Article
Immunology
Longxian Lv, Huiyong Jiang, Xiaoxiao Chen, Qiangqiang Wang, Kaicen Wang, Jianzhong Ye, Yating Li, Daiqiong Fang, Yingfeng Lu, Liya Yang, Silan Gu, Jianing Chen, Hongyan Diao, Ren Yan, Lanjuan Li
Summary: The study revealed significant alterations in the salivary microbiota of patients with primary biliary cholangitis (PBC), which may represent a contributing factor to oral inflammation and worsening liver function.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Medicine, General & Internal
Daniel Harding, Ming H. A. Chong, Nishant Lahoti, Carola M. Bigogno, Roshni Prema, Saidi A. Mohiddin, Federica Marelli-Berg
Summary: Dilated cardiomyopathy is a heart disease with unknown causes and limited treatment options. Immune dysfunction is believed to play a significant role in its development and progression. Current treatment focuses on symptom management and reducing the risk of sudden cardiac death.
JOURNAL OF INTERNAL MEDICINE
(2023)
Review
Medicine, Research & Experimental
Ashkan Rasouli-Saravani, Kasra Jahankhani, Shadi Moradi, Melika Gorgani, Zahra Shafaghat, Zahra Mirsanei, Amirreza Mehmandar, Rasoul Mirzaei
Summary: Emerging evidence suggests that microbiota and its metabolites, particularly gut microbiota, play a crucial role in immune responses and autoimmune diseases. Gut bacterial dysbiosis can lead to disease and altered microbiota metabolite synthesis, causing immunological and metabolic dysregulation. Among these metabolites, short-chain fatty acids (SCFAs) produced by gut microbiota have been linked to the pathophysiology of various autoimmune disorders. This review focuses on recent findings regarding the impact of microbiota SCFAs on autoimmune diseases.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Fisheries
Irene Salinas, Alvaro Fernandez-Montero, Yang Ding, J. Oriol Sunyer
Summary: Immunoglobulins play critical roles in the immune systems of jawed vertebrates, with IgT identified as playing a predominant role in fish mucosal immunity. Recent studies have highlighted the importance of secretory Igs in maintaining microbiota homeostasis and controlling pathogens at mucosal sites. This review aims to summarize the current status of fish Igs research since the discovery of IgT, while identifying future research directions.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Review
Nutrition & Dietetics
Shiqi Wang, Jialin Wu, Duo Ran, Guosen Ou, Yaokang Chen, Huachong Xu, Li Deng, Xiaoyin Chen
Summary: This study is the first bibliometric evaluation and systematic analysis of publications related to mucosal immunity and commensal microbiota in the past two decades. It summarizes the contributions of countries, institutions, and scholars in this field. The study found that the interaction between commensal microbiota and mucosal immunity plays a crucial role in regulating immune responses, maintaining communication between different microbiota and the host. Several hot topics in this field, such as the effects of metabolites on mucosal immunity, physiopathological phenomena of commensal microbiota, and the relationship between COVID-19 and mucosal immunity, have gained extensive attention in recent years.
Article
Fisheries
Syed Monzur Morshed, Tsung-Han Lee
Summary: The environment has a significant impact on fish as it affects the microbiome and mucosal immunity, which are crucial for their overall health. However, there is a lack of research on the interaction between the microbiome and mucosal immunity under different environmental conditions. This review summarizes the existing literature on the effects of environmental changes, such as temperature, salinity, dissolved oxygen, pH, and photoperiod, on the fish microbiome and mucosal immunity. Understanding the mucosal immunity-microbiome interaction can also enhance aquaculture practices during environmental stress.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Junhu Tai, Mun Soo Han, Jiwon Kwak, Tae Hoon Kim
Summary: The pathogenesis of nasal inflammatory diseases involves various factors such as anatomical structure, heredity, and environment, with nasal microbiota playing a key role in immune system functions and dysfunction impacting inflammation occurrence and development. Recent advancements in DNA sequencing, metabolomics, and proteomics combined with computational bioinformatics are aiding research in this area.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Immunology
Jingjie Wang, Jun Shen
Summary: The gut vascular barrier (GVB) is composed of gut vascular endothelial cells, enteric glial cells, and pericytes and plays a crucial role in nutrient absorption and preventing bacterial translocation. Dysfunction of the GVB has been correlated with various clinical pathologies, including Crohn's disease (CD). Extensive research has been carried out to understand the mechanisms of GVB dysfunction and its involvement in CD, but further analysis is needed to elucidate the specific roles of GVB in CD pathogenesis. Many studies have shown the effectiveness of different agents in protecting GVB integrity, offering potential treatment strategies for CD.
CLINICAL IMMUNOLOGY
(2023)
Review
Immunology
Dongjia Lin, Lisa Yang, Liling Wen, Huanzi Lu, Qianming Chen, Zhi Wang
Summary: Oral mucosal disease (OMD), also known as soft tissue oral disease, is a range of disorders affecting the mucosa and soft tissue in the oral cavity. The unclear etiology may involve dysbiosis of oral mucosa and saliva-resident microbiota, impacting immune response and epithelial barrier function, leading to OMD. Research suggests diverse oral microbial dysbiosis in different diseases, implying potential causal pathogens across various oral pathologies. This literature review explores how microbial dysbiosis interacts with mucosal adaptive immune cells and the epithelial barrier in OMD, focusing on representative OMDs including oral candidiasis, oral lichen planus, recurrent aphthous ulcer, oral leukoplakia, and oral squamous cell carcinoma.
