The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA: Table 1

Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity

(2014) Buhm Han et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides

(2014) L Bossini-Castillo et al.   ANNALS OF THE RHEUMATIC DISEASES

High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci

(2014) Kwangwoo Kim et al.   ANNALS OF THE RHEUMATIC DISEASES

Autoimmunity-Associated LYP-W620 Does Not Impair Thymic Negative Selection of Autoreactive T Cells

(2014) Dennis J. Wu et al.   PLoS One

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk

(2013) Annie Yarwood et al.   ANNALS OF THE RHEUMATIC DISEASES

Using lifestyle factors to identify individuals at higher risk of inflammatory polyarthritis (results from the European Prospective Investigation of Cancer-Norfolk and the Norfolk Arthritis Register—the EPIC-2-NOAR Study)

(2013) Manjari Lahiri et al.   ANNALS OF THE RHEUMATIC DISEASES

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins

(2013) Aase Haj Hensvold et al.   ANNALS OF THE RHEUMATIC DISEASES

Brief Report: Identification ofBACH2andRAD51Bas Rheumatoid Arthritis Susceptibility Loci in a Meta-Analysis of Genome-Wide Data

(2013) Kate McAllister et al.   ARTHRITIS AND RHEUMATISM

Relatives Without Rheumatoid Arthritis Show Reactivity to Anti-Citrullinated Protein/Peptide Antibodies That Are Associated With Arthritis-Related Traits: Studies of the Etiology of Rheumatoid Arthritis

(2013) Kendra A. Young et al.   ARTHRITIS AND RHEUMATISM

Familial Risks and Heritability of Rheumatoid Arthritis: Role of Rheumatoid Factor/Anti-Citrullinated Protein Antibody Status, Number and Type of Affected Relatives, Sex, and Age

(2013) Thomas Frisell et al.   ARTHRITIS AND RHEUMATISM

First-degree Relatives of Patients with Rheumatoid Arthritis Exhibit High Prevalence of Joint Symptoms

(2013) I. Smolik et al.   JOURNAL OF RHEUMATOLOGY

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

(2013) Karen A. Hunt et al.   NATURE

Identification of the Tyrosine-Protein Phosphatase Non-Receptor Type 2 as a Rheumatoid Arthritis Susceptibility Locus in Europeans

(2013) Joanna E. Cobb et al.   PLoS One

Patients with early arthritis consume less alcohol than controls, regardless of the type of arthritis

(2013) A. L. Huidekoper et al.   RHEUMATOLOGY

Association of Environmental and Genetic Factors and Gene-Environment Interactions With Risk of Developing Rheumatoid Arthritis

(2013) Elizabeth W. Karlson et al.   ARTHRITIS CARE & RESEARCH

Predicting the Risk of Rheumatoid Arthritis and Its Age of Onset through Modelling Genetic Risk Variants with Smoking

(2013) Ian C. Scott et al.   PLoS Genetics

Novel Rheumatoid Arthritis Susceptibility Locus at 22q12 Identified in an Extended UK Genome-Wide Association Study

(2013) Gisela Orozco et al.   Arthritis & Rheumatology

Features of the Synovium of Individuals at Risk of Developing Rheumatoid Arthritis: Implications for Understanding Preclinical Rheumatoid Arthritis

(2013) M. J. H. de Hair et al.   Arthritis & Rheumatology

Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients

(2012) Sebastien Viatte et al.   ANNALS OF THE RHEUMATIC DISEASES

A prediction rule for the development of arthritis in seropositive arthralgia patients

(2012) Lotte Arwen van de Stadt et al.   ANNALS OF THE RHEUMATIC DISEASES

Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the ‘AMC-Senshu’ method

(2012) Jing Shi et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile

(2012) Karin Lundberg et al.   ANNALS OF THE RHEUMATIC DISEASES

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

(2012) Danielle M Gerlag et al.   ANNALS OF THE RHEUMATIC DISEASES

Familial clustering of the serum cytokine profile in the relatives of rheumatoid arthritis patients

(2012) Hani S. El-Gabalawy et al.   ARTHRITIS AND RHEUMATISM

Investigation of Rheumatoid Arthritis Genetic Susceptibility Markers in the Early Rheumatoid Arthritis Study Further Replicates the TRAF1 Association with Radiological Damage

(2012) S. VIATTE et al.   JOURNAL OF RHEUMATOLOGY

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

(2012) Steve Eyre et al.   NATURE GENETICS

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

(2012) Yukinori Okada et al.   NATURE GENETICS

Emerging patterns of genetic overlap across autoimmune disorders

(2012) Corinne Richard-Miceli et al.   Genome Medicine

Citrullination of autoantigens: Upstream of TNFα in the pathogenesis of rheumatoid arthritis

(2011) Anne-Marie Quirke et al.   FEBS LETTERS

Non-HLA genes modulate the risk of rheumatoid arthritis associated with HLA-DRB1 in a susceptible North American Native population

(2011) H S El-Gabalawy et al.   GENES AND IMMUNITY

The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population

(2011) Chikashi Terao et al.   HUMAN MOLECULAR GENETICS

The autoimmune disease–associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness

(2011) Jinyi Zhang et al.   NATURE GENETICS

Are ACPA-positive and ACPA-negative RA the same disease?

(2011) Nina A. Daha et al.   Nature Reviews Rheumatology

Genetic Risk Score Predicting Risk of Rheumatoid Arthritis Phenotypes and Age of Symptom Onset

(2011) Lori B. Chibnik et al.   PLoS One

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

(2011) J. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis

(2010) D. van der Woude et al.   ANNALS OF THE RHEUMATIC DISEASES

Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk

(2010) E. W. Karlson et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetic variants in the prediction of rheumatoid arthritis

(2010) A. H. M. van der Helm-van Mil et al.   ANNALS OF THE RHEUMATIC DISEASES

The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia

(2010) L. A. van de Stadt et al.   ANNALS OF THE RHEUMATIC DISEASES

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus

(2010) G. Orozco et al.   ANNALS OF THE RHEUMATIC DISEASES

2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) D. Aletaha et al.   ANNALS OF THE RHEUMATIC DISEASES

Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: A meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein

(2010) Diane van der Woude et al.   ARTHRITIS AND RHEUMATISM

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

(2010) Kai Wang et al.   HUMAN MOLECULAR GENETICS

Autoimmune-associated PTPN22 R620W Variation Reduces Phosphorylation of Lymphoid Phosphatase on an Inhibitory Tyrosine Residue

(2010) Edoardo Fiorillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility

(2010) Yuta Kochi et al.   NATURE GENETICS

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register

(2010) Darren Plant et al.   RHEUMATOLOGY

Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: a definitive study using only bone-erosive ACPA-negative rheumatoid arthritis

(2010) K. Ohmura et al.   RHEUMATOLOGY

Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease

(2010) Steve Eyre et al.   ARTHRITIS RESEARCH & THERAPY

Value of anti-modified citrullinated vimentin and third-generation anti-cyclic citrullinated peptide compared with second-generation anti-cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis and rheumatoid arthritis

(2009) Michael P. M. van der Linden et al.   ARTHRITIS AND RHEUMATISM

Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis

(2009) Diane van der Woude et al.   ARTHRITIS AND RHEUMATISM

Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: All alleles are important

(2009) Emeli Lundström et al.   ARTHRITIS AND RHEUMATISM

REL, encoding a member of the NF-κB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis

(2009) Peter K Gregersen et al.   NATURE GENETICS

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci

(2009) Annie McClure et al.   RHEUMATOLOGY

ThePTPN22620W allele confers susceptibility to systemic sclerosis: Findings of a large case–control study of European Caucasians and a meta‐analysis

(2008) P. Dieudé et al.   ARTHRITIS AND RHEUMATISM

Genome-wide association study of rheumatoid arthritis in the Spanish population:KLF12as a risk locus for rheumatoid arthritis susceptibility

(2008) Antonio Julià et al.   ARTHRITIS AND RHEUMATISM

Marked differences in fine specificity and isotype usage of the anti-citrullinated protein antibody in health and disease

(2008) Andreea Ioan-Facsinay et al.   ARTHRITIS AND RHEUMATISM

The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease

(2008) Matthew Roycroft et al.   CLINICAL ENDOCRINOLOGY

Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population

(2008) Akari Suzuki et al.   NATURE GENETICS

Advances in the genetics of rheumatoid arthritis point to subclassification into distinct disease subsets

(2008) Annette HM van der Helm-van Mil et al.   ARTHRITIS RESEARCH & THERAPY

Cytokines, autoantibodies and viral antibodies in premorbid and postdiagnostic sera from patients with rheumatoid arthritis: case-control study nested in a cohort of Norwegian blood donors

(2007) K T Jorgensen et al.   ANNALS OF THE RHEUMATIC DISEASES