TLR4 endogenous ligand MRP8/14 level in enthesitis-related arthritis and its association with disease activity and TLR4 expression

A subgroup of juvenile idiopathic arthritis patients who respond well to methotrexate are identified by the serum biomarker MRP8/14 protein

(2013) Halima Moncrieffe et al.   RHEUMATOLOGY

The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis

(2012) Dirk Holzinger et al.   ANNALS OF THE RHEUMATIC DISEASES

Membrane-Bound Toll-Like Receptors are Overexpressed in Peripheral Blood and Synovial Fluid Mononuclear Cells of Enthesitis-Related Arthritis Category of Juvenile Idiopathic Arthritis (JIA–ERA) Patients and Lead to Secretion of Inflammatory Mediators

(2012) Arpita Myles et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Soluble Receptor for Advanced Glycation Endproducts Is Decreased in Patients with Juvenile Idiopathic Arthritis (ERA Category) and Inversely Correlates with Disease Activity and S100A12 Levels

(2011) A. MYLES et al.   JOURNAL OF RHEUMATOLOGY

Profile of Indian Patients with Juvenile Onset Chronic Inflammatory Joint Disease Using the ILAR Classification Criteria for JIA: A Community-based Cohort Study

(2010) V. KUNJIR et al.   JOURNAL OF RHEUMATOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells

(2010) Karin Loser et al.   NATURE MEDICINE

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1β form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis

(2009) Michael Frosch et al.   ARTHRITIS AND RHEUMATISM

The role of Toll-like receptors in chronic inflammation

(2009) Stefan K. Drexler et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

TLRs and chronic inflammation

(2009) Caroline Ospelt et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Phagocyte-specific S100A8/A9 Protein Levels During Disease Exacerbations and Infections in Systemic Lupus Erythematosus

(2009) M. S. SOYFOO et al.   JOURNAL OF RHEUMATOLOGY

S100A12 is a novel molecular marker differentiating systemic-onset juvenile idiopathic arthritis from other causes of fever of unknown origin

(2008) Helmut Wittkowski et al.   ARTHRITIS AND RHEUMATISM

Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis

(2007) P L E M van Lent et al.   ANNALS OF THE RHEUMATIC DISEASES