MUCOSAL IMMUNOLOGY
(2021)
Review
Food Science & Technology
Weizhe Chen, Jie Wang, Liyu Du, Junjie Chen, Qikai Zheng, Pan Li, Bing Du, Xiang Fang, Zhenlin Liao
Summary: Kefir, a fermented food with probiotics, can regulate intestinal microbiota balance and enhance immune response to shape mucosal immunity. Its metabolites and microbial antigens can shape the mucosal immunity and regulate antibody levels to maintain intestinal homeostasis, affecting the occurrence of intestinal inflammation.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Immunology
Li-guo Ding, Guang-kun Han, Xin-you Wang, Ru-han Sun, Yong-yao Yu, Zhen Xu
Summary: This study investigated the composition of the teleost gallbladder microbiota and its potential role in mucosal immunity. The results showed that the gallbladder microbiome was similar to the gut microbiota. Infection induced inflammation and disrupted microbial homeostasis in the gallbladder. Beneficial bacteria from the Lactobacillales order increased in abundance in the bile microbial community, while the structure of the Mycoplasmatales order in the gut microbial community changed significantly.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Fisheries
Xi-Yue Ding, Cheng-Ye Wei, Zi-Yan Liu, Hong-Ling Yang, Fang Han, Yun-Zhang Sun
Summary: This study found that autochthonous Bacillus subtilis B0E9 and Enterococcus faecalis AT5 can improve liver health, serum and skin immunities, positively shape gut and skin mucosal microbiota, and enhance red-head disease resistance in yellow drum.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Microbiology
Olivia Briceno, Mauricio Gonzalez-Navarro, Nadia Montufar, Monserrat Chavez-Torres, Indira Abato, Ariana Espinosa-Sosa, Yuria Ablanedo-Terrazas, Yara Luna-Villalobos, Santiago Avila-Rios, Gustavo Reyes-Teran, Sandra Pinto-Cardoso
Summary: This study characterized immune cell populations and bacterial microbiota in adenoids, tonsils, and the oral cavity of PLWH and HIV-seronegative individuals. Differences in activated T cells, T helper cell populations, and discriminant genera were observed between PLWH and SN, while alpha diversity was comparable. HIV infection had a minor impact on bacterial community structure at each site.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Immunology
Yang Li, Fei Sun, Tian-Tian Yue, Fa-Xi Wang, Chun-Liang Yang, Jia-Hui Luo, Shan-Jie Rong, Fei Xiong, Shu Zhang, Cong-Yi Wang
Summary: In the context of Type 1 diabetes (T1D), beta cells actively participate in the initiation of autoimmune responses by producing modified neoantigens and interacting with immune cells, leading to the activation of autoreactive T cells. This antigen-presenting function of beta cells helps explain the tissue specificity of T1D and underscores the active roles of structural cells in immune-related disorders' pathogenesis.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Medicine, General & Internal
Qiaoyan Liu, Wei He, Ruqi Tang, Xiong Ma
Summary: Intestinal homeostasis relies on the interaction between the gut microbiota and the immune system. Evidence suggests that the gut microbiota plays a crucial role in autoimmune liver disease (AILD). Various mechanisms contribute to disruptions in intestinal homeostasis in AILD, including bacterial translocation and molecular mimicry. The gut and liver are exposed to microbial metabolic products, which can have different effects on liver immune pathologies. Abnormal microbiota-specific or associated immune responses are observed in AILD. Understanding the host-microbiota interactions is important for clinical practice in AILD, but challenges and controversies remain in this field.
CHINESE MEDICAL JOURNAL
(2022)
Article
Rheumatology
S. Louis Bridges, Steffen Gay
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
Joshua F. Baker, Daniel G. Baker
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
William Neal Roberts Jr, Edward R. Lew, Matthew H. Liang
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
Daniel A. Albert
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
Virginia D. Steen, Thomas A. Medsger
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
Patricia Woo, Ross E. Petty
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
H. James Williams, Grant W. Cannon, Daniel O. Clegg
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Biographical-Item
Rheumatology
Daniel J. Wallace
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
Ann K. Rosenthal, Mary E. Csuka, Paul Halverson
Summary: Dr. McCarty is a giant in the field of rheumatology. His clinical and scientific discoveries have had a major impact and benefited many patients. He has been an exceptional mentor and role model, influencing our clinical practice styles, the importance we place on clinical observation, and our approach to scientific questions.
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
Arthur Weinstein
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
Marc C. Hochberg
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
Richard M. Silver
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
Anthony M. Reginato, Michelle A. Petri, Jonathan Kay
Summary: Bauer and Ropes were influential figures in the field of rheumatology, making significant contributions through clinical observation and laboratory research. They were also exceptional mentors and leaders in the field.
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
Mary K. Crow, Josef S. Smolen
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)
Article
Rheumatology
James S. Louie
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2024)