotype in endothelial cells and monocytes

(2012) T. Colasanti et al.   BLOOD

C6 knock-out mice are protected from thrombophilia mediated by antiphospholipid antibodies

(2012) AL Carrera-Marín et al.   LUPUS

Current International Initiatives in Antiphospholipid Antibody Testing

(2012) Rohan Willis et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Evaluating the conformation of recombinant domain I of β2-glycoprotein I and its interaction with human monoclonal antibodies

(2011) Charis Pericleous et al.   MOLECULAR IMMUNOLOGY

Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome

(2010) Z. Romay-Penabad et al.   BLOOD

New therapeutic targets for the antiphospholipid syndrome

(2010) Charis Pericleous et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Thrombin Binding Predicts the Effects of Sequence Changes in a Human Monoclonal Antiphospholipid Antibody on Its In Vivo Biologic Actions

(2009) I. Giles et al.   JOURNAL OF IMMUNOLOGY

In vivoinhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of β2-glycoprotein I: proof of concept

(2009) Y. IOANNOU et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter study

(2009) B. DE LAAT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